关注
Jacob Houghton
Jacob Houghton
Assistant Professor of Radiology, Stony Brook Cancer Centrr
在 stonybrookmedicine.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The future of aminoglycosides: the end or renaissance?
JL Houghton, KD Green, W Chen, S Garneau‐Tsodikova
ChemBioChem 11 (7), 880-902, 2010
2432010
AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism [S]
SL Pinkosky, S Filippov, RAK Srivastava, JC Hanselman, CD Bradshaw, ...
Journal of lipid research 54 (1), 134-151, 2013
2252013
18F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels–Alder Click Chemistry
JP Meyer, JL Houghton, P Kozlowski, D Abdel-Atti, T Reiner, ...
Bioconjugate chemistry 27 (2), 298-301, 2016
1512016
Site-specifically labeled CA19. 9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer
JL Houghton, BM Zeglis, D Abdel-Atti, R Aggeler, R Sawada, BJ Agnew, ...
Proceedings of the National Academy of Sciences 112 (52), 15850-15855, 2015
1142015
Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals
BM Zeglis, JL Houghton, MJ Evans, N Viola-Villegas, JS Lewis
Inorganic chemistry 53 (4), 1880-1899, 2014
1112014
Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry
JL Houghton, R Membreno, D Abdel-Atti, KM Cunanan, S Carlin, ...
Molecular cancer therapeutics 16 (1), 124-133, 2017
1002017
Pretargeted immuno-PET of pancreatic cancer: overcoming circulating antigen and internalized antibody to reduce radiation doses
JL Houghton, BM Zeglis, D Abdel-Atti, R Sawada, WW Scholz, JS Lewis
Journal of Nuclear Medicine 57 (3), 453-459, 2016
1002016
Exploring the substrate promiscuity of drug‐modifying enzymes for the chemoenzymatic generation of N‐acylated aminoglycosides
KD Green, W Chen, JL Houghton, M Fridman, S Garneau‐Tsodikova
ChemBioChem 11 (1), 119-126, 2010
872010
Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes
JL Houghton, KD Green, RE Pricer, AS Mayhoub, S Garneau-Tsodikova
Journal of antimicrobial chemotherapy 68 (4), 800-805, 2013
722013
Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis
JL Houghton, T Biswas, W Chen, OV Tsodikov, S Garneau‐Tsodikova
ChemBioChem 14 (16), 2127-2135, 2013
612013
The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI
T Biswas, JL Houghton, S Garneau‐Tsodikova, OV Tsodikov
Protein Science 21 (4), 520-530, 2012
602012
Challenges of pancreatic cancer
J Dimastromatteo, JL Houghton, JS Lewis, KA Kelly
The Cancer Journal 21 (3), 188-193, 2015
542015
Dual-modality imaging of prostate cancer with a fluorescent and radiogallium-labeled gastrin-releasing peptide receptor antagonist
H Zhang, P Desai, Y Koike, J Houghton, S Carlin, N Tandon, K Touijer, ...
Journal of Nuclear Medicine 58 (1), 29-35, 2017
482017
Tacrine-mefenamic acid hybrids for inhibition of acetylcholinesterase
JJ Bornstein, TJ Eckroat, JL Houghton, CK Jones, KD Green, ...
MedChemComm 2 (5), 406-412, 2011
442011
Preloading with Unlabeled CA19.9 Targeted Human Monoclonal Antibody Leads to Improved PET Imaging with 89Zr-5B1
JL Houghton, D Abdel-Atti, WW Scholz, JS Lewis
Molecular Pharmaceutics 14 (3), 908-915, 2017
422017
Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis
RE Pricer, JL Houghton, KD Green, AS Mayhoub, S Garneau-Tsodikova
Molecular BioSystems 8 (12), 3305-3313, 2012
412012
Tumor-specific Zr-89 immuno-PET imaging in a human bladder cancer model
FE Escorcia, JM Steckler, D Abdel-Atti, EW Price, SD Carlin, WW Scholz, ...
Molecular imaging and biology 20, 808-815, 2018
272018
ImmunoPET predicts response to Met-targeted radioligand therapy in models of pancreatic cancer resistant to Met kinase inhibitors
FE Escorcia, JL Houghton, D Abdel-Atti, PR Pereira, A Cho, NT Gutsche, ...
Theranostics 10 (1), 151, 2020
252020
Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT (4′)
VR Porter, KD Green, OE Zolova, JL Houghton, S Garneau-Tsodikova
Biochemical and biophysical research communications 403 (1), 85-90, 2010
212010
Current landscape in clinical pretargeted radioimmunoimaging and therapy
VIJ Jallinoja, JL Houghton
Journal of Nuclear Medicine 62 (9), 1200-1206, 2021
202021
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