Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse SR Hingorani, EF Petricoin, A Maitra, V Rajapakse, C King, MA Jacobetz, ... Cancer cell 4 (6), 437-450, 2003 | 2799 | 2003 |
The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors HC Crawford, BM Fingleton, LA Rudolph-Owen, KJH Goss, B Rubinfeld, ... Oncogene 18 (18), 2883-2891, 1999 | 936 | 1999 |
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1 V Noë, B Fingleton, K Jacobs, HC Crawford, S Vermeulen, W Steelant, ... Journal of cell science 114 (1), 111-118, 2001 | 926 | 2001 |
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell–and patient-derived tumor organoids L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ... Nature medicine 21 (11), 1364-1371, 2015 | 731 | 2015 |
Inhibition of RhoA by p120 catenin PZ Anastasiadis, SY Moon, MA Thoreson, DJ Mariner, HC Crawford, ... Nature cell biology 2 (9), 637-644, 2000 | 612 | 2000 |
EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 540 | 2012 |
Matrix metalloproteinase-7–dependent release of tumor necrosis factor-α in a model of herniated disc resorption H Haro, HC Crawford, B Fingleton, K Shinomiya, DM Spengler, ... The Journal of clinical investigation 105 (2), 143-150, 2000 | 499 | 2000 |
Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin) R Agnihotri, HC Crawford, H Haro, LM Matrisian, MC Havrda, L Liaw Journal of Biological Chemistry 276 (30), 28261-28267, 2001 | 498 | 2001 |
The p120 ctn -binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG … JM Daniel, CM Spring, HC Crawford, AB Reynolds, A Baig Nucleic acids research 30 (13), 2911-2919, 2002 | 354 | 2002 |
NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer IIC Chio, SM Jafarnejad, M Ponz-Sarvise, Y Park, K Rivera, W Palm, ... Cell 166 (4), 963-976, 2016 | 352 | 2016 |
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ... Cell metabolism 29 (6), 1390-1399. e6, 2019 | 340 | 2019 |
Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals CT Rubin, E Capilla, YK Luu, B Busa, H Crawford, DJ Nolan, V Mittal, ... Proceedings of the National Academy of Sciences 104 (45), 17879-17884, 2007 | 331 | 2007 |
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs GY Liou, H Döppler, B Necela, M Krishna, HC Crawford, M Raimondo, ... Journal of Cell Biology 202 (3), 563-577, 2013 | 299 | 2013 |
Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer JL Saloman, KM Albers, D Li, DJ Hartman, HC Crawford, EA Muha, ... Proceedings of the National Academy of Sciences 113 (11), 3078-3083, 2016 | 296 | 2016 |
Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer Y Song, MK Washington, HC Crawford Cancer research 70 (5), 2115-2125, 2010 | 282 | 2010 |
Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas HC Crawford, CR Scoggins, MK Washington, LM Matrisian, SD Leach The Journal of clinical investigation 109 (11), 1437-1444, 2002 | 281 | 2002 |
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ... Cancer discovery 10 (3), 422-439, 2020 | 280 | 2020 |
Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression. HC Crawford, LM Matrisian Invasion & metastasis 14 (1-6), 234-245, 1994 | 277 | 1994 |
Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells HC Crawford, LM Matrisian Enzyme and Protein 49 (1-3), 20-37, 1996 | 268 | 1996 |
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells CS Guy, KM Vignali, J Temirov, ML Bettini, AE Overacre, M Smeltzer, ... Nature immunology 14 (3), 262-270, 2013 | 263 | 2013 |