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John Dudley Isaacs
John Dudley Isaacs
Professor of Clinical Rheumatology, Newcastle University
在 ncl.ac.uk 的电子邮件经过验证
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引用次数
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The value of sonography in the detection of bone erosions in patients with rheumatoid arthritis: a comparison with conventional radiography
RJ Wakefield, WW Gibbon, PG Conaghan, P O'Connor, D McGonagle, ...
Arthritis & Rheumatism 43 (12), 2762-2770, 2000
10672000
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
Nature 464 (7289), 713-720, 2010
9352010
Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells
WF Ng, PJ Duggan, F Ponchel, G Matarese, G Lombardi, AD Edwards, ...
Blood, The Journal of the American Society of Hematology 98 (9), 2736-2744, 2001
8002001
Real-time PCR based on SYBR-Green I fluorescence: an alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene …
F Ponchel, C Toomes, K Bransfield, FT Leong, SH Douglas, SL Field, ...
BMC biotechnology 3, 1-13, 2003
6002003
Cytokines in rheumatoid arthritis—shaping the immunological landscape
IB McInnes, CD Buckley, JD Isaacs
Nature Reviews Rheumatology 12 (1), 63-68, 2016
5582016
Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis
MH Buch, JS Smolen, N Betteridge, FC Breedveld, G Burmester, T Dörner, ...
Annals of the rheumatic diseases 70 (6), 909-920, 2011
5212011
Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial
J Kremer, ZG Li, S Hall, R Fleischmann, M Genovese, E Martin-Mola, ...
Annals of internal medicine 159 (4), 253-261, 2013
5072013
Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised …
IB McInnes, J Sieper, J Braun, P Emery, D van der Heijde, JD Isaacs, ...
Annals of the rheumatic diseases 73 (2), 349-356, 2014
4652014
Elucidation of the relationship between synovitis and bone damage: a randomized magnetic resonance imaging study of individual joints in patients with early rheumatoid arthritis
PG Conaghan, P O'Connor, D McGonagle, P Astin, RJ Wakefield, ...
Arthritis & Rheumatism 48 (1), 64-71, 2003
4632003
Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells
MA Haniffa, XN Wang, U Holtick, M Rae, JD Isaacs, AM Dickinson, ...
The Journal of Immunology 179 (3), 1595-1604, 2007
4592007
Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study
J Collerton, C Martin-Ruiz, K Davies, CM Hilkens, J Isaacs, C Kolenda, ...
Mechanisms of ageing and development 133 (6), 456-466, 2012
4492012
Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid …
P Emery, A Deodhar, WF Rigby, JD Isaacs, B Combe, AJ Racewicz, ...
Annals of the rheumatic diseases 69 (9), 1629-1635, 2010
4392010
Integrated safety in tocilizumab clinical trials
MH Schiff, JM Kremer, A Jahreis, E Vernon, JD Isaacs, ...
Arthritis research & therapy 13, 1-13, 2011
4172011
Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers
PM Brown, AG Pratt, JD Isaacs
Nature Reviews Rheumatology 12 (12), 731-742, 2016
4082016
Novel therapies for immune-mediated inflammatory diseases: what can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis …
KF Baker, JD Isaacs
Annals of the rheumatic diseases 77 (2), 175-187, 2018
3932018
Humanised monoclonal antibody therapy for rheumatoid arthritis
JD Isaacs, G Hale, SP Cobbold, H Waldmann, RA Watts, BL Hazleman, ...
The Lancet 340 (8822), 748-752, 1992
3841992
Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells.
MG Wing, T Moreau, J Greenwood, RM Smith, G Hale, J Isaacs, ...
The Journal of clinical investigation 98 (12), 2819-2826, 1996
3601996
Early rheumatoid arthritis is associated with a deficit in the CD4 + CD25 high regulatory T cell population in peripheral blood
CA Lawson, AK Brown, V Bejarano, SH Douglas, CH Burgoyne, ...
Rheumatology 45 (10), 1210-1217, 2006
3432006
Biologic therapies in rheumatology: lessons learned, future directions
V Strand, R Kimberly, JD Isaacs
Nature Reviews Drug Discovery 6 (1), 75-92, 2007
3412007
Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
GM Bell, AE Anderson, J Diboll, R Reece, O Eltherington, RA Harry, ...
Annals of the rheumatic diseases 76 (1), 227-234, 2017
3222017
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