The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes TP Gu, F Guo, H Yang, HP Wu, GF Xu, W Liu, ZG Xie, L Shi, X He, S Jin, ... Nature 477 (7366), 606-610, 2011 | 1303 | 2011 |
Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote F Guo, X Li, D Liang, T Li, P Zhu, H Guo, X Wu, L Wen, TP Gu, B Hu, ... Cell stem cell 15 (4), 447-459, 2014 | 420 | 2014 |
Vitamin C modulates TET1 function during somatic cell reprogramming J Chen, L Guo, L Zhang, H Wu, J Yang, H Liu, X Wang, X Hu, T Gu, ... Nature genetics 45 (12), 1504-1509, 2013 | 345 | 2013 |
DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells T Gu, X Lin, SM Cullen, M Luo, M Jeong, M Estecio, J Shen, S Hardikar, ... Genome biology 19, 1-15, 2018 | 155 | 2018 |
Isoform switch of TET1 regulates DNA demethylation and mouse development W Zhang, W Xia, Q Wang, AJ Towers, J Chen, R Gao, Y Zhang, C Yen, ... Molecular cell 64 (6), 1062-1073, 2016 | 122 | 2016 |
Gadd45a promotes DNA demethylation through TDG Z Li, TP Gu, AR Weber, JZ Shen, BZ Li, ZG Xie, R Yin, F Guo, X Liu, ... Nucleic acids research 43 (8), 3986-3997, 2015 | 111 | 2015 |
Uracil-DNA glycosylase UNG promotes Tet-mediated DNA demethylation JH Xue, GF Xu, TP Gu, GD Chen, BB Han, ZM Xu, M Bjørås, HE Krokan, ... Journal of Biological Chemistry 291 (2), 731-738, 2016 | 41 | 2016 |
Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions L Xu, X Liu, F Peng, W Zhang, L Zheng, Y Ding, T Gu, K Lv, J Wang, ... Nature cell biology 22 (10), 1162-1169, 2020 | 37 | 2020 |
The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development T Gu, D Hao, J Woo, TW Huang, L Guo, X Lin, AG Guzman, A Tovy, ... Nature genetics 54 (5), 625-636, 2022 | 35 | 2022 |
Essential role of a trypanosome U4-specific Sm core protein in small nuclear ribonucleoprotein assembly and splicing N Jaé, P Wang, T Gu, M Hühn, Z Palfi, H Urlaub, A Bindereif Eukaryotic cell 9 (3), 379-386, 2010 | 25 | 2010 |
The push and pull of DNA methylation T Gu, MA Goodell Science 372 (6538), 128-129, 2021 | 19 | 2021 |
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis A Tovy, JM Reyes, L Zhang, YH Huang, C Rosas, AC Daquinag, ... Elife 11, e72359, 2022 | 16 | 2022 |
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells R Ramabadran, JH Wang, JM Reyes, AG Guzman, S Gupta, C Rosas, ... Nature cell biology 25 (4), 528-539, 2023 | 11 | 2023 |
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation CW Chen, L Zhang, R Dutta, A Niroula, PG Miller, CJ Gibson, AG Bick, ... Cell Stem Cell 30 (11), 1503-1519. e8, 2023 | 6 | 2023 |
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation CW Chen, L Zhang, R Dutta, A Niroula, PG Miller, CJ Gibson, AG Bick, ... Cell stem cell 31 (2), 275-277, 2024 | | 2024 |
Clonal Competition: Cisplatin Treatment Drives Dominance of TP53-over Tet2-Mutant Stem Cell Clones K Wohlan, L Brunetti, JI Hsu, KA Matatall, RL Murdaugh, L Zhang, ... Blood 140 (Supplement 1), 8590-8591, 2022 | | 2022 |