The Cryptococcus neoformans capsule: a sword and a shield TR O'Meara, JA Alspaugh Clinical microbiology reviews 25 (3), 387-408, 2012 | 328 | 2012 |
Global analysis of fungal morphology exposes mechanisms of host cell escape TR O’Meara, AO Veri, T Ketela, B Jiang, T Roemer, LE Cowen Nature communications 6 (1), 1-10, 2015 | 202 | 2015 |
Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule TR O'Meara, D Norton, MS Price, C Hay, MF Clements, CB Nichols, ... PLoS pathogens 6 (2), e1000776, 2010 | 202 | 2010 |
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 C Mirabelli, JW Wotring, CJ Zhang, SM McCarty, R Fursmidt, CD Pretto, ... Proceedings of the National Academy of Sciences 118 (36), 2021 | 162 | 2021 |
Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli LH Okagaki, Y Wang, ER Ballou, TR O'Meara, YS Bahn, JA Alspaugh, ... Eukaryotic cell 10 (10), 1306-1316, 2011 | 120 | 2011 |
Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses TR O'Meara, SM Holmer, K Selvig, F Dietrich, JA Alspaugh MBio 4 (1), 10.1128/mbio. 00522-12, 2013 | 112 | 2013 |
Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host TR O'Meara, C Hay, MS Price, S Giles, JA Alspaugh Eukaryotic cell 9 (8), 1193-1202, 2010 | 96 | 2010 |
The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host TR O'Meara, W Xu, KM Selvig, MJ O'Meara, AP Mitchell, JA Alspaugh Molecular and Cellular Biology 34 (4), 673-684, 2014 | 90 | 2014 |
Adaptive immunity induces mutualism between commensal eukaryotes KS Ost, TR O’Meara, WZ Stephens, T Chiaro, H Zhou, J Penman, R Bell, ... Nature 596 (7870), 114-118, 2021 | 82 | 2021 |
The Hsp90 chaperone network modulates Candida virulence traits TR O’Meara, N Robbins, LE Cowen Trends in microbiology 25 (10), 809-819, 2017 | 75 | 2017 |
The Cryptococcus neoformans Alkaline Response Pathway: Identification of a Novel Rim Pathway Activator KS Ost, TR O’Meara, N Huda, SK Esher, JA Alspaugh Plos genetics 11 (4), e1005159, 2015 | 74 | 2015 |
Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies EJ Polvi, X Li, TR O’Meara, MD Leach, LE Cowen Cellular and Molecular Life Sciences 72, 2261-2287, 2015 | 72 | 2015 |
Fitness trade-offs associated with the evolution of resistance to antifungal drug combinations JA Hill, TR O’Meara, LE Cowen Cell Reports 10 (5), 809-819, 2015 | 69 | 2015 |
H sp90‐dependent regulatory circuitry controlling temperature‐dependent fungal development and virulence TR O'Meara, LE Cowen Cellular microbiology 16 (4), 473-481, 2014 | 56 | 2014 |
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ... MBio 9 (4), 10.1128/mbio. 01581-18, 2018 | 55 | 2018 |
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space AO Veri, Z Miao, RS Shapiro, F Tebbji, TR O’Meara, SH Kim, J Colazo, ... PLoS genetics 14 (3), e1007270, 2018 | 44 | 2018 |
Mapping the Hsp90 genetic network reveals ergosterol biosynthesis and phosphatidylinositol-4-kinase signaling as core circuitry governing cellular stress TR O’Meara, AO Veri, EJ Polvi, X Li, SF Valaei, S Diezmann, LE Cowen PLoS genetics 12 (6), e1006142, 2016 | 44 | 2016 |
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase J MacAlpine, M Daniel-Ivad, Z Liu, J Yano, NM Revie, RT Todd, ... Nature communications 12 (1), 6151, 2021 | 43 | 2021 |
Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31 X Li, N Robbins, TR O'Meara, LE Cowen Molecular microbiology 103 (4), 635-656, 2017 | 40 | 2017 |
Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes ME Maxson, X Naj, TR O'Meara, JD Plumb, LE Cowen, S Grinstein Elife 7, e34798, 2018 | 37 | 2018 |