关注
Christopher Wild
Christopher Wild
Dean, Health and Natural Sciences
在 sjcd.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Small molecule inhibitors targeting activator protein 1 (AP-1) miniperspective
N Ye, Y Ding, C Wild, Q Shen, J Zhou
Journal of medicinal chemistry 57 (16), 6930-6948, 2014
2492014
Direct activation of Bax protein for cancer therapy
Z Liu, Y Ding, N Ye, C Wild, H Chen, J Zhou
Medicinal research reviews 36 (2), 313-341, 2016
2252016
Discovery and development of natural product oridonin-inspired anticancer agents
Y Ding, C Ding, N Ye, Z Liu, EA Wold, H Chen, C Wild, Q Shen, J Zhou
European journal of medicinal chemistry 122, 102-117, 2016
1662016
Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility
C Ding, Y Zhang, H Chen, Z Yang, C Wild, L Chu, H Liu, Q Shen, J Zhou
Journal of medicinal chemistry 56 (12), 5048-5058, 2013
1112013
Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis
C Ding, Y Zhang, H Chen, Z Yang, C Wild, N Ye, CD Ester, A Xiong, ...
Journal of medicinal chemistry 56 (21), 8814-8825, 2013
772013
BH4 domain of Bcl-2 as a novel target for cancer therapy
Z Liu, C Wild, Y Ding, N Ye, H Chen, EA Wold, J Zhou
Drug discovery today 21 (6), 989-996, 2016
652016
Overcoming synthetic challenges of oridonin A-ring structural diversification: regio-and stereoselective installation of azides and 1, 2, 3-triazoles at the C-1, C-2, or C-3 …
C Ding, Y Zhang, H Chen, C Wild, T Wang, MA White, Q Shen, J Zhou
Organic letters 15 (14), 3718-3721, 2013
592013
Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3)
H Chen, Z Yang, C Ding, A Xiong, C Wild, L Wang, N Ye, G Cai, ...
European journal of medicinal chemistry 82, 195-203, 2014
572014
Recent Advances in the Discovery of Small Molecules Targeting Exchange Proteins Directly Activated by cAMP (EPAC) Miniperspective
H Chen, C Wild, X Zhou, N Ye, X Cheng, J Zhou
Journal of medicinal chemistry 57 (9), 3651-3665, 2014
522014
Targeting the 5-HT2C receptor in biological context and the current state of 5-HT2C receptor ligand development
EA Wold, CT Wild, KA Cunningham, J Zhou
Current topics in medicinal chemistry 19 (16), 1381-1398, 2019
492019
Structure–Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N′-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange …
N Ye, Y Zhu, H Chen, Z Liu, FC Mei, C Wild, H Chen, X Cheng, J Zhou
Journal of medicinal chemistry 58 (15), 6033-6047, 2015
482015
ent-Kaurane-based regio-and stereoselective inverse electron demand hetero-Diels–Alder reactions: synthesis of dihydropyran-fused diterpenoids
C Ding, L Wang, H Chen, C Wild, N Ye, Y Ding, T Wang, MA White, ...
Organic & biomolecular chemistry 12 (42), 8442-8452, 2014
482014
Efficient synthesis of ESI-09, a novel non-cyclic nucleotide EPAC antagonist
H Chen, C Ding, C Wild, H Liu, T Wang, MA White, X Cheng, J Zhou
Tetrahedron letters 54 (12), 1546-1549, 2013
382013
Allosteric modulation of G protein-coupled receptors: an emerging approach of drug discovery
C Wild, KA Cunningham, J Zhou
Austin journal of pharmacology and therapeutics 2 (1), 2014
352014
Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor
CT Wild, JM Miszkiel, EA Wold, CA Soto, C Ding, RM Hartley, MA White, ...
Journal of medicinal chemistry 62 (1), 288-305, 2018
322018
A combined bioinformatics and chemoinformatics approach for developing asymmetric bivalent AMPA receptor positive allosteric modulators as neuroprotective agents
H Chen, CZ Wang, C Ding, C Wild, B Copits, GT Swanson, KM Johnson, ...
ChemMedChem 8 (2), 226-230, 2013
312013
Intramolecular Cyclizations of Co2(CO)6-Complexed Propargyl Radicals: Synthesis of d,l- and meso-1,5-Cyclodecadiynes
GG Melikyan, C Wild, P Toure
Organometallics 27 (7), 1569-1581, 2008
282008
Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors
CT Wild, Y Zhu, Y Na, F Mei, MA Ynalvez, H Chen, X Cheng, J Zhou
ACS medicinal chemistry letters 7 (5), 460-464, 2016
222016
Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor-Positive Allosteric Modulators with Enhanced Drug-like Properties
EA Wold, EJ Garcia, CT Wild, JM Miszkiel, CA Soto, J Chen, K Pazdrak, ...
Journal of medicinal chemistry 63 (14), 7529-7544, 2020
192020
Carbon tether rigidity as a stereochemical tool directing intramolecular radical cyclizations
GG Melikyan, E Voorhees, C Wild, R Spencer, J Molnar
Tetrahedron Letters 51 (17), 2287-2290, 2010
162010
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