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Duuamene Nyimanu
Duuamene Nyimanu
Researcher, The University of Kansas Medical Center
在 cantab.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
7542019
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
4612021
International union of basic and clinical pharmacology. CVII. Structure and pharmacology of the apelin receptor with a recommendation that elabela/toddler is a second …
C Read, D Nyimanu, TL Williams, DJ Huggins, P Sulentic, RGC Macrae, ...
Pharmacological reviews 71 (4), 467-502, 2019
912019
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, AA Mathie, ...
British journal of pharmacology 180, S23-S144, 2023
702023
The therapeutic potential of apelin in kidney disease
FA Chapman, D Nyimanu, JJ Maguire, AP Davenport, DE Newby, ...
Nature Reviews Nephrology 17 (12), 840-853, 2021
582021
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension
P Yang, C Read, RE Kuc, D Nyimanu, TL Williams, A Crosby, ...
British journal of pharmacology 176 (9), 1206-1221, 2019
372019
Apelin peptides linked to anti‐serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo
C Read, P Yang, RE Kuc, D Nyimanu, TL Williams, RC Glen, LJ Holt, ...
Basic & Clinical Pharmacology & Toxicology 126, 96-103, 2020
222020
Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites
TL Williams, G Strachan, RGC Macrae, RE Kuc, D Nyimanu, AL Paterson, ...
Scientific Reports 11 (1), 24336, 2021
212021
Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans
D Nyimanu, RG Kay, P Sulentic, RE Kuc, P Ambery, L Jermutus, ...
Scientific Reports 9 (1), 19934, 2019
192019
Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer
VL Silva, A Kaassis, A Dehsorkhi, CR Koffi, M Severic, M Abdelhamid, ...
Biomaterials science 8 (9), 2420-2433, 2020
152020
Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection
TL Williams, MT Colzani, RGC Macrae, EL Robinson, S Bloor, ...
Communications Biology 4 (1), 926, 2021
132021
Apelin-36-[L28A] and Apelin-36-[L28C (30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor
D Nyimanu, RE Kuc, TL Williams, M Bednarek, P Ambery, L Jermutus, ...
Peptides 121, 170139, 2019
132019
The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation …
C Read, D Nyimanu, P Yang, RE Kuc, TL Williams, CM Fitzpatrick, ...
Frontiers in Pharmacology 11, 588669, 2021
122021
Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10
NE Owen, D Nyimanu, RE Kuc, PD Upton, NW Morrell, GJ Alexander, ...
Peptides 136, 170440, 2021
92021
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function
D Nyimanu, FA Chapman, PJ Gallacher, RE Kuc, TL Williams, DE Newby, ...
British journal of clinical pharmacology 88 (12), 5295-5306, 2022
62022
In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide …
D Nyimanu, RG Kay, RE Kuc, AJH Brown, FM Gribble, JJ Maguire, ...
Peptides 145, 170642, 2021
52021
The role of claudin-2 in kidney function and dysfunction
D Nyimanu, C Behm, S Choudhury, ASL Yu
Biochemical Society Transactions 51 (4), 1437-1445, 2023
32023
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors
HA Stephen P, A Christopoulos, PD Anthony, E Kelly, A Mathie, AP John, ...
BRITISH JOURNAL OF PHARMACOLOGY 178, 2021
22021
BS16 A novel fluorescent apelin ligand tracks apelin receptor internalisation
E O’Flaherty, T Williams, D Nyimanu, R Macrae, H Currinn, J Brown, ...
Heart 105 (Suppl 6), A151-A151, 2019
12019
International Union of Basic and Clinical Pharmacology XXX. Structure and pharmacology of the apelin receptor with a recommendation that Elabela/Toddler is a second endogenous …
A Davenport, C Read, D Nyimanu, T Williams, D Huggins, P Sulentic, ...
American Society for Pharmacology and Experimental Therapeutics, 2019
12019
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