Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade D Ajona, S Ortiz-Espinosa, T Lozano, F Exposito, A Calvo, K Valencia, ... Nature Cancer 1 (1), 75-85, 2020 | 93 | 2020 |
Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies C Palanca-Ballester, A Rodriguez-Casanova, S Torres, ... Cancers 13 (12), 3016, 2021 | 59 | 2021 |
Intratumoral combination therapy with poly (I: C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity C Anfray, F Mainini, E Digifico, A Maeda, M Sironi, M Erreni, A Anselmo, ... Journal for immunotherapy of cancer 9 (9), 2021 | 59 | 2021 |
miR-146a targets c-met and abolishes colorectal cancer liver metastasis AM Bleau, M Redrado, E Nistal-Villan, M Villalba, F Exposito, E Redin, ... Cancer letters 414, 257-267, 2018 | 53 | 2018 |
SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation E Redin, I Garmendia, T Lozano, D Serrano, Y Senent, M Redrado, ... Journal for immunotherapy of cancer 9 (3), 2021 | 50 | 2021 |
In vivo efficacy of bevacizumab-loaded albumin nanoparticles in the treatment of colorectal cancer I Luis de Redín, F Expósito, M Agüeros, M Collantes, I Peñuelas, ... Drug Delivery and Translational Research 10, 635-645, 2020 | 28 | 2020 |
Targeting of TMPRSS4 sensitizes lung cancer cells to chemotherapy by impairing the proliferation machinery F Exposito, M Villalba, M Redrado, AL de Aberasturi, C Cirauqui, E Redin, ... Cancer letters 453, 21-33, 2019 | 28 | 2019 |
Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer FJ de Miguel, C Gentile, WW Feng, SJ Silva, A Sankar, F Exposito, ... Cancer Cell 41 (8), 1516-1534. e9, 2023 | 18 | 2023 |
Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1 M Villalba, E Redin, F Exposito, MJ Pajares, C Sainz, D Hervas, ... Scientific Reports 9 (1), 15400, 2019 | 18 | 2019 |
TMPRSS4: a novel tumor prognostic indicator for the stratification of stage IA tumors and a liquid biopsy biomarker for NSCLC patients M Villalba, F Exposito, MJ Pajares, C Sainz, M Redrado, A Remirez, ... Journal of Clinical Medicine 8 (12), 2134, 2019 | 17 | 2019 |
Co-occurring alterations in multiple tumor suppressor genes are associated with worse outcomes in patients with EGFR-mutant lung cancer P Stockhammer, M Grant, A Wurtz, G Foggetti, F Expósito, J Gu, H Zhao, ... Journal of Thoracic Oncology 19 (2), 240-251, 2024 | 11 | 2024 |
YES1 is a druggable oncogenic target in SCLC E Redin, EM Garrido-Martin, K Valencia, M Redrado, JL Solorzano, ... Journal of Thoracic Oncology 17 (12), 1387-1403, 2022 | 11 | 2022 |
Circulating levels of the interferon-γ-regulated chemokines CXCL10/CXCL11, IL-6 and HGF predict outcome in metastatic renal cell carcinoma patients treated with antiangiogenic … E Esteban, F Exposito, G Crespo, J Lambea, A Pinto, J Puente, JA Arranz, ... Cancers 13 (11), 2849, 2021 | 11 | 2021 |
PTEN loss confers resistance to anti–PD-1 therapy in non–small cell lung cancer by increasing tumor infiltration of regulatory T cells F Exposito, M Redrado, M Houry, K Hastings, M Molero-Abraham, ... Cancer Research 83 (15), 2513-2526, 2023 | 8 | 2023 |
Development of biological tools to assess the role of TMPRSS4 and identification of novel tumor types with high expression of this prometastatic protein M Villalba, L Lopez, M Redrado, T Ruiz, AL de Aberasturi, N de la Roja, ... Universidad de Murcia. Departamento de Biología Celular e Histología, 2017 | 6 | 2017 |
Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma K Valencia, C Sainz, C Bertolo, G de Biurrun, J Agorreta, A Azpilikueta, ... Disease models & mechanisms 15 (1), dmm049137, 2022 | 5 | 2022 |
Cancer Cell-Intrinsic Alterations Associated with an Immunosuppressive Tumor Microenvironment and Resistance to Immunotherapy in Lung Cancer N Otegui, M Houry, I Arozarena, D Serrano, E Redin, F Exposito, S Leon, ... Cancers 15 (12), 3076, 2023 | 2 | 2023 |
PTEN loss confers resistance to anti-PD-1 therapy in NSCLC by increasing tumor infiltration of T regulatory cells F Exposito, M Redrado, M Houry, K Hastings, M Molero-Abraham, ... Cancer Research 83 (7_Supplement), 1124-1124, 2023 | 2 | 2023 |
P1. 03-24 TMPRSS4: A Novel Prognostic Biomarker and Therapeutic Target in NSCLC F Expósito, M Villalba, MJ Pajares, M Redrado, C Sainz, I Wistuba, ... Journal of Thoracic Oncology 13 (10), S521, 2018 | 2 | 2018 |
P2. 03-38 Identification of a Novel Synthetic Lethal Vulnerability in Non-Small Cell Lung Cancer by Co-Targeting TMPRSS4 and DDR1 E Redin, M Villalba, F Exposito, MJ Pajares, C Sainz, D Hervas, ... Journal of Thoracic Oncology 14 (10), S698-S699, 2019 | 1 | 2019 |