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Kannan V Manian
Kannan V Manian
Postdoctoral Research Associate, Ocular Genomics Institute, Harvard Medical School
在 MEEI.HARVARD.EDU 的电子邮件经过验证
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3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration
KV Manian, CA Galloway, S Dalvi, AA Emanuel, JA Mereness, W Black, ...
Cell Stem Cell 28 (5), 846-862. e8, 2021
432021
Systematic evaluation of markers used for the identification of human induced pluripotent stem cells
SP Bharathan, KV Manian, SMM Aalam, D Palani, PA Deshpande, ...
Biology open 6 (1), 100-108, 2017
402017
A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface
C Tang, J Han, S Dalvi, KV Manian, L Winschel, S Volland, CA Soto, ...
Communications Biology 4 (1), 161, 2021
302021
Generation of an integration-free iPSC line (CSCRi005-A) from erythroid progenitor cells of a healthy Indian male individual
KV Manian, SP Bharathan, M Maddali, VM Srivastava, A Srivastava, ...
Stem Cell Research 29, 148-151, 2018
72018
Derivation of clinical-grade induced pluripotent stem cell lines from erythroid progenitor cells in xenofree conditions
G Singh, KV Manian, C Premkumar, A Srivastava, D Daniel, ...
Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, 775-789, 2021
32021
Understanding the molecular basis of heterogeneity in induced pluripotent stem cells
KV Manian, SMM Aalam, SP Bharathan, A Srivastava, SR Velayudhan
Cellular Reprogramming (Formerly" Cloning and Stem Cells") 17 (6), 427-440, 2015
32015
Organic contaminants and phytoremediation: a critical appraisal
RP Thomas, J Paul, V Vinod, KV Manian
Bioenergy Crops, 18-36, 2022
22022
Deep mutational scanning reveals the pathogenicity and structural constraints of a comprehensive set of rhodopsin missense variants
KV Manian, E Hennessey, H Eun, H Scott, X Yang, DE Root, EA Pierce, ...
Investigative Ophthalmology & Visual Science 65 (7), 457-457, 2024
2024
Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells.
BA Apte, A Grenell, C Singh, M Raju, A Wolk, S Dalvi, GF Jang, J Crabb, ...
2024
Base editing approach for in vitro and in vivo evaluation of therapeutic targets in USH2A
KV Manian, Y Tachida, E Hennessey, R Butcher, EA Pierce, DR Liu, Q Liu, ...
Investigative Ophthalmology & Visual Science 64 (8), 1912-1912, 2023
2023
Epidemics and Pandemics: The Kerala Model
RP Thomas, S Raj, V Vinod, KV Manian
Pandemics and Global Health, 2021
2021
Cell-autonomous RPE dysfunction is sufficient to instigate CC atrophy and CNV in an iPSC model of Macular Degeneration
KV Manian, S Dalvi, CA Galloway, C Soto, L Winschel, Y Li, DSW Benoit, ...
Investigative Ophthalmology & Visual Science 61 (7), 3809-3809, 2020
2020
Dysregulation of MMP2/MMP9 activity by both local (RPE, vasculature) and systemic (serum) factors promotes macular-degeneration-relevant pathological changes in iPSC-derived …
KV Manian, S Dalvi, CA Galloway, L Winschel, A Jain, C Soto, R Singh
Investigative Ophthalmology & Visual Science 60 (9), 1227-1227, 2019
2019
Identification of Stable OCT4 (+) NANOG (-) State in Somatic Cell Reprogramming
SMM Aalam, KV Manian, SP Bharathan, T Mayuranathan, ...
Cellular Reprogramming 18 (6), 367-368, 2016
2016
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