BCG vaccination protects against experimental viral infection in humans through the induction of cytokines associated with trained immunity RJW Arts, SJ Moorlag, B Novakovic, Y Li, SY Wang, M Oosting, V Kumar, ... Cell host & microbe 23 (1), 89-100. e5, 2018 | 1097 | 2018 |
Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ... Cell metabolism 24 (6), 807-819, 2016 | 707 | 2016 |
Metabolic induction of trained immunity through the mevalonate pathway S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der Heijden, ... Cell 172 (1), 135-146. e9, 2018 | 605 | 2018 |
β-Glucan reverses the epigenetic state of LPS-induced immunological tolerance B Novakovic, E Habibi, SY Wang, RJW Arts, R Davar, W Megchelenbrink, ... Cell 167 (5), 1354-1368. e14, 2016 | 560 | 2016 |
Trained immunity, tolerance, priming and differentiation: distinct immunological processes M Divangahi, P Aaby, SA Khader, LB Barreiro, S Bekkering, T Chavakis, ... Nature immunology 22 (1), 2-6, 2021 | 384 | 2021 |
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome M Ollikainen, KR Smith, EJH Joo, HK Ng, R Andronikos, B Novakovic, ... Human molecular genetics 19 (21), 4176-4188, 2010 | 359 | 2010 |
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface B Novakovic, M Sibson, HK Ng, U Manuelpillai, V Rakyan, T Down, ... Journal of Biological Chemistry 284 (22), 14838-14848, 2009 | 318 | 2009 |
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence L Gordon, JE Joo, JE Powell, M Ollikainen, B Novakovic, X Li, ... Genome research 22 (8), 1395-1406, 2012 | 309 | 2012 |
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ... Cell metabolism 29 (1), 211-220. e5, 2019 | 290 | 2019 |
Intrauterine programming of obesity and type 2 diabetes DS Fernandez-Twinn, L Hjort, B Novakovic, SE Ozanne, R Saffery Diabetologia 62, 1789-1801, 2019 | 231 | 2019 |
BCG vaccination induces long-term functional reprogramming of human neutrophils SJ Moorlag, YA Rodriguez-Rosales, J Gillard, S Fanucchi, K Theunissen, ... Cell reports 33 (7), 2020 | 204 | 2020 |
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors B Novakovic, RK Yuen, L Gordon, MS Penaherrera, A Sharkey, A Moffett, ... BMC genomics 12, 1-14, 2011 | 202 | 2011 |
β-Glucan induces protective trained immunity against Mycobacterium tuberculosis infection: a key role for IL-1 SJ Moorlag, N Khan, B Novakovic, E Kaufmann, T Jansen, R van Crevel, ... Cell reports 31 (7), 2020 | 192 | 2020 |
Sexual dimorphism in innate immunity: the role of sex hormones and epigenetics R Shepherd, AS Cheung, K Pang, R Saffery, B Novakovic Frontiers in immunology 11, 604000, 2021 | 183 | 2021 |
Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway TO Crişan, MCP Cleophas, B Novakovic, K Erler, FL van de Veerdonk, ... Proceedings of the National Academy of Sciences 114 (21), 5485-5490, 2017 | 150 | 2017 |
Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy B Novakovic, J Ryan, N Pereira, B Boughton, JM Craig, R Saffery Epigenetics 9 (3), 377-386, 2014 | 148 | 2014 |
The ever growing complexity of placental epigenetics–role in adverse pregnancy outcomes and fetal programming B Novakovic, R Saffery Placenta 33 (12), 959-970, 2012 | 145 | 2012 |
Epigenetic regulation of human placental function and pregnancy outcome: considerations for causal inference V Januar, G Desoye, B Novakovic, S Cvitic, R Saffery American journal of obstetrics and gynecology 213 (4), S182-S196, 2015 | 128 | 2015 |
Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood B Novakovic, S Lewis, J Halliday, J Kennedy, DP Burgner, A Czajko, ... Nature Communications 10 (1), 3922, 2019 | 115 | 2019 |
Treatment with statins does not revert trained immunity in patients with familial hypercholesterolemia S Bekkering, LCA Stiekema, SB Moens, SL Verweij, B Novakovic, ... Cell metabolism 30 (1), 1-2, 2019 | 113 | 2019 |