β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes AE Butler, J Janson, S Bonner-Weir, R Ritzel, RA Rizza, PC Butler Diabetes 52 (1), 102-110, 2003 | 5548 | 2003 |
Disruption of IRS-2 causes type 2 diabetes in mice DJ Withers, JS Gutierrez, H Towery, DJ Burks, JM Ren, S Previs, Y Zhang, ... Nature 391 (6670), 900-904, 1998 | 2163 | 1998 |
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. G Xu, DA Stoffers, JF Habener, S Bonner-Weir Diabetes 48 (12), 2270-2276, 1999 | 1640 | 1999 |
Translational control is required for the unfolded protein response and in vivo glucose homeostasis D Scheuner, B Song, E McEwen, C Liu, R Laybutt, P Gillespie, ... Molecular cell 7 (6), 1165-1176, 2001 | 1632 | 2001 |
In vitro cultivation of human islets from expanded ductal tissue S Bonner-Weir, M Taneja, GC Weir, K Tatarkiewicz, KH Song, A Sharma, ... Proceedings of the National Academy of Sciences 97 (14), 7999-8004, 2000 | 1546 | 2000 |
Five stages of evolving beta-cell dysfunction during progression to diabetes GC Weir, S Bonner-Weir Diabetes 53 (suppl_3), S16-S21, 2004 | 1500 | 2004 |
p16INK4a induces an age-dependent decline in islet regenerative potential J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ... Nature 443 (7110), 453-457, 2006 | 1111 | 2006 |
A second pathway for regeneration of adult exocrine and endocrine pancreas: a possible recapitulation of embryonic development S Bonner-Weir, LA Baxter, GT Schuppin, FE Smith Diabetes 42 (12), 1715-1720, 1993 | 891 | 1993 |
Dynamics of β-cell mass in the growing rat pancreas: estimation with a simple mathematical model DT Finegood, L Scaglia, S Bonner-Weir Diabetes 44 (3), 249-256, 1995 | 849 | 1995 |
Selective β-cell loss and α-cell expansion in patients with type 2 diabetes mellitus in Korea KH Yoon, SH Ko, JH Cho, JM Lee, YB Ahn, KH Song, SJ Yoo, MI Kang, ... The Journal of Clinical Endocrinology & Metabolism 88 (5), 2300-2308, 2003 | 844 | 2003 |
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. DA Stoffers, TJ Kieffer, MA Hussain, DJ Drucker, S Bonner-Weir, ... Diabetes 49 (5), 741-748, 2000 | 810 | 2000 |
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. A Pick, J Clark, C Kubstrup, M Levisetti, W Pugh, S Bonner-Weir, ... Diabetes 47 (3), 358-364, 1998 | 793 | 1998 |
Chronic hyperglycemia triggers loss of pancreatic β cell differentiation in an animal model of diabetes JC Jonas, A Sharma, W Hasenkamp, H Ilkova, G Patane, R Laybutt, ... Journal of Biological Chemistry 274 (20), 14112-14121, 1999 | 733 | 1999 |
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles JC Brüning, J Winnay, S Bonner-Weir, SI Taylor, D Accili, CR Kahn Cell 88 (4), 561-572, 1997 | 704 | 1997 |
New perspectives on the microvasculature of the islets of Langerhans in the rat S Bonner-Weir, L Orci Diabetes 31 (10), 883-889, 1982 | 665 | 1982 |
Beta-cell adaptation and decompensation during the progression of diabetes. GC Weir, DR Laybutt, H Kaneto, S Bonner-Weir, A Sharma Diabetes 50 (suppl_1), S154, 2001 | 633 | 2001 |
Residual insulin production and pancreatic β-cell turnover after 50 years of diabetes: Joslin Medalist Study HA Keenan, JK Sun, J Levine, A Doria, LP Aiello, G Eisenbarth, ... Diabetes 59 (11), 2846-2853, 2010 | 624 | 2010 |
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. S Bonner-Weir, DF Trent, GC Weir The Journal of clinical investigation 71 (6), 1544-1553, 1983 | 620 | 1983 |
Compensatory growth of pancreatic β-cells in adult rats after short-term glucose infusion S Bonner-Weir, D Deery, JL Leahy, GC Weir Diabetes 38 (1), 49-53, 1989 | 602 | 1989 |
New sources of pancreatic β-cells S Bonner-Weir, GC Weir Nature biotechnology 23 (7), 857-861, 2005 | 597 | 2005 |