Origins of lifetime health around the time of conception: causes and consequences TP Fleming, AJ Watkins, MA Velazquez, JC Mathers, AM Prentice, ... The Lancet 391 (10132), 1842-1852, 2018 | 997 | 2018 |
Adolescence and the next generation GC Patton, CA Olsson, V Skirbekk, R Saffery, ME Wlodek, PS Azzopardi, ... Nature 554 (7693), 458-466, 2018 | 385 | 2018 |
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome M Ollikainen, KR Smith, EJH Joo, HK Ng, R Andronikos, B Novakovic, ... Human molecular genetics 19 (21), 4176-4188, 2010 | 358 | 2010 |
A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA D Sart, MR Cancilla, E Earle, J Mao, R Saffery, KM Tainton, P Kalitsis, ... Nature genetics 16 (2), 144-153, 1997 | 353 | 1997 |
Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere LH Wong, KH Brettingham-Moore, L Chan, JM Quach, MA Anderson, ... Genome research 17 (8), 1146-1160, 2007 | 336 | 2007 |
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface B Novakovic, M Sibson, HK Ng, U Manuelpillai, V Rakyan, T Down, ... Journal of Biological Chemistry 284 (22), 14838-14848, 2009 | 317 | 2009 |
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence L Gordon, JE Joo, JE Powell, M Ollikainen, B Novakovic, X Li, ... Genome research 22 (8), 1395-1406, 2012 | 309 | 2012 |
Prospects for epigenetic epidemiology DL Foley, JM Craig, R Morley, CJ Olsson, T Dwyer, K Smith, R Saffery American journal of epidemiology 169 (4), 389-400, 2009 | 302 | 2009 |
Active transcription and essential role of RNA polymerase II at the centromere during mitosis FL Chan, OJ Marshall, R Saffery, BO Won Kim, E Earle, KHA Choo, ... Proceedings of the National Academy of Sciences 109 (6), 1979-1984, 2012 | 292 | 2012 |
Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights DF Hudson, KJ Fowler, E Earle, R Saffery, P Kalitsis, H Trowell, J Hill, ... The Journal of cell biology 141 (2), 309-319, 1998 | 292 | 1998 |
Human transgenerational responses to early-life experience: potential impact on development, health and biomedical research M Pembrey, R Saffery, LO Bygren Journal of medical genetics 51 (9), 563-572, 2014 | 287 | 2014 |
Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies LE Hogan, JA Meyer, J Yang, J Wang, N Wong, W Yang, G Condos, ... Blood, The Journal of the American Society of Hematology 118 (19), 5218-5226, 2011 | 284 | 2011 |
Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the … K Silventoinen, A Jelenkovic, R Sund, YM Hur, Y Yokoyama, C Honda, ... The American journal of clinical nutrition 104 (2), 371-379, 2016 | 234 | 2016 |
Intrauterine programming of obesity and type 2 diabetes DS Fernandez-Twinn, L Hjort, B Novakovic, SE Ozanne, R Saffery Diabetologia 62, 1789-1801, 2019 | 230 | 2019 |
Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of … D Martino, YJ Loke, L Gordon, M Ollikainen, MN Cruickshank, R Saffery, ... Genome biology 14, 1-14, 2013 | 217 | 2013 |
Machine learning SNP based prediction for precision medicine DSW Ho, W Schierding, M Wake, R Saffery, J O’Sullivan Frontiers in genetics 10, 267, 2019 | 216 | 2019 |
Host genetic control of the oral microbiome in health and disease A Gomez, JL Espinoza, DM Harkins, P Leong, R Saffery, M Bockmann, ... Cell host & microbe 22 (3), 269-278. e3, 2017 | 214 | 2017 |
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic … JT Huse, M Snuderl, DTW Jones, CD Brathwaite, N Altman, E Lavi, ... Acta neuropathologica 133, 417-429, 2017 | 213 | 2017 |
Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts A Jelenkovic, R Sund, YM Hur, Y Yokoyama, JB Hjelmborg, S Möller, ... Scientific reports 6 (1), 28496, 2016 | 209 | 2016 |
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors B Novakovic, RK Yuen, L Gordon, MS Penaherrera, A Sharkey, A Moffett, ... BMC genomics 12, 1-14, 2011 | 202 | 2011 |