Pseudotime ordering of single human β-cells reveals states of insulin production and unfolded protein response Y Xin, G Dominguez Gutierrez, H Okamoto, J Kim, AH Lee, C Adler, M Ni, ... Diabetes 67 (9), 1783-1794, 2018 | 185 | 2018 |
An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick … AB Munkacsi, FW Chen, MA Brinkman, K Higaki, GD Gutiérrez, ... Journal of Biological Chemistry 286 (27), 23842-23851, 2011 | 125 | 2011 |
Pancreatic β cell identity requires continual repression of non–β cell programs GD Gutiérrez, AS Bender, V Cirulli, TL Mastracci, SM Kelly, A Tsirigos, ... The Journal of clinical investigation 127 (1), 244-259, 2017 | 123 | 2017 |
Heterogeneity of the pancreatic beta cell GD Gutierrez, J Gromada, L Sussel Frontiers in genetics 8, 22, 2017 | 110 | 2017 |
LIM domain–binding 1 maintains the terminally differentiated state of pancreatic β cells BN Ediger, HW Lim, C Juliana, DN Groff, LQT Williams, G Dominguez, ... The Journal of clinical investigation 127 (1), 215-229, 2017 | 69 | 2017 |
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity S Kleiner, D Gomez, B Megra, E Na, R Bhavsar, K Cavino, Y Xin, J Rojas, ... Proceedings of the National Academy of Sciences 115 (32), E7642-E7649, 2018 | 62 | 2018 |
Genetic evidence that Nkx2. 2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development AJ Churchill, GD Gutierrez, RA Singer, DS Lorberbaum, KA Fischer, ... Elife 6, e20010, 2017 | 50 | 2017 |
Heterogeneity of human pancreatic β-cells G Dominguez-Gutierrez, Y Xin, J Gromada Molecular Metabolism 27, S7-S14, 2019 | 48 | 2019 |
Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition J Kim, G Dominguez Gutierrez, Y Xin, K Cavino, B Sung, B Sipos, ... Endocrinology 160 (5), 979-988, 2019 | 28 | 2019 |
Gene Signature of the Human Pancreatic ε Cell G Dominguez Gutierrez, J Kim, AH Lee, J Tong, JJ Niu, SM Gray, Y Wei, ... Endocrinology 159 (12), 4023-4032, 2018 | 26 | 2018 |
Gene Signature of Proliferating Human Pancreatic α Cells G Dominguez Gutierrez, Y Xin, H Okamoto, J Kim, AH Lee, M Ni, C Adler, ... Endocrinology 159 (9), 3177-3186, 2018 | 14 | 2018 |
Gene signature of proliferating human pancreatic a cells GD Gutierrez, Y Xin, H Okamoto, J Kim, AH Lee, M Ni, C Adler, ... Endocrinology 159, 3177-3186, 2018 | 10 | 2018 |
Interruption of the intratumor CD8+ T cell: Treg crosstalk improves the efficacy of PD-1 immunotherapy SN Geels, A Moshensky, RS Sousa, C Murat, MA Bustos, BL Walker, ... Cancer Cell 42 (6), 1051-1066. e7, 2024 | 1 | 2024 |
Interruption of the Intratumor CD8: Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy SN Geels, A Moshensky, RS Sousa, BL Walker, R Singh, G Gutierrez, ... bioRxiv, 2023.05. 15.540889, 2023 | | 2023 |
Compositions and Methods for Treatment of Disorders Associated with Repetitive DNA GA Dokshin, M Heidenreich, N Abdul-Manan, L Gan, J Liu, R Guoxiang, ... US Patent App. 17/681,138, 2022 | | 2022 |
Compositions and Methods for Treatment of Duchenne Muscular Dystrophy J Gromada, T Fulga, A McVie-Wylie, GD Gutierrez, Y Xin, F Bolukbasi, ... US Patent App. 17/469,665, 2022 | | 2022 |