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Bram Brouwers
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Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised …
A Gastaldelli, K Cusi, LF Landó, R Bray, B Brouwers, Á Rodríguez
The lancet Diabetes & endocrinology 10 (6), 393-406, 2022
2172022
Effects of exercise training on intrahepatic lipid content in humans
B Brouwers, MKC Hesselink, P Schrauwen, VB Schrauwen-Hinderling
Diabetologia 59 (10), 2068-2079, 2016
1062016
Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox
S Daemen, A Gemmink, B Brouwers, RCR Meex, PR Huntjens, G Schaart, ...
Molecular metabolism 17, 71-81, 2018
952018
Long–echo time MR spectroscopy for skeletal muscle acetylcarnitine detection
L Lindeboom, CI Nabuurs, J Hoeks, B Brouwers, E Phielix, ME Kooi, ...
The Journal of clinical investigation 124 (11), 4915-4925, 2014
742014
Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans
R Mancilla, B Brouwers, VB Schrauwen‐Hinderling, MKC Hesselink, ...
Physiological Reports 8 (24), e14669, 2021
682021
Exercise training-induced effects on the abdominal subcutaneous adipose tissue phenotype in humans with obesity
R Stinkens, B Brouwers, JW Jocken, EE Blaak, KF Teunissen-Beekman, ...
Journal of Applied Physiology 125 (5), 1585-1593, 2018
662018
Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liver
B Brouwers, VB Schrauwen-Hinderling, T Jelenik, A Gemmink, LM Sparks, ...
American Journal of Physiology-Endocrinology and Metabolism 314 (2), E165-E173, 2018
642018
Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes
B Brouwers, VB Schrauwen-Hinderling, T Jelenik, A Gemmink, B Havekes, ...
Clinical Science 131 (15), 1905-1917, 2017
502017
Exercise response variations in skeletal muscle PCr recovery rate and insulin sensitivity relate to muscle epigenomic profiles in individuals with type 2 diabetes
NA Stephens, B Brouwers, AM Eroshkin, F Yi, HH Cornnell, C Meyer, ...
Diabetes Care 41 (10), 2245-2254, 2018
492018
Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance
SR Costford, B Brouwers, ME Hopf, LM Sparks, M Dispagna, AP Gomes, ...
Molecular metabolism 7, 1-11, 2018
482018
Acute exercise does not decrease liver fat in men with overweight or NAFLD
L Bilet, B Brouwers, PA Van Ewijk, MKC Hesselink, ME Kooi, ...
Scientific reports 5 (1), 9709, 2015
462015
Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5?
A Gemmink, S Daemen, B Brouwers, PR Huntjens, G Schaart, ...
The Journal of physiology 596 (5), 857-868, 2018
362018
Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes
LM Sparks, M Bosma, B Brouwers, T van de Weijer, L Bilet, G Schaart, ...
Diabetes 63 (5), 1583-1593, 2014
292014
The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity
F Vanweert, SC Boone, B Brouwers, DO Mook-Kanamori, R de Mutsert, ...
International Journal of Obesity 45 (7), 1510-1520, 2021
162021
Decoration of myocellular lipid droplets with perilipins as a marker for in vivo lipid droplet dynamics: A super-resolution microscopy study in trained athletes and insulin …
A Gemmink, S Daemen, B Brouwers, J Hoeks, G Schaart, K Knoops, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2021
152021
Elevated nicotinamide phosphoribosyl transferase in skeletal muscle augments exercise performance and mitochondrial respiratory capacity following exercise training
B Brouwers, NA Stephens, SR Costford, ME Hopf, JE Ayala, F Yi, H Xie, ...
Frontiers in physiology 9, 704, 2018
122018
An improvement in skeletal muscle mitochondrial capacity with short‐term aerobic training is associated with changes in Tribbles 1 expression
RB Vega, B Brouwers, SA Parsons, NA Stephens, MF Pino, A Hodges, ...
Physiological Reports 8 (12), e14416, 2020
112020
Mild exercise does not prevent atherosclerosis in APOE* 3‐Leiden. CETP mice or improve lipoprotein profile of men with obesity
W In het Panhuis, S Kooijman, B Brouwers, A Verhoeven, ACM Pronk, ...
Obesity 28, S93-S103, 2020
72020
Randomised clinical trial: Design of the SYNERGY‐NASH phase 2b trial to evaluate tirzepatide as a treatment for metabolic dysfunction‐associated steatohepatitis and …
R Vuppalanchi, R Loomba, AJ Sanyal, A Nikooie, Y Tang, DA Robins, ...
Alimentary Pharmacology & Therapeutics, 2024
12024
Incretin-based investigational therapies for the treatment of MASLD/MASH
B Brouwers, G Rao, Y Tang, Á Rodríguez, LC Glass, ML Hartman
Diabetes Research and Clinical Practice, 111675, 2024
12024
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