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Yan Helen Hu
Yan Helen Hu
Eisai, Inc.
在 eisai.com 的电子邮件经过验证
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引用次数
引用次数
年份
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
Y Zheng, PA Valdez, DM Danilenko, Y Hu, SM Sa, Q Gong, AR Abbas, ...
Nature medicine 14 (3), 282-289, 2008
22212008
The IL‐17 pathway as a major therapeutic target in autoimmune diseases
Y Hu, F Shen, NK Crellin, W Ouyang
Annals of the New York Academy of Sciences 1217 (1), 60-76, 2011
1842011
IL-17RC is required for IL-17A–and IL-17F–dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis
Y Hu, N Ota, I Peng, CJ Refino, DM Danilenko, P Caplazi, W Ouyang
The Journal of Immunology 184 (8), 4307-4316, 2010
1722010
The IL-17 family cytokines in immunity and disease
R Pappu, V Ramirez-Carrozzi, N Ota, W Ouyang, Y Hu
Journal of clinical immunology 30, 185-195, 2010
1682010
A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity …
T West, KM Kirmess, MR Meyer, MS Holubasch, SS Knapik, Y Hu, ...
Molecular neurodegeneration 16 (1), 30, 2021
1522021
Preclinical and clinical development of ABBV-8E12, a humanized anti-tau antibody, for treatment of Alzheimer’s disease and other tauopathies
T West, Y Hu, PB Verghese, RJ Bateman, JB Braunstein, I Fogelman, ...
J Prev Alzheimers Dis 4 (4), 236-241, 2017
1512017
Comparative proteomic analysis of intra-and interindividual variation in human cerebrospinal fluid
Y Hu, JP Malone, AM Fagan, RR Townsend, DM Holtzman
Molecular & Cellular Proteomics 4 (12), 2000-2009, 2005
1492005
Molecular Characterization of a Metastatic Neuroendocrine Cell Cancer Arising in the Prostates of Transgenic Mice* 210
Y Hu, JE Ippolito, EM Garabedian, PA Humphrey, JI Gordon
Journal of Biological Chemistry 277 (46), 44462-44474, 2002
1232002
Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy
K Yanamandra, TK Patel, H Jiang, S Schindler, JD Ulrich, AL Boxer, ...
Science translational medicine 9 (386), 2017
922017
Helicobacter pylori attaches to NeuAcα2, 3Galβ1, 4 glycoconjugates produced in the stomach of transgenic mice lacking parietal cells
AJ Syder, JL Guruge, Q Li, Y Hu, CM Oleksiewicz, RG Lorenz, SM Karam, ...
Molecular cell 3 (3), 263-274, 1999
921999
The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis
KM Kirmess, MR Meyer, MS Holubasch, SS Knapik, Y Hu, EN Jackson, ...
Clinica Chimica Acta 519, 267-275, 2021
822021
Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease
Y Hu, A Hosseini, JSK Kauwe, J Gross, NJ Cairns, AM Goate, AM Fagan, ...
PROTEOMICS–Clinical Applications 1 (11), 1373-1384, 2007
742007
Assessment of a plasma amyloid probability score to estimate amyloid positron emission tomography findings among adults with cognitive impairment
Y Hu, KM Kirmess, MR Meyer, GD Rabinovici, C Gatsonis, BA Siegel, ...
JAMA network open 5 (4), e228392-e228392, 2022
582022
RNA interference of achaete–scute homolog 1 in mouse prostate neuroendocrine cells reveals its gene targets and DNA binding sites
Y Hu, T Wang, GD Stormo, JI Gordon
Proceedings of the National Academy of Sciences 101 (15), 5559-5564, 2004
572004
Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape
H Hampel, Y Hu, J Cummings, S Mattke, T Iwatsubo, A Nakamura, ...
Neuron 111 (18), 2781-2799, 2023
552023
The foundation and architecture of precision medicine in neurology and psychiatry
H Hampel, P Gao, J Cummings, N Toschi, PM Thompson, Y Hu, M Cho, ...
Trends in Neurosciences 46 (3), 176-198, 2023
502023
Novel therapeutic targets along the Th17 pathway
W Ouyang, E Filvaroff, Y Hu, J Grogan
European journal of immunology 39 (3), 670-675, 2009
412009
Cross-reactive and bispecific anti-IL-17A/F antibodies
Y Chen, YH Hu, W Ouyang, S Stawicki, Y Wu
US Patent 8,790,642, 2014
212014
[O2–17–01]: RESULTS OF A PHASE 1, SINGLE ASCENDING DOSE, PLACEBO‐CONTROLLED STUDY OF ABBV‐8E12 IN PATIENTS WITH PROGRESSIVE SUPRANUCLEAR PALSY AND PHASE 2 STUDY DESIGN IN EARLY …
K Budur, T West, JB Braunstein, I Fogelman, YM Bordelon, I Litvan, ...
Alzheimer's & Dementia 13 (7S_Part_12), P599-P600, 2017
102017
Can we use blood biomarkers as entry criteria and for monitoring drug treatment effects in clinical trials? A report from the EU/US CTAD task force
D Angioni, O Hansson, RJ Bateman, C Rabe, M Toloue, JB Braunstein, ...
The Journal of Prevention of Alzheimer's Disease 10 (3), 418-425, 2023
92023
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