Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells Y Zeng, EJ Wagner, BR Cullen Molecular cell 9 (6), 1327-1333, 2002 | 1298 | 2002 |
Understanding the language of Lys36 methylation at histone H3 EJ Wagner, PB Carpenter Nature reviews Molecular cell biology 13 (2), 115-126, 2012 | 993 | 2012 |
Metabolism and regulation of canonical histone mRNAs: life without a poly (A) tail WF Marzluff, EJ Wagner, RJ Duronio Nature Reviews Genetics 9 (11), 843-854, 2008 | 875 | 2008 |
Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types Z Xia, LA Donehower, TA Cooper, JR Neilson, DA Wheeler, EJ Wagner, ... Nature communications 5 (1), 5274, 2014 | 551 | 2014 |
Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay MC Wollerton, C Gooding, EJ Wagner, MA Garcia-Blanco, CWJ Smith Molecular cell 13 (1), 91-100, 2004 | 487 | 2004 |
Polypyrimidine tract binding protein antagonizes exon definition EJ Wagner, MA Garcia-Blanco Molecular and cellular biology, 2001 | 482 | 2001 |
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression CP Masamha, Z Xia, J Yang, TR Albrecht, M Li, AB Shyu, W Li, EJ Wagner Nature 510 (7505), 412-416, 2014 | 404 | 2014 |
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ... Cell 185 (14), 2559-2575. e28, 2022 | 258 | 2022 |
An intronic splicing silencer causes skipping of the IIIb exon of fibroblast growth factor receptor 2 through involvement of polypyrimidine tract binding protein RP Carstens, EJ Wagner, MA Garcia-Blanco Molecular and cellular biology, 2000 | 189 | 2000 |
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 184 | 2019 |
RNAi-mediated PTB depletion leads to enhanced exon definition EJ Wagner, MA Garcia-Blanco Molecular cell 10 (4), 943-949, 2002 | 181 | 2002 |
Integrator regulates transcriptional initiation and pause release following activation A Gardini, D Baillat, M Cesaroni, D Hu, JM Marinis, EJ Wagner, MA Lazar, ... Molecular cell 56 (1), 128-139, 2014 | 177 | 2014 |
The integrator complex attenuates promoter-proximal transcription at protein-coding genes ND Elrod, T Henriques, KL Huang, DC Tatomer, JE Wilusz, EJ Wagner, ... Molecular cell 76 (5), 738-752. e7, 2019 | 164 | 2019 |
3′ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk HJ Park, P Ji, S Kim, Z Xia, B Rodriguez, L Li, J Su, K Chen, CP Masamha, ... Nature genetics 50 (6), 783-789, 2018 | 147 | 2018 |
Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation RT Richardson, OM Alekseev, G Grossman, EE Widgren, R Thresher, ... Journal of Biological Chemistry 281 (30), 21526-21534, 2006 | 138 | 2006 |
The Integrator complex cleaves nascent mRNAs to attenuate transcription DC Tatomer, ND Elrod, D Liang, MS Xiao, JZ Jiang, M Jonathan, ... Genes & development 33 (21-22), 1525-1538, 2019 | 127 | 2019 |
Integrator recruits protein phosphatase 2A to prevent pause release and facilitate transcription termination KL Huang, D Jee, CB Stein, ND Elrod, T Henriques, LG Mascibroda, ... Molecular cell 80 (2), 345-358. e9, 2020 | 119 | 2020 |
A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100 Z Dominski, X Yang, M Purdy, EJ Wagner, WF Marzluff Molecular and cellular biology 25 (4), 1489-1500, 2005 | 116 | 2005 |
An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability L Li, KL Huang, Y Gao, Y Cui, G Wang, ND Elrod, Y Li, YE Chen, P Ji, ... Nature genetics 53 (7), 994-1005, 2021 | 113 | 2021 |
Knockdown of SLBP results in nuclear retention of histone mRNA KD Sullivan, TE Mullen, WF Marzluff, EJ Wagner Rna 15 (3), 459-472, 2009 | 106 | 2009 |