Initial sequencing and analysis of the human genome US DOE Joint Genome Institute: Hawkins Trevor 4 Branscomb Elbert 4 Predki ... Nature 409 (6822), 860-921, 2001 | 24716 | 2001 |
Extensive genomic duplication during early chordate evolution A McLysaght, K Hokamp, KH Wolfe Nature genetics 31 (2), 200-204, 2002 | 642 | 2002 |
Porter: a new, accurate server for protein secondary structure prediction G Pollastri, A McLysaght Bioinformatics 21 (8), 1719-1720, 2005 | 590 | 2005 |
Recent de novo origin of human protein-coding genes DG Knowles, A McLysaght Genome research 19 (10), 1752-1759, 2009 | 333 | 2009 |
Ohnologs in the human genome are dosage balanced and frequently associated with disease T Makino, A McLysaght Proceedings of the National Academy of Sciences 107 (20), 9270, 2010 | 282 | 2010 |
Extensive gene gain associated with adaptive evolution of poxviruses A McLysaght, PF Baldi, BS Gaut Proceedings of the National Academy of Sciences 100 (26), 15655-15660, 2003 | 237 | 2003 |
Open questions in the study of de novo genes: what, how and why A McLysaght, LD Hurst Nature Reviews Genetics 17 (9), 567-578, 2016 | 211 | 2016 |
Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome E Pessia, T Makino, M Bailly-Bechet, A McLysaght, GAB Marais Proceedings of the National Academy of Sciences 109 (14), 5346-5351, 2012 | 196 | 2012 |
New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation A McLysaght, D Guerzoni Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015 | 174 | 2015 |
Dosage sensitivity is a major determinant of human copy number variant pathogenicity AM Rice, A McLysaght Nature communications 8 (1), 14366, 2017 | 148 | 2017 |
A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018 | 143 | 2018 |
A survey of host range genes in poxvirus genomes KA Bratke, A McLysaght, S Rothenburg Infection, Genetics and Evolution 14, 406-425, 2013 | 138 | 2013 |
Dosage-sensitive genes in evolution and disease AM Rice, A McLysaght BMC biology 15, 1-10, 2017 | 121 | 2017 |
Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes N Vakirlis, AR Carvunis, A McLysaght elife 9, e53500, 2020 | 114 | 2020 |
The complex relationship of gene duplication and essentiality T Makino, K Hokamp, A McLysaght Trends in genetics 25 (4), 152-155, 2009 | 111 | 2009 |
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences N Vakirlis, O Acar, B Hsu, N Castilho Coelho, SB Van Oss, A Wacholder, ... Nature communications 11 (1), 781, 2020 | 101 | 2020 |
The 2R hypothesis and the human genome sequence K Hokamp, A McLysaght, KH Wolfe Genome Evolution: Gene and Genome Duplications and the Origin of Novel Gene …, 2003 | 101 | 2003 |
Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution Y Nakatani, P Shingate, V Ravi, NE Pillai, A Prasad, A McLysaght, ... Nature communications 12 (1), 4489, 2021 | 99 | 2021 |
Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human A McLysaght, AJ Enright, L Skrabanek, KH Wolfe Yeast 17 (1), 22-36, 2000 | 98 | 2000 |
Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding AK Redmond, A McLysaght Nature communications 12 (1), 1783, 2021 | 97 | 2021 |