Chemokine-directed tumor microenvironment modulation in cancer immunotherapy P Bule, SI Aguiar, F Aires-Da-Silva, JNR Dias International journal of molecular sciences 22 (18), 9804, 2021 | 119 | 2021 |
Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition I Venditto, AS Luis, M Rydahl, J Schückel, VO Fernandes, ... Proceedings of the National Academy of Sciences 113 (26), 7136-7141, 2016 | 74 | 2016 |
Complexity of the Ruminococcus flavefaciens FD-1 cellulosome reflects an expansion of family-related protein-protein interactions V Israeli-Ruimy, P Bule, S Jindou, B Dassa, S Moraïs, I Borovok, Y Barak, ... Scientific Reports 7 (1), 42355, 2017 | 47 | 2017 |
Low doses of exogenous xylanase improve the nutritive value of triticale-based diets for broilers AR Mendes, T Ribeiro, BA Correia, P Bule, B Macas, L Falcao, JPB Freire, ... Journal of Applied Poultry Research 22 (1), 92-99, 2013 | 45 | 2013 |
From cancer therapy to winemaking: The molecular structure and applications of β-glucans and β-1, 3-glucanases C Caseiro, JNR Dias, CMG de Andrade Fontes, P Bule International Journal of Molecular Sciences 23 (6), 3156, 2022 | 43 | 2022 |
Cellulosome assembly: paradigms are meant to be broken! P Bule, VMR Pires, CMGA Fontes, VD Alves Current opinion in structural biology 49, 154-161, 2018 | 34 | 2018 |
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo C de Boer, Z Armstrong, VAJ Lit, U Barash, G Ruijgrok, I Boyango, ... Proceedings of the National Academy of Sciences 119 (31), e2203167119, 2022 | 31 | 2022 |
Stability and ligand promiscuity of type A carbohydrate-binding modules are illustrated by the structure of Spirochaeta thermophila StCBM64C VMR Pires, PMM Pereira, JLA Brás, M Correia, V Cardoso, P Bule, ... Journal of Biological Chemistry 292 (12), 4847-4860, 2017 | 29 | 2017 |
Diverse specificity of cellulosome attachment to the bacterial cell surface JLA Brás, BA Pinheiro, K Cameron, F Cuskin, A Viegas, S Najmudin, ... Scientific reports 6 (1), 38292, 2016 | 28 | 2016 |
Cell-surface attachment of bacterial multienzyme complexes involves highly dynamic protein-protein anchors K Cameron, S Najmudin, VD Alves, EA Bayer, SP Smith, P Bule, H Waller, ... Journal of Biological Chemistry 290 (21), 13578-13590, 2015 | 27 | 2015 |
Recalcitrant cell wall of Ulva lactuca seaweed is degraded by a single ulvan lyase from family 25 of polysaccharide lyases MM Costa, LB Pio, P Bule, VA Cardoso, M Duarte, CM Alfaia, DF Coelho, ... Animal Nutrition 9, 184-192, 2022 | 24 | 2022 |
Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes P Bule, VD Alves, V Israeli-Ruimy, AL Carvalho, LMA Ferreira, SP Smith, ... Scientific reports 7 (1), 759, 2017 | 24 | 2017 |
Single binding mode integration of hemicellulose-degrading enzymes via adaptor scaffoldins in Ruminococcus flavefaciens cellulosome P Bule, VD Alves, A Leitão, LMA Ferreira, EA Bayer, SP Smith, HJ Gilbert, ... Journal of Biological Chemistry 291 (52), 26658-26669, 2016 | 22 | 2016 |
An individual alginate lyase is effective in the disruption of Laminaria digitata recalcitrant cell wall M Costa, L Pio, P Bule, V Cardoso, CM Alfaia, D Coelho, J Brás, ... Scientific Reports 11 (1), 9706, 2021 | 21 | 2021 |
Cellulosomes: highly efficient cellulolytic complexes VD Alves, CMGA Fontes, P Bule Macromolecular protein complexes III: structure and function, 323-354, 2021 | 21 | 2021 |
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action P Bule, L Chuzel, E Blagova, L Wu, MA Gray, B Henrissat, E Rapp, ... Nature Communications 10 (1), 4816, 2019 | 19 | 2019 |
Structure–function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes P Bule, K Cameron, JAM Prates, LMA Ferreira, SP Smith, HJ Gilbert, ... Journal of Biological Chemistry 293 (11), 4201-4212, 2018 | 18 | 2018 |
Combined crystal structure of a type I cohesin: Mutation and affinity binding studies reveal structural determinants of cohesin-dockerin specificities K Cameron, JY Weinstein, O Zhivin, P Bule, SJ Fleishman, VD Alves, ... Journal of Biological Chemistry 290 (26), 16215-16225, 2015 | 17 | 2015 |
A dual cohesin–dockerin complex binding mode in Bacteroides cellulosolvens contributes to the size and complexity of its cellulosome M Duarte, A Viegas, VD Alves, JAM Prates, LMA Ferreira, S Najmudin, ... Journal of Biological Chemistry 296, 2021 | 16 | 2021 |
Molecular determinants of substrate specificity revealed by the structure of Clostridium thermocellum arabinofuranosidase 43A from glycosyl hydrolase family 43 subfamily 16 A Goyal, S Ahmed, K Sharma, V Gupta, P Bule, VD Alves, CMGA Fontes, ... Acta Crystallographica Section D: Structural Biology 72 (12), 1281-1289, 2016 | 15 | 2016 |