3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration KV Manian, CA Galloway, S Dalvi, AA Emanuel, JA Mereness, W Black, ... Cell Stem Cell 28 (5), 846-862. e8, 2021 | 43 | 2021 |
Systematic evaluation of markers used for the identification of human induced pluripotent stem cells SP Bharathan, KV Manian, SMM Aalam, D Palani, PA Deshpande, ... Biology open 6 (1), 100-108, 2017 | 40 | 2017 |
A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface C Tang, J Han, S Dalvi, KV Manian, L Winschel, S Volland, CA Soto, ... Communications Biology 4 (1), 161, 2021 | 30 | 2021 |
Generation of an integration-free iPSC line (CSCRi005-A) from erythroid progenitor cells of a healthy Indian male individual KV Manian, SP Bharathan, M Maddali, VM Srivastava, A Srivastava, ... Stem Cell Research 29, 148-151, 2018 | 7 | 2018 |
Derivation of clinical-grade induced pluripotent stem cell lines from erythroid progenitor cells in xenofree conditions G Singh, KV Manian, C Premkumar, A Srivastava, D Daniel, ... Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, 775-789, 2021 | 3 | 2021 |
Understanding the molecular basis of heterogeneity in induced pluripotent stem cells KV Manian, SMM Aalam, SP Bharathan, A Srivastava, SR Velayudhan Cellular Reprogramming (Formerly" Cloning and Stem Cells") 17 (6), 427-440, 2015 | 3 | 2015 |
Organic contaminants and phytoremediation: a critical appraisal RP Thomas, J Paul, V Vinod, KV Manian Bioenergy Crops, 18-36, 2022 | 2 | 2022 |
Deep mutational scanning reveals the pathogenicity and structural constraints of a comprehensive set of rhodopsin missense variants KV Manian, E Hennessey, H Eun, H Scott, X Yang, DE Root, EA Pierce, ... Investigative Ophthalmology & Visual Science 65 (7), 457-457, 2024 | | 2024 |
Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells. BA Apte, A Grenell, C Singh, M Raju, A Wolk, S Dalvi, GF Jang, J Crabb, ... | | 2024 |
Base editing approach for in vitro and in vivo evaluation of therapeutic targets in USH2A KV Manian, Y Tachida, E Hennessey, R Butcher, EA Pierce, DR Liu, Q Liu, ... Investigative Ophthalmology & Visual Science 64 (8), 1912-1912, 2023 | | 2023 |
Epidemics and Pandemics: The Kerala Model RP Thomas, S Raj, V Vinod, KV Manian Pandemics and Global Health, 2021 | | 2021 |
Cell-autonomous RPE dysfunction is sufficient to instigate CC atrophy and CNV in an iPSC model of Macular Degeneration KV Manian, S Dalvi, CA Galloway, C Soto, L Winschel, Y Li, DSW Benoit, ... Investigative Ophthalmology & Visual Science 61 (7), 3809-3809, 2020 | | 2020 |
Dysregulation of MMP2/MMP9 activity by both local (RPE, vasculature) and systemic (serum) factors promotes macular-degeneration-relevant pathological changes in iPSC-derived … KV Manian, S Dalvi, CA Galloway, L Winschel, A Jain, C Soto, R Singh Investigative Ophthalmology & Visual Science 60 (9), 1227-1227, 2019 | | 2019 |
Identification of Stable OCT4 (+) NANOG (-) State in Somatic Cell Reprogramming SMM Aalam, KV Manian, SP Bharathan, T Mayuranathan, ... Cellular Reprogramming 18 (6), 367-368, 2016 | | 2016 |