Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit ML Mohler, CE Bohl, A Jones, CC Coss, R Narayanan, Y He, DJ Hwang, ... Journal of medicinal chemistry 52 (12), 3597-3617, 2009 | 251 | 2009 |
Development of selective androgen receptor modulators (SARMs) R Narayanan, CC Coss, JT Dalton Molecular and cellular endocrinology 465, 134-142, 2018 | 240 | 2018 |
Selective androgen receptor modulators in preclinical and clinical development R Narayanan, ML Mohler, CE Bohl, DD Miller, JT Dalton Nuclear receptor signaling 6 (1), nrs. 06010, 2008 | 212 | 2008 |
Estrogen receptor-β-selective ligands alleviate high-fat diet-and ovariectomy-induced obesity in mice M Yepuru, J Eswaraka, JD Kearbey, CM Barrett, S Raghow, KA Veverka, ... Journal of Biological Chemistry 285 (41), 31292-31303, 2010 | 144 | 2010 |
Selective androgen receptor modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats JD Kearbey, W Gao, R Narayanan, SJ Fisher, D Wu, DD Miller, JT Dalton Pharmaceutical research 24, 328-335, 2007 | 137 | 2007 |
Steroidogenic enzyme AKR1C3 is a novel androgen receptor-selective coactivator that promotes prostate cancer growth M Yepuru, Z Wu, A Kulkarni, F Yin, CM Barrett, J Kim, MS Steiner, ... Clinical Cancer Research 19 (20), 5613-5625, 2013 | 129 | 2013 |
TMPRSS2:ERG Gene Fusion Predicts Subsequent Detection of Prostate Cancer in Patients With High-Grade Prostatic Intraepithelial Neoplasia K Park, JT Dalton, R Narayanan, CE Barbieri, ML Hancock, DG Bostwick, ... Journal of clinical oncology 32 (3), 206-211, 2014 | 127 | 2014 |
Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator R Narayanan, AA Adigun, DP Edwards, NL Weigel Molecular and cellular biology 25 (1), 264-277, 2005 | 126 | 2005 |
Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial: mesenchymal stem cell signaling R Narayanan, S Ahn, MD Cheney, M Yepuru, DD Miller, MS Steiner, ... PloS one 9 (7), e103202, 2014 | 97 | 2014 |
c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor α H Srinivas, DM Juroske, S Kalyankrishna, DD Cody, RE Price, XC Xu, ... Molecular and cellular biology 25 (3), 1054-1069, 2005 | 89 | 2005 |
Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer S Ponnusamy, CC Coss, T Thiyagarajan, K Watts, DJ Hwang, Y He, ... Cancer Research 77 (22), 6282-6298, 2017 | 86 | 2017 |
Steroidal androgens and nonsteroidal, tissue-selective androgen receptor modulator, S-22, regulate androgen receptor function through distinct genomic and nongenomic signaling … R Narayanan, CC Coss, M Yepuru, JD Kearbey, DD Miller, JT Dalton Molecular Endocrinology 22 (11), 2448-2465, 2008 | 85 | 2008 |
Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity R Narayanan, DP Edwards, NL Weigel Molecular and cellular biology, 2005 | 84 | 2005 |
Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy A Jones, DJ Hwang, R Narayanan, DD Miller, JT Dalton Endocrinology 151 (8), 3706-3719, 2010 | 82 | 2010 |
Estrogen regulates histone deacetylases to prevent cardiac hypertrophy A Pedram, M Razandi, R Narayanan, JT Dalton, TA McKinsey, ER Levin Molecular biology of the cell 24 (24), 3805-3818, 2013 | 79 | 2013 |
The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific R Narayanan, VAT Sepulveda, M Falzon, NL Weigel Journal of Biological Chemistry 279 (45), 47298-47310, 2004 | 71 | 2004 |
Androgen receptor: a complex therapeutic target for breast cancer R Narayanan, JT Dalton Cancers 8 (12), 108, 2016 | 70 | 2016 |
Therapeutic potential of the SARMs: revisiting the androgen receptor for drug discovery S Segal, R Narayanan, JT Dalton Expert Opinion on Investigational Drugs 15 (4), 377-387, 2006 | 70 | 2006 |
Structural and functional evidence for testosterone activation of GPRC6A in peripheral tissues M Pi, K Kapoor, Y Wu, R Ye, SE Senogles, SK Nishimoto, DJ Hwang, ... Molecular endocrinology 29 (12), 1759-1773, 2015 | 68 | 2015 |
MicroRNAs are mediators of androgen action in prostate and muscle R Narayanan, J Jiang, Y Gusev, A Jones, JD Kearbey, DD Miller, ... PloS one 5 (10), e13637, 2010 | 67 | 2010 |