关注
Melody Morris
Melody Morris
Novartis Institutes for Biomedical Research
在 novartis.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Logic-based models for the analysis of cell signaling networks
MK Morris, J Saez-Rodriguez, PK Sorger, DA Lauffenburger
Biochemistry 49 (15), 3216-3224, 2010
3942010
TORC1 inhibition enhances immune function and reduces infections in the elderly
JB Mannick, M Morris, HUP Hockey, G Roma, M Beibel, K Kulmatycki, ...
Science translational medicine 10 (449), eaaq1564, 2018
3702018
CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms
C Terfve, T Cokelaer, D Henriques, A MacNamara, E Goncalves, ...
BMC systems biology 6 (1), 133, 2012
2412012
Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli
MK Morris, J Saez-Rodriguez, DC Clarke, PK Sorger, DA Lauffenburger
PLoS Comput Biol 7 (3), e1001099-e1001099, 2011
1662011
Comparing signaling networks between normal and transformed hepatocytes using discrete logical models
J Saez-Rodriguez, LG Alexopoulos, MS Zhang, MK Morris, ...
Cancer research 71 (16), 5400-5411, 2011
1652011
Age-related gene expression signature in rats demonstrate early, late, and linear transcriptional changes from multiple tissues
T Shavlakadze, M Morris, J Fang, SX Wang, J Zhu, W Zhou, WT Herman, ...
Cell reports 28 (12), 3263-3273. e3, 2019
1332019
Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans
P Sebastiani, A Federico, M Morris, A Gurinovich, T Toshiko, A Bhutkar, ...
CELL-REPORTS-D-19-04587, 2019
532019
Systematic Analysis of Quantitative Logic Model Ensembles Predicts Drug Combination Effects on Cell Signaling Networks
MK Morris, DC Clarke, LC Osimiri, DA Lauffenburger
CPT: Pharmacometrics & Systems Pharmacology 5 (10), 544-553, 2016
382016
Phosphoproteomics in drug discovery
MK Morris, A Chi, IN Melas, LG Alexopoulos
Drug discovery today 19 (4), 425-432, 2014
372014
Normalization and Statistical Analysis of Multiplexed Bead-based Immunoassay Data Using Mixed-effects Modeling
DC Clarke, MK Morris, DA Lauffenburger
Molecular & Cellular Proteomics 12 (1), 245-262, 2013
292013
A serum protein signature of APOE genotypes in centenarians
P Sebastiani, S Monti, M Morris, A Gurinovich, T Toshiko, SL Andersen, ...
Aging cell 18 (6), e13023, 2019
262019
Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways
A Mitsos, IN Melas, MK Morris, J Saez-Rodriguez, DA Lauffenburger, ...
212012
Genes related to emphysema are enriched for ubiquitination pathways
S Stepaniants, IM Wang, Y Boie, J Mortimer, B Kennedy, M Elliott, ...
BMC pulmonary medicine 14 (1), 187, 2014
182014
Construction of cell type-specific logic models of signaling networks using CellNOpt
MK Morris, I Melas, J Saez-Rodriguez
Computational Toxicology, 179-214, 2013
132013
Querying quantitative logic models (Q2LM) to study intracellular signaling networks and cell‐cytokine interactions
MK Morris, Z Shriver, R Sasisekharan, DA Lauffenburger
Biotechnology journal 7 (3), 374-386, 2012
102012
Benchmarking network algorithms for contextualizing genes of interest
A Hill, S Gleim, F Kiefer, F Sigoillot, J Loureiro, J Jenkins, MK Morris
PLOS Computational Biology 15 (12), e1007403, 2019
82019
Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression
PJ Stivers, L Harmonay, A Hicks, H Mehmet, M Morris, GM Robinson, ...
PloS one 10 (12), 2015
52015
Methods of enhancing immune response
J Mannick, M Morris
US Patent 10,441,584, 2019
32019
Development of constrained fuzzy logic for modeling biological regulatory networks and predicting contextual therapeutic effects
MK Morris
Massachusetts Institute of Technology, 2012
12012
Identification of the ocular aging signature using RNA-Seq
A Banks, A Chen, N Li, N Vo, M Morris, Y Wang, C Ball, L Mansur
Investigative Ophthalmology & Visual Science 60 (9), 3428-3428, 2019
2019
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