The nuclear envelope proteome differs notably between tissues N Korfali, GS Wilkie, SK Swanson, V Srsen, J de Las Heras, DG Batrakou, ... Nucleus 3 (6), 552-564, 2012 | 205 | 2012 |
Tissue-specific gene repositioning by muscle nuclear membrane proteins enhances repression of critical developmental genes during myogenesis MI Robson, JI de Las Heras, R Czapiewski, P Lê Thành, DG Booth, ... Molecular cell 62 (6), 834-847, 2016 | 179 | 2016 |
Formation of facultative heterochromatin in the absence of HP1 N Gilbert, S Boyle, H Sutherland, J de Las Heras, J Allan, T Jenuwein, ... The EMBO journal 22 (20), 5540-5550, 2003 | 151 | 2003 |
LSH and G9a/GLP complex are required for developmentally programmed DNA methylation K Myant, A Termanis, AYM Sundaram, T Boe, C Li, C Merusi, J Burrage, ... Genome research 21 (1), 83-94, 2011 | 141 | 2011 |
Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery N Zuleger, S Boyle, DA Kelly, JI de Las Heras, V Lazou, N Korfali, ... Genome biology 14 (2), 1-20, 2013 | 140 | 2013 |
Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations GS Wilkie, N Korfali, SK Swanson, P Malik, V Srsen, DG Batrakou, ... Molecular & Cellular Proteomics 10 (1), 2011 | 140 | 2011 |
The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture N Korfali, GS Wilkie, SK Swanson, V Srsen, DG Batrakou, EAL Fairley, ... Molecular & Cellular Proteomics 9 (12), 2571-2585, 2010 | 128 | 2010 |
Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA T Clouaire, JI de Las Heras, C Merusi, I Stancheva Nucleic acids research 38 (14), 4620-4634, 2010 | 109 | 2010 |
Cancer biology and the nuclear envelope: a convoluted relationship JI de Las Heras, DG Batrakou, EC Schirmer Seminars in cancer biology 23 (2), 125-137, 2013 | 101 | 2013 |
Tissue specificity in the nuclear envelope supports its functional complexity JI de Las Heras, P Meinke, DG Batrakou, V Srsen, N Zuleger, ARW Kerr, ... Nucleus 4 (6), 460-477, 2013 | 98 | 2013 |
Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments MI Robson, JI de Las Heras, R Czapiewski, A Sivakumar, ARW Kerr, ... Genome research 27 (7), 1126-1138, 2017 | 96 | 2017 |
Efficient metaphase II transgenesis with different transgene archetypes ACF Perry, A Rothman, JI de las Heras, P Feinstein, P Mombaerts, ... Nature biotechnology 19 (11), 1071-1073, 2001 | 83 | 2001 |
TMEM120A and B: nuclear envelope transmembrane proteins important for adipocyte differentiation DG Batrakou, JI de Las Heras, R Czapiewski, R Mouras, EC Schirmer PLoS One 10 (5), e0127712, 2015 | 70 | 2015 |
Repo-Man/PP1 regulates heterochromatin formation in interphase IJ De Castro, J Budzak, ML Di Giacinto, L Ligammari, E Gokhan, ... Nature communications 8 (1), 14048, 2017 | 60 | 2017 |
The nuclear envelope and cancer: a diagnostic perspective and historical overview JI de Las Heras, EC Schirmer Cancer Biology and the Nuclear Envelope: Recent Advances May Elucidate Past …, 2014 | 52 | 2014 |
Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression K Gordon, T Clouaire, XX Bao, SE Kemp, M Xenophontos, ... Nucleic acids research 42 (6), 3529-3541, 2014 | 46 | 2014 |
Tissue-specific NETs alter genome organization and regulation even in a heterologous system JI de Las Heras, N Zuleger, DG Batrakou, R Czapiewski, ARW Kerr, ... Nucleus 8 (1), 81-97, 2017 | 36 | 2017 |
Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy R Czapiewski, DG Batrakou, JI de Las Heras, RN Carter, A Sivakumar, ... Nature communications 13 (1), 321, 2022 | 34 | 2022 |
Spatial genome organization: from development to disease A Sivakumar, JI de Las Heras, EC Schirmer Frontiers in Cell and Developmental Biology 7, 18, 2019 | 34 | 2019 |
A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism P Meinke, ARW Kerr, R Czapiewski, JI de Las Heras, CR Dixon, E Harris, ... EBioMedicine 51, 2020 | 31 | 2020 |