Neuronal induction of the immunoproteasome in Huntington's disease M Díaz-Hernández, F Hernández, E Martín-Aparicio, P Gómez-Ramos, ... Journal of Neuroscience 23 (37), 11653-11661, 2003 | 325 | 2003 |
Extracellular tau is toxic to neuronal cells A Gómez-Ramos, M Díaz-Hernández, R Cuadros, F Hernández, J Avila FEBS letters 580 (20), 4842-4850, 2006 | 292 | 2006 |
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells A Gómez-Ramos, M Díaz-Hernández, A Rubio, MT Miras-Portugal, J Avila Molecular and Cellular Neuroscience 37 (4), 673-681, 2008 | 281 | 2008 |
Altered P2X7‐receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration M Díaz-Hernández, M Díez-Zaera, J Sánchez-Nogueiro, ... The FASEB Journal 23 (6), 1893-1906, 2009 | 274 | 2009 |
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease C Blazquez, A Chiarlone, O Sagredo, T Aguado, MR Pazos, E Resel, ... Brain 134 (1), 119-136, 2011 | 232 | 2011 |
Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice T Engel, R Gomez‐Villafuertes, K Tanaka, G Mesuret, A Sanz‐Rodriguez, ... The FASEB journal 26 (4), 1616-1628, 2012 | 223 | 2012 |
In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases JI Diaz-Hernandez, R Gomez-Villafuertes, M León-Otegui, ... Neurobiology of aging 33 (8), 1816-1828, 2012 | 219 | 2012 |
Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau M Díaz-Hernández, A Gómez-Ramos, A Rubio, R Gómez-Villafuertes, ... Journal of Biological Chemistry 285 (42), 32539-32548, 2010 | 175 | 2010 |
Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons M Díaz-Hernandez, A del Puerto, JI Díaz-Hernandez, M Diez-Zaera, ... Journal of cell science 121 (22), 3717-3728, 2008 | 173 | 2008 |
Increased neocortical expression of the P 2X7 receptor after status epilepticus and anticonvulsant effect of P 2X7 receptor antagonist A‐438079 A Jimenez‐Pacheco, G Mesuret, A Sanz‐Rodriguez, K Tanaka, ... Epilepsia 54 (9), 1551-1561, 2013 | 164 | 2013 |
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain S Ginés, M Bosch, S Marco, N Gavalda, M Díaz‐Hernández, JJ Lucas, ... European Journal of Neuroscience 23 (3), 649-658, 2006 | 162 | 2006 |
Transient P2X7 receptor antagonism produces lasting reductions in spontaneous seizures and gliosis in experimental temporal lobe epilepsy A Jimenez-Pacheco, M Diaz-Hernandez, M Arribas-Blázquez, ... Journal of Neuroscience 36 (22), 5920-5932, 2016 | 156 | 2016 |
Neuronal P2X7 receptor: involvement in neuronal physiology and pathology MT Miras-Portugal, Á Sebastián-Serrano, L de Diego García, ... Journal of Neuroscience 37 (30), 7063-7072, 2017 | 143 | 2017 |
Characteristics and consequences of muscarinic receptor activation by tau protein A Gómez-Ramos, M Díaz-Hernández, A Rubio, JI Díaz-Hernández, ... European Neuropsychopharmacology 19 (10), 708-717, 2009 | 126 | 2009 |
Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain M Díaz‐Hernández, AG Valera, MA Morán, P Gómez‐Ramos, ... Journal of neurochemistry 98 (5), 1585-1596, 2006 | 126 | 2006 |
P2X7 Receptors in Rat Brain: Presence in Synaptic Terminals and Granule Cells MT Miras-Portugal, M Díaz-Hernández, L Giráldez, C Hervás, ... Neurochemical research 28, 1597-1605, 2003 | 124 | 2003 |
Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons M Díez-Zaera, JI Díaz-Hernández, E Hernández-Álvarez, H Zimmermann, ... Molecular biology of the cell 22 (7), 1014-1024, 2011 | 122 | 2011 |
Diadenosine polyphosphate receptors: from rat and guinea-pig brain to human nervous system J Pintor, M Dı́az-Hernández, J Gualix, R Gómez-Villafuertes, F Hernando, ... Pharmacology & therapeutics 87 (2-3), 103-115, 2000 | 115 | 2000 |
Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation Z Ortega, M Díaz-Hernández, CJ Maynard, F Hernández, NP Dantuma, ... Journal of Neuroscience 30 (10), 3675-3688, 2010 | 112 | 2010 |
microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus EM Jimenez-Mateos, M Arribas-Blazquez, A Sanz-Rodriguez, ... Scientific reports 5 (1), 17486, 2015 | 108 | 2015 |