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Iain S Forrest
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Machine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts
IS Forrest, BO Petrazzini, Á Duffy, JK Park, C Marquez-Luna, DM Jordan, ...
The Lancet 401 (10372), 215-225, 2023
662023
Population-based penetrance of deleterious clinical variants
IS Forrest, K Chaudhary, HMT Vy, BO Petrazzini, S Bafna, DM Jordan, ...
Jama 327 (4), 350-359, 2022
482022
Tissue-specific genetic features inform prediction of drug side effects in clinical trials
Á Duffy, M Verbanck, A Dobbyn, HH Won, JL Rein, IS Forrest, G Nadkarni, ...
Science advances 6 (37), eabb6242, 2020
402020
Genetic and phenotypic profiling of supranormal ejection fraction reveals decreased survival and underdiagnosed heart failure
IS Forrest, G Rocheleau, S Bafna, E Argulian, J Narula, P Natarajan, R Do
European journal of heart failure 24 (11), 2118-2127, 2022
242022
Coronary risk estimation based on clinical data in electronic health records
BO Petrazzini, K Chaudhary, C Márquez-Luna, IS Forrest, G Rocheleau, ...
Journal of the American College of Cardiology 79 (12), 1155-1166, 2022
232022
Non-invasive ventilation versus mechanical ventilation in hypoxemic patients with COVID-19
IS Forrest, SK Jaladanki, I Paranjpe, BS Glicksberg, GN Nadkarni, R Do
Infection 49 (5), 989-997, 2021
222021
Genome-wide polygenic risk score for retinopathy of type 2 diabetes
IS Forrest, K Chaudhary, I Paranjpe, HMT Vy, C Marquez-Luna, ...
Human Molecular Genetics 30 (10), 952-960, 2021
162021
Derivation and validation of genome-wide polygenic score for urinary tract stone diagnosis
I Paranjpe, N Tsao, R Judy, M Paranjpe, K Chaudhary, D Klarin, I Forrest, ...
Kidney international 98 (5), 1323-1330, 2020
162020
Dermestes maculatus: an intermediate-germ beetle model system for evo-devo
J Xiang, IS Forrest, L Pick
EvoDevo 6, 1-17, 2015
122015
A machine learning model identifies patients in need of autoimmune disease testing using electronic health records
IS Forrest, BO Petrazzini, Á Duffy, JK Park, AJ O’Neal, DM Jordan, ...
Nature Communications 14 (1), 2385, 2023
62023
Derivation and Validation of Genome‐Wide Polygenic Score for Ischemic Heart Failure
I Paranjpe, NL Tsao, JK De Freitas, R Judy, K Chaudhary, IS Forrest, ...
Journal of the American Heart Association 10 (22), e021916, 2021
52021
Genetic pleiotropy of ERCC6 loss‐of‐function and deleterious missense variants links retinal dystrophy, arrhythmia, and immunodeficiency in diverse ancestries
IS Forrest, K Chaudhary, HMT Vy, S Bafna, S Kim, HH Won, RJF Loos, ...
Human mutation 42 (8), 969-977, 2021
42021
Ancestrally and temporally diverse analysis of penetrance of clinical variants in 72,434 individuals
IS Forrest, K Chaudhary, HMT Vy, S Bafna, DM Jordan, G Rocheleau, ...
MedRxiv, 2021.03. 11.21253430, 2021
42021
Cholesterol contributes to risk, severity, and machine learning-driven diagnosis of Lyme disease
IS Forrest, AJ O’Neal, JHF Pedra, R Do
Clinical Infectious Diseases 77 (6), 839-847, 2023
32023
Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits
JK Park, S Bafna, IS Forrest, Á Duffy, C Marquez-Luna, BO Petrazzini, ...
Elife 12, e80560, 2023
22023
A tissue-level phenome-wide network map of colocalized genes and phenotypes in the UK Biobank
G Rocheleau, IS Forrest, Á Duffy, S Bafna, A Dobbyn, M Verbanck, ...
Communications Biology 5 (1), 849, 2022
22022
Exome sequence analysis identifies rare coding variants associated with a machine learning-based marker for coronary artery disease
BO Petrazzini, IS Forrest, G Rocheleau, HMT Vy, C Márquez-Luna, ...
Nature Genetics, 1-8, 2024
12024
Muesli intake may protect against coronary artery disease: Mendelian randomization on 13 dietary traits
JK Park, BO Petrazzini, S Bafna, Á Duffy, IS Forrest, HM Vy, ...
JACC: Advances 3 (4), 100888, 2024
12024
Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications
Á Duffy, BO Petrazzini, D Stein, JK Park, IS Forrest, K Gibson, HM Vy, ...
Nature Genetics 56 (1), 51-59, 2024
12024
Genome-first recall of healthy individuals by polygenic risk score reveals differences in coronary artery calcium
IS Forrest, L Chan, K Chaudhary, A Saha, HH Wen, CL Cepin, ...
American Heart Journal 250, 29-33, 2022
12022
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