Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes CE Nestor, R Ottaviano, J Reddington, D Sproul, D Reinhardt, D Dunican, ... Genome research 22 (3), 467-477, 2012 | 463 | 2012 |
The cis-regulatory dynamics of embryonic development at single-cell resolution DA Cusanovich, JP Reddington, DA Garfield, RM Daza, D Aghamirzaie, ... Nature 555 (7697), 538-542, 2018 | 342 | 2018 |
Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes JP Reddington, SM Perricone, CE Nestor, J Reichmann, NA Youngson, ... Genome biology 14, 1-17, 2013 | 261 | 2013 |
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline JA Hackett, JP Reddington, CE Nestor, DS Dunican, MR Branco, ... Development 139 (19), 3623-3632, 2012 | 173 | 2012 |
Non-canonical functions of the DNA methylome in gene regulation JP Reddington, S Pennings, RR Meehan Biochemical Journal 451 (1), 13-23, 2013 | 105 | 2013 |
The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development A Ruzov, E Savitskaya, JA Hackett, JP Reddington, A Prokhortchouk, ... Oxford University Press for The Company of Biologists Limited 136 (5), 729-738, 2009 | 73 | 2009 |
The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways A Ruzov, JA Hackett, A Prokhortchouk, JP Reddington, MJ Madej, ... Oxford University Press for The Company of Biologists Limited 136 (5), 723-727, 2009 | 63 | 2009 |
The multifunctional poly (A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important … M Brook, L McCracken, JP Reddington, ZL Lu, NA Morrice, NK Gray Biochemical Journal 441 (3), 803-816, 2012 | 59 | 2012 |
The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice J Reichmann, JP Reddington, D Best, D Read, R Öllinger, RR Meehan, ... Human molecular genetics 22 (9), 1791-1806, 2013 | 48 | 2013 |
Lineage-resolved enhancer and promoter usage during a time course of embryogenesis JP Reddington, DA Garfield, OM Sigalova, AK Calviello, ... Developmental cell 55 (5), 648-664. e9, 2020 | 46 | 2020 |
DNA methylation reprogramming in cancer: Does it act by re‐configuring the binding landscape of Polycomb repressive complexes? JP Reddington, D Sproul, RR Meehan Bioessays 36 (2), 134-140, 2014 | 44 | 2014 |
Apoptosis and DNA methylation HX Meng, JA Hackett, C Nestor, DS Dunican, M Madej, JP Reddington, ... Cancers 3 (2), 1798-1820, 2011 | 27 | 2011 |
The Role of Chromatin Accessibility in cis-Regulatory Evolution PC Peng, P Khoueiry, C Girardot, JP Reddington, DA Garfield, ... Genome biology and evolution 11 (7), 1813-1828, 2019 | 18 | 2019 |
Investigating 5-hydroxymethylcytosine (5hmC): the state of the art CE Nestor, JP Reddington, M Benson, RR Meehan Functional Analysis of DNA and Chromatin, 243-258, 2014 | 18 | 2014 |
The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection J Liu, RR Viales, P Khoueiry, JP Reddington, C Girardot, EEM Furlong, ... Genome Research 31 (9), 1573-1581, 2021 | 13 | 2021 |
scDALI: modeling allelic heterogeneity in single cells reveals context-specific genetic regulation T Heinen, S Secchia, JP Reddington, B Zhao, EEM Furlong, O Stegle Genome biology 23 (1), 8, 2022 | 11 | 2022 |
DNA methylation in mammalian and non-mammalian organisms M Moffat, JP Reddington, S Pennings, RR Meehan DNA METHYLATION–FROM GENOMICS TO TECHNOLOGY, 119, 2012 | 2 | 2012 |
scDALI: Modelling allelic heterogeneity of DNA accessibility in single-cells reveals context-specific genetic regulation T Heinen, S Secchia, J Reddington, B Zhao, EEM Furlong, O Stegle bioRxiv, 2021.03. 19.436142, 2021 | 1 | 2021 |
Evolutionary changes in DNA accessibility and sequence predict divergence of transcription factor binding and enhancer activity PC Peng, P Khoueiry, C Girardot, JP Reddington, DA Garfield, ... bioRxiv, 319046, 2018 | 1 | 2018 |
Putting muscle in DNA methylation JP Reddington, RR Meehan Cell Research 21 (11), 1531-1533, 2011 | 1 | 2011 |