Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases M Bucciantini, E Giannoni, F Chiti, F Baroni, L Formigli, J Zurdo, N Taddei, ... nature 416 (6880), 507-511, 2002 | 3025 | 2002 |
Anoikis molecular pathways and its role in cancer progression P Paoli, E Giannoni, P Chiarugi Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 3481-3498, 2013 | 1192 | 2013 |
Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness E Giannoni, F Bianchini, L Masieri, S Serni, E Torre, L Calorini, P Chiarugi Cancer research 70 (17), 6945-6956, 2010 | 660 | 2010 |
Anoikis: an emerging hallmark in health and diseases ML Taddei, E Giannoni, T Fiaschi, P Chiarugi The Journal of pathology 226 (2), 380-393, 2012 | 630 | 2012 |
Anoikis: a necessary death program for anchorage-dependent cells P Chiarugi, E Giannoni Biochemical pharmacology 76 (11), 1352-1364, 2008 | 610 | 2008 |
Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay T Fiaschi, A Marini, E Giannoni, ML Taddei, P Gandellini, A De Donatis, ... Cancer research 72 (19), 5130-5140, 2012 | 528 | 2012 |
Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion P Chiarugi, G Pani, E Giannoni, L Taddei, R Colavitti, G Raugei, ... The Journal of cell biology 161 (5), 933-944, 2003 | 524 | 2003 |
Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth E Giannoni, F Buricchi, G Raugei, G Ramponi, P Chiarugi Molecular and cellular biology 25 (15), 6391-6403, 2005 | 521 | 2005 |
Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression G Comito, E Giannoni, CP Segura, P Barcellos-de-Souza, MR Raspollini, ... Oncogene 33 (19), 2423-2431, 2014 | 519 | 2014 |
Lactate: a metabolic driver in the tumour landscape L Ippolito, A Morandi, E Giannoni, P Chiarugi Trends in biochemical sciences 44 (2), 153-166, 2019 | 334 | 2019 |
Microenvironment and tumor cell plasticity: an easy way out ML Taddei, E Giannoni, G Comito, P Chiarugi Cancer letters 341 (1), 80-96, 2013 | 304 | 2013 |
Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case S Ventura, J Zurdo, S Narayanan, M Parreño, R Mangues, B Reif, F Chiti, ... Proceedings of the National Academy of Sciences 101 (19), 7258-7263, 2004 | 290 | 2004 |
EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy E Giannoni, M Parri, P Chiarugi Antioxidants & redox signaling 16 (11), 1248-1263, 2012 | 231 | 2012 |
Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness E Giannoni, F Bianchini, L Calorini, P Chiarugi Antioxidants & redox signaling 14 (12), 2361-2371, 2011 | 229 | 2011 |
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernández-Pérez, C Isella, ... Cell metabolism 28 (6), 848-865. e6, 2018 | 222 | 2018 |
Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation P Chiarugi, T Fiaschi, ML Taddei, D Talini, E Giannoni, G Raugei, ... Journal of Biological Chemistry 276 (36), 33478-33487, 2001 | 214 | 2001 |
Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer L Ippolito, A Morandi, ML Taddei, M Parri, G Comito, A Iscaro, ... Oncogene 38 (27), 5339-5355, 2019 | 201 | 2019 |
The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy M Lanciotti, L Masieri, MR Raspollini, A Minervini, A Mari, G Comito, ... BioMed research international 2014 (1), 486798, 2014 | 180 | 2014 |
HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells G Comito, M Calvani, E Giannoni, F Bianchini, L Calorini, E Torre, ... Free Radical Biology and Medicine 51 (4), 893-904, 2011 | 178 | 2011 |
Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival E Giannoni, F Buricchi, G Grimaldi, M Parri, F Cialdai, ML Taddei, ... Cell Death & Differentiation 15 (5), 867-878, 2008 | 168 | 2008 |