Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer BE Bejnordi, M Veta, PJ Van Diest, B Van Ginneken, N Karssemeijer, ... Jama 318 (22), 2199-2210, 2017 | 3010 | 2017 |
The PI3K/AKT/mTOR interactive pathway T Ersahin, N Tuncbag, R Cetin-Atalay Molecular BioSystems 11 (7), 1946-1954, 2015 | 532 | 2015 |
Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases AS Rifaioglu, H Atas, MJ Martin, R Cetin-Atalay, V Atalay, T Doğan Briefings in bioinformatics 20 (5), 1878-1912, 2019 | 434 | 2019 |
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens N Zhou, Y Jiang, TR Bergquist, AJ Lee, BZ Kacsoh, AW Crocker, ... Genome biology 20, 1-23, 2019 | 364 | 2019 |
Patika: an integrated visual environment for collaborative construction and analysis of cellular pathways E Demir, O Babur, U Dogrusoz, A Gursoy, G Nisanci, R Cetin-Atalay, ... Bioinformatics 18 (7), 996-1003, 2002 | 215 | 2002 |
DEEPScreen: high performance drug–target interaction prediction with convolutional neural networks using 2-D structural compound representations AS Rifaioglu, E Nalbat, V Atalay, MJ Martin, R Cetin-Atalay, T Doğan Chemical science 11 (9), 2531-2557, 2020 | 177 | 2020 |
ECPred: a tool for the prediction of the enzymatic functions of protein sequences based on the EC nomenclature A Dalkiran, AS Rifaioglu, MJ Martin, R Cetin-Atalay, V Atalay, T Doğan BMC bioinformatics 19, 1-13, 2018 | 145 | 2018 |
DEEPred: automated protein function prediction with multi-task feed-forward deep neural networks A Sureyya Rifaioglu, T Doğan, M Jesus Martin, R Cetin-Atalay, V Atalay Scientific reports 9 (1), 7344, 2019 | 135 | 2019 |
Near‐IR absorbing BODIPY derivatives as glutathione‐activated photosensitizers for selective photodynamic action IS Turan, FP Cakmak, DC Yildirim, R Cetin‐Atalay, EU Akkaya Chemistry–A European Journal 20 (49), 16088-16092, 2014 | 117 | 2014 |
Diet affects gut microbiota and modulates hospitalization risk differentially in an international cirrhosis cohort JS Bajaj, R Idilman, L Mabudian, M Hood, A Fagan, D Turan, MB White, ... Hepatology 68 (1), 234-247, 2018 | 113 | 2018 |
Synthesis of novel diflunisal hydrazide–hydrazones as anti-hepatitis C virus agents and hepatocellular carcinoma inhibitors S Şenkardeş, N Kaushik-Basu, I Durmaz, D Manvar, A Basu, R Atalay, ... European journal of medicinal chemistry 108, 301-308, 2016 | 107 | 2016 |
MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery AS Rifaioglu, R Cetin Atalay, D Cansen Kahraman, T Doğan, M Martin, ... Bioinformatics 37 (5), 693-704, 2021 | 86 | 2021 |
Targeting PI3K/Akt/mTOR pathway identifies differential expression and functional role of IL8 in liver cancer stem cell enrichment DC Kahraman, T Kahraman, R Cetin-Atalay Molecular cancer therapeutics 18 (11), 2146-2157, 2019 | 84 | 2019 |
Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells N Ozturk, E Erdal, M Mumcuoglu, KC Akcali, O Yalcin, S Senturk, ... Proceedings of the National Academy of Sciences 103 (7), 2178-2183, 2006 | 83 | 2006 |
Attributed relational graphs for cell nucleus segmentation in fluorescence microscopy images S Arslan, T Ersahin, R Cetin-Atalay, C Gunduz-Demir IEEE transactions on medical imaging 32 (6), 1121-1131, 2013 | 82 | 2013 |
An ontology for collaborative construction and analysis of cellular pathways E Demir, O Babur, U Dogrusoz, A Gursoy, A Ayaz, G Gulesir, G Nisanci, ... Bioinformatics 20 (3), 349-356, 2004 | 82 | 2004 |
Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: a selective survival mechanism? MB Irmak, G Ince, M Ozturk, R Cetin-Atalay Cancer Research 63 (20), 6707-6715, 2003 | 79 | 2003 |
The AKT inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated AKT-1 and synergizes with conventional chemotherapy C Simioni, AM Martelli, A Cani, R Cetin-Atalay, JA McCubrey, S Capitani, ... Oncotarget 4 (9), 1496, 2013 | 73 | 2013 |
Design, synthesis, and biological evaluation of indole-based 1, 4-disubstituted piperazines as cytotoxic agents MK Akkoç, MY Yüksel, I Durmaz, RÇ ATALAY Turkish Journal of Chemistry 36 (4), 515-525, 2012 | 72 | 2012 |
Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl) pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell … ŞC Pirol, B Çalışkan, İ Durmaz, R Atalay, E Banoglu European Journal of Medicinal Chemistry 87, 140-149, 2014 | 70 | 2014 |