| Adhesin competence repressor (AdcR) from Streptococcus pyogenes controls adaptive responses to zinc limitation and contributes to virulence M Sanson, N Makthal, AR Flores, RJ Olsen, JM Musser, M Kumaraswami Nucleic acids research 43 (1), 418-432, 2015 | 65 | 2015 |
| Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway H Do, N Makthal, AR VanderWal, MO Saavedra, RJ Olsen, JM Musser, ... Nature Communications 10 (1), 2586, 2019 | 60 | 2019 |
| Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen H Do, N Makthal, AR VanderWal, M Rettel, MM Savitski, N Peschek, ... Proceedings of the National Academy of Sciences 114 (40), E8498-E8507, 2017 | 57 | 2017 |
| Crystal structure of peroxide stress regulator from Streptococcus pyogenes provides functional insights into the mechanism of oxidative stress sensing N Makthal, S Rastegari, M Sanson, Z Ma, RJ Olsen, JD Helmann, ... Journal of Biological Chemistry 288 (25), 18311-18324, 2013 | 54 | 2013 |
| A critical role of zinc importer AdcABC in group A streptococcus-host interactions during infection and its implications for vaccine development N Makthal, K Nguyen, H Do, M Gavagan, P Chandrangsu, JD Helmann, ... EBioMedicine 21, 131-141, 2017 | 43 | 2017 |
| Iron efflux by PmtA is critical for oxidative stress resistance and contributes significantly to group A Streptococcus virulence AR VanderWal, N Makthal, A Pinochet-Barros, JD Helmann, RJ Olsen, ... Infection and immunity 85 (6), 10.1128/iai. 00091-17, 2017 | 43 | 2017 |
| An amino‐terminal signal peptide of Vfr protein negatively influences RopB‐dependent SpeB expression and attenuates virulence in Streptococcus pyogenes SA Shelburne III, RJ Olsen, N Makthal, NG Brown, P Sahasrabhojane, ... Molecular microbiology 82 (6), 1481-1495, 2011 | 38 | 2011 |
| Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus N Horstmann, CN Tran, C Brumlow, S DebRoy, H Yao, ... PLoS pathogens 14 (10), e1007354, 2018 | 37 | 2018 |
| Phosphorylation events in the multiple gene regulator of group A Streptococcus significantly influence global gene expression and virulence M Sanson, N Makthal, M Gavagan, C Cantu, RJ Olsen, JM Musser, ... Infection and immunity 83 (6), 2382-2395, 2015 | 30 | 2015 |
| Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes N Makthal, M Gavagan, H Do, RJ Olsen, JM Musser, M Kumaraswami Molecular microbiology 99 (6), 1119-1133, 2016 | 28 | 2016 |
| Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence H Do, N Makthal, P Chandrangsu, RJ Olsen, JD Helmann, JM Musser, ... Nucleic acids research 47 (14), 7476-7493, 2019 | 27 | 2019 |
| A naturally occurring single amino acid replacement in multiple gene regulator of group A Streptococcus significantly increases virulence M Sanson, BE O'Neill, P Kachroo, JR Anderson, AR Flores, C Valson, ... The American journal of pathology 185 (2), 462-471, 2015 | 24 | 2015 |
| Group A Streptococcus AdcR regulon participates in bacterial defense against host-mediated zinc sequestration and contributes to virulence N Makthal, H Do, BM Wendel, RJ Olsen, JD Helmann, JM Musser, ... Infection and Immunity 88 (8), 10.1128/iai. 00097-20, 2020 | 21 | 2020 |
| Zinc’ing it out: zinc homeostasis mechanisms and their impact on the pathogenesis of human pathogen group A streptococcus N Makthal, M Kumaraswami Metallomics 9 (12), 1693-1702, 2017 | 20 | 2017 |
| The FasX small regulatory RNA negatively regulates the expression of two fibronectin-binding proteins in group A Streptococcus JL Danger, N Makthal, M Kumaraswami, P Sumby Journal of bacteriology 197 (23), 3720-3730, 2015 | 19 | 2015 |
| Signaling by a Conserved Quorum Sensing Pathway Contributes to Growth Ex Vivo and Oropharyngeal Colonization of Human Pathogen Group A Streptococcus N Makthal, H Do, AR VanderWal, RJ Olsen, JM Musser, M Kumaraswami Infection and Immunity 86 (5), 10.1128/iai. 00169-18, 2018 | 16 | 2018 |
| Multimerization of the virulence-enhancing group A Streptococcus transcription factor RivR is required for regulatory activity A Ramalinga, JL Danger, N Makthal, M Kumaraswami, P Sumby Journal of bacteriology 199 (1), 10.1128/jb. 00452-16, 2017 | 9 | 2017 |
| Zinc’ing it out: zinc homeostasis mechanisms and their impact on the pathogenesis of human pathogen group A Streptococcus. Metallomics 9: 1693–1702 N Makthal, M Kumaraswami | 8 | 2017 |
| The leaderless communication peptide (LCP) class of quorum-sensing peptides is broadly distributed among Firmicutes S Aggarwal, E Huang, H Do, N Makthal, Y Li, E Bapteste, P Lopez, ... Nature Communications 14 (1), 5947, 2023 | 5 | 2023 |
| Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice H Do, ZR Li, PK Tripathi, S Mitra, S Guerra, A Dash, D Weerasekera, ... Nature Microbiology 9 (2), 502-513, 2024 | 3 | 2024 |
Randall OlsenHouston Methodist在 houstonmethodist.org 的电子邮件经过验证
