Bidirectional Eph–ephrin signaling during axon guidance J Egea, R Klein Trends in cell biology 17 (5), 230-238, 2007 | 499 | 2007 |
Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal … RM Soler, X Dolcet, M Encinas, J Egea, JR Bayascas, JX Comella Journal of neuroscience 19 (21), 9160-9169, 1999 | 236 | 1999 |
EphA4-dependent axon guidance is mediated by the RacGAP α2-chimaerin H Wegmeyer, J Egea, N Rabe, H Gezelius, A Filosa, A Enjin, ... Neuron 55 (5), 756-767, 2007 | 190 | 2007 |
FLRT2 and FLRT3 act as repulsive guidance cues for Unc5‐positive neurons S Yamagishi, F Hampel, K Hata, D Del Toro, M Schwark, E Kvachnina, ... The EMBO journal 30 (14), 2920-2933, 2011 | 177 | 2011 |
Activation of phosphatidylinositol 3‐kinase, but not extracellular‐regulated kinases, is necessary to mediate brain‐derived neurotrophic factor‐induced motoneuron survival X Dolcet, J Egea, RM Soler, D Martin‐Zanca, JX Comella Journal of neurochemistry 73 (2), 521-531, 1999 | 170 | 1999 |
Regulation of EphA4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function J Egea, UV Nissen, A Dufour, M Sahin, P Greer, K Kullander, ... Neuron 47 (4), 515-528, 2005 | 152 | 2005 |
Cytokines promote motoneuron survival through the Janus kinase-dependent activation of the phosphatidylinositol 3-kinase pathway X Dolcet, RM Soler, TW Gould, J Egea, RW Oppenheim, JX Comella Molecular and Cellular Neuroscience 18 (6), 619-631, 2001 | 130 | 2001 |
Calcium influx activates extracellular-regulated kinase/mitogen-activated protein kinase pathway through a calmodulin-sensitive mechanism in PC12 cells J Egea, C Espinet, JX Comella Journal of Biological Chemistry 274 (1), 75-85, 1999 | 113 | 1999 |
proBDNF is modified by advanced glycation end products in Alzheimer’s disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing C Fleitas, G Piñol-Ripoll, P Marfull, D Rocandio, I Ferrer, C Rampon, ... Molecular brain 11, 1-16, 2018 | 104 | 2018 |
FLRT3 is a Robo1-interacting protein that determines Netrin-1 attraction in developing axons E Leyva-Díaz, D del Toro, MJ Menal, S Cambray, R Susín, ... Current Biology 24 (5), 494-508, 2014 | 100 | 2014 |
Calmodulin is involved in membrane depolarization-mediated survival of motoneurons by phosphatidylinositol-3 kinase-and MAPK-independent pathways RM Soler, J Egea, GM Mintenig, C Sanz-Rodriguez, M Iglesias, ... Journal of Neuroscience 18 (4), 1230-1239, 1998 | 93 | 1998 |
Development of survival responsiveness to brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5, but not to nerve growth factor, in cultured motoneurons from … E Becker, RM Soler, VJ Yuste, E Gine, C Sanz-Rodrıguez, J Egea, ... Journal of Neuroscience 18 (19), 7903-7911, 1998 | 81 | 1998 |
Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation J Egea, C Erlacher, E Montanez, I Burtscher, S Yamagishi, M Heß, ... Genes & development 22 (23), 3349-3362, 2008 | 78 | 2008 |
Oxidative stress and neurodegenerative diseases: a neurotrophic approach C Espinet, H Gonzalo, C Fleitas, MJ Menal, J Egea Current drug targets 16 (1), 20-30, 2015 | 67 | 2015 |
Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca2+ and calmodulin J Egea, C Espinet, RM Soler, S Peiró, N Rocamora, JX Comella Molecular and Cellular Biology, 2000 | 67 | 2000 |
Neuronal survival induced by neurotrophins requires calmodulin J Egea, C Espinet, RM Soler, X Dolcet, VJ Yuste, M Encinas, M Iglesias, ... The Journal of Cell Biology 154 (3), 585-598, 2001 | 66 | 2001 |
Modulating Glypican4 suppresses tumorigenicity of embryonic stem cells while preserving self-renewal and pluripotency A Fico, A De Chevigny, J Egea, MR Bösl, H Cremer, F Maina, R Dono Stem Cells 30 (9), 1863-1874, 2012 | 60 | 2012 |
Differential, age‐dependent MEK‐ERK and PI3K‐Akt activation by insulin acting as a survival factor during embryonic retinal development T Chavarría, AI Valenciano, R Mayordomo, J Egea, JX Comella, ... Developmental neurobiology 67 (13), 1777-1788, 2007 | 48 | 2007 |
Calmodulin modulates mitogen‐activated protein kinase activation in response to membrane depolarization in PC12 cells J Egea, C Espinet, JX Comella Journal of neurochemistry 70 (6), 2554-2564, 1998 | 46 | 1998 |
Genetic analysis of EphA-dependent signaling mechanisms controlling topographic mapping in vivo A Dufour, J Egea, K Kullander, R Klein, P Vanderhaeghen Oxford University Press for The Company of Biologists Limited 133 (22), 4415 …, 2006 | 37 | 2006 |