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Nicole Krentz
Nicole Krentz
Assistant Professor, Faculty of Pharmaceutical Sciences, University of British Columbia
在 ubc.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics
NAJ Krentz, AL Gloyn
Nature Reviews Endocrinology 16 (4), 202-212, 2020
1182020
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
OP Dwivedi, M Lehtovirta, B Hastoy, V Chandra, NAJ Krentz, S Kleiner, ...
Nature genetics 51 (11), 1596-1606, 2019
1172019
Single-cell transcriptome profiling of mouse and hESC-derived pancreatic progenitors
NAJ Krentz, MYY Lee, EE Xu, SLJ Sproul, A Maslova, S Sasaki, FC Lynn
Stem cell reports 11 (6), 1551-1564, 2018
1112018
Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors
NAJ Krentz, D van Hoof, Z Li, A Watanabe, M Tang, C Nian, MS German, ...
Developmental cell 41 (2), 129-142. e6, 2017
932017
TALEN/CRISPR-Mediated eGFP Knock-In Add-On at the OCT4 Locus Does Not Impact Differentiation of Human Embryonic Stem Cells towards Endoderm
NAJ Krentz, C Nian, FC Lynn
PloS one 9 (12), e114275, 2014
432014
Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells
PV Sabatini, NAJ Krentz, B Zarrouki, CY Westwell-Roper, C Nian, RA Uy, ...
Diabetes 62 (8), 2808-2820, 2013
402013
SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models
EE Xu, NAJ Krentz, S Tan, SZ Chow, M Tang, C Nian, FC Lynn
Diabetologia 58, 1013-1023, 2015
362015
Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering
NAJ Krentz, LD Shea, MO Huising, JAM Shaw
The Lancet Diabetes & Endocrinology 9 (10), 708-724, 2021
262021
TrxG complex catalytic and non-catalytic activity play distinct roles in pancreas progenitor specification and differentiation
SA Campbell, CL McDonald, NAJ Krentz, FC Lynn, BG Hoffman
Cell reports 28 (7), 1830-1844. e6, 2019
132019
77-Ins2 Gene Bursting Activity Defines a Mature β-Cell State
H Modi, J Chu, S Skovsø, C Ellis, NAJ Krentz, Y Zhao, HH Cen, ...
Canadian Journal of Diabetes 44 (7), S31, 2020
102020
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
KK Mattis, NAJ Krentz, C Metzendorf, F Abaitua, AF Spigelman, H Sun, ...
Diabetologia 66 (4), 674-694, 2023
82023
A regulatory network controls nephrocan expression and midgut patterning
J Hou, W Wei, RS Saund, P Xiang, TJ Cunningham, Y Yi, O Alder, ...
Development 141 (19), 3772-3781, 2014
82014
Dynamic Ins2 Gene Activity Defines β-Cell Maturity States
CMJ Chu, H Modi, C Ellis, NAJ Krentz, S Skovsø, YB Zhao, H Cen, ...
Diabetes 71 (12), 2612-2631, 2022
72022
PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development
HH Lau, NAJ Krentz, F Abaitua, M Perez-Alcantara, JW Chan, J Ajeian, ...
Nature Communications 14 (1), 6119, 2023
42023
Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding
TA Alghamdi, NAJ Krentz, N Smith, AF Spigelman, V Rajesh, A Jha, ...
Molecular Metabolism 66, 101621, 2022
32022
Improvements in stem cell to beta-cell differentiation for the treatment of diabetes
NAJ Krentz
Journal of Immunology and Regenerative Medicine 12, 100043, 2021
32021
Dynamic Ins2 gene activity defines β cell maturity states
H Modi, CM Jamie Chu, S Skovsø, C Ellis, NAJ Krentz, YB Zhao, H Cen, ...
bioRxiv, 702589, 2019
22019
Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model.
M Jaffredo, NAJ Krentz, B Champon, CE Duff, S Nawaz, N Beer, ...
Diabetes, db230776, 2024
12024
PAX4 loss of function alters human endocrine cell development and influences diabetes risk
HH Lau, NAJ Krentz, F Abaitua, M Perez-Alcantara, JW Chan, J Ajeian, ...
bioRxiv, 2022.05. 15.491987, 2022
12022
Imaging Ins2 gene activity and single-cell RNA sequencing reveal heterogeneous beta cell states
H Modi, H Cen, S Skovso, X Hu, N Krentz, D Dionne, S Xuan, M Huising, ...
DIABETOLOGIA 61, S17-S17, 2018
12018
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