Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase–Akt/PKB survival pathway GA Ruiter, SF Zerp, H Bartelink, WJ van Blitterswijk, M Verheij Anti-cancer drugs 14 (2), 167-173, 2003 | 261 | 2003 |
Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis GA Ruiter, SF Zerp, H Bartelink, WJ van Blitterswijk, M Verheij Cancer research 59 (10), 2457-2463, 1999 | 225 | 1999 |
Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma. A van Elsas, SF Zerp, S van der Flier, KM Krüse, C Aarnoudse, ... The American journal of pathology 149 (3), 883, 1996 | 191 | 1996 |
Separate structural elements within internal transcribed spacer 1 of Saccharomyces cerevisiae precursor ribosomal RNA direct the formation of 17S and 26S rRNA RW van Nues, JMJ Rientjes, CAFM van der Sande, SF Zerp, C Sluiter, ... Nucleic acids research 22 (6), 912-919, 1994 | 175 | 1994 |
In vivo imaging of radiation-induced apoptosis in follicular lymphoma patients RLM Haas, D de Jong, RAV Olmos, CA Hoefnagel, I van Den Heuvel, ... International Journal of Radiation Oncology* Biology* Physics 59 (3), 782-787, 2004 | 157 | 2004 |
The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis M Verheij, GA Ruiter, SF Zerp, WJ van Blitterswijk, Z Fuks, ... Radiotherapy and oncology 47 (3), 225-232, 1998 | 143 | 1998 |
Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis GA Ruiter, M Verheij, SF Zerp, WJ van Blitterswijk International Journal of Radiation Oncology* Biology* Physics 49 (2), 415-419, 2001 | 130 | 2001 |
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis SF Zerp, A Van Elsas, LTC Peltenburg, PI Schrier British journal of cancer 79 (5), 921-926, 1999 | 117 | 1999 |
Prognostic factors in transitional cell cancer of the bladder: an emerging role for Bcl-2 and p53 F Ong, LMF Moonen, MPW Gallee, C ten Bosch, SF Zerp, AAM Hart, ... Radiotherapy and Oncology 61 (2), 169-175, 2001 | 109 | 2001 |
Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin-and cholesterol-deficiency in … AH Van der Luit, M Budde, S Zerp, W Caan, JB Klarenbeek, M Verheij, ... Biochemical Journal 401 (2), 541-549, 2007 | 104 | 2007 |
Growth-related expression of ribosomal protein genes in Saccharomyces cerevisiae LS Kraakman, G Griffioen, S Zerp, P Groeneveld, JM Thevelein, ... Molecular and General Genetics MGG 239, 196-204, 1993 | 87 | 1993 |
AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis SF Zerp, R Stoter, G Kuipers, D Yang, ME Lippman, WJ van Blitterswijk, ... Radiation Oncology 4, 1-10, 2009 | 72 | 2009 |
N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx RJ Veldman, S Zerp, WJ Van Blitterswijk, M Verheij British journal of cancer 90 (4), 917-925, 2004 | 64 | 2004 |
Analysis of N-ras mutations in human cutaneous melanoma: tumor heterogeneity detected by polymerase chain reaction/single-stranded conformation polymorphism analysis A Van Elsas, S Zerp, S Van Der Flier, M Krüse-Wolters, A Vacca, ... Skin Cancer: Basic Science, Clinical Research and Treatment, 57-67, 1995 | 55 | 1995 |
Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin RJ Veldman, GA Koning, A van Hell, S Zerp, SR Vink, G Storm, M Verheij, ... Journal of Pharmacology and Experimental Therapeutics 315 (2), 704-710, 2005 | 38 | 2005 |
NAD+ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study SF Zerp, C Vens, B Floot, M Verheij, B van Triest Radiotherapy and Oncology 110 (2), 348-354, 2014 | 35 | 2014 |
Alkylphospholipids inhibit capillary-like endothelial tube formation in vitro: antiangiogenic properties of a new class of antitumor agents SF Zerp, SR Vink, GA Ruiter, P Koolwijk, E Peters, AH van der Luit, ... Anti-cancer drugs 19 (1), 65-75, 2008 | 30 | 2008 |
Submicromolar doses of alkyl‐lysophospholipids induce rapid internalization, but not activation, of epidermal growth factor receptor and concomitant MAPK/ERK activation in A431 … GA Ruiter, M Verheij, SF Zerp, WH Moolenaar, WJ Van Blitterswijk International journal of cancer 102 (4), 343-350, 2002 | 24 | 2002 |
Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells MC Alderliesten, JB Klarenbeek, AH van Der Luit, M Van Lummel, ... Biochemical Journal 440 (1), 127-135, 2011 | 16 | 2011 |
UV-induced N-ras mutations are T-cell targets in human melanoma A van Elsas, C Scheibenbogen, C van der Minne, SF Zerp, U Keilholz, ... Melanoma Research 7, S107-S113, 1997 | 13 | 1997 |