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Samuel Klempner, MD
Samuel Klempner, MD
Massachusetts General Hospital, Harvard Medical School
在 partners.org 的电子邮件经过验证
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引用次数
引用次数
年份
Gastric cancer, version 2.2022, NCCN clinical practice guidelines in oncology
JA Ajani, TA D’Amico, DJ Bentrem, J Chao, D Cooke, C Corvera, P Das, ...
Journal of the National Comprehensive Cancer Network 20 (2), 167-192, 2022
8562022
Tumor mutational burden is predictive of response to immune checkpoint inhibitors in MSI-high metastatic colorectal cancer
AB Schrock, C Ouyang, J Sandhu, E Sokol, D Jin, JS Ross, VA Miller, ...
Annals of Oncology 30 (7), 1096-1103, 2019
5812019
Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS–MAPK …
N Tanaka, JJ Lin, C Li, MB Ryan, J Zhang, LA Kiedrowski, AG Michel, ...
Cancer discovery 11 (8), 1913-1922, 2021
3182021
Tumor mutational burden as a predictive biomarker for response to immune checkpoint inhibitors: a review of current evidence
SJ Klempner, D Fabrizio, S Bane, M Reinhart, T Peoples, SM Ali, ...
The oncologist 25 (1), e147-e159, 2020
2942020
Real-time targeted genome profile analysis of pancreatic ductal adenocarcinomas identifies genetic alterations that might be targeted with existing drugs or used as biomarkers
AD Singhi, B George, JR Greenbowe, J Chung, J Suh, A Maitra, ...
Gastroenterology 156 (8), 2242-2253. e4, 2019
2802019
Minimal residual disease detection using a plasma-only circulating tumor DNA assay in patients with colorectal cancer
AR Parikh, EE Van Seventer, G Siravegna, AV Hartwig, A Jaimovich, Y He, ...
Clinical Cancer Research 27 (20), 5586-5594, 2021
2402021
Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition
DA Fabrizio, TJ George Jr, RF Dunne, G Frampton, J Sun, K Gowen, ...
Journal of gastrointestinal oncology 9 (4), 610, 2018
2372018
Targeted therapy in cancer
AM Tsimberidou
Cancer chemotherapy and pharmacology 76, 1113-1132, 2015
2362015
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C
R Yaeger, J Weiss, MS Pelster, AI Spira, M Barve, SHI Ou, TA Leal, ...
New England Journal of Medicine 388 (1), 44-54, 2023
1992023
Next-generation sequencing reveals a Novel NSCLC ALK F1174V mutation and confirms ALK G1202R mutation confers high-level resistance to alectinib (CH5424802/RO5424802) in ALK …
SHI Ou, M Azada, DJ Hsiang, JM Herman, TS Kain, C Siwak-Tapp, ...
Journal of Thoracic Oncology 9 (4), 549-553, 2014
1992014
What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway
SJ Klempner, AP Myers, LC Cantley
Cancer discovery 3 (12), 1345-1354, 2013
1612013
Determinants of response and intrinsic resistance to PD-1 blockade in microsatellite instability–high gastric cancer
M Kwon, M An, SJ Klempner, H Lee, KM Kim, JK Sa, HJ Cho, JY Hong, ...
Cancer discovery 11 (9), 2168-2185, 2021
1472021
Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In …
SM Ali, T Hensing, AB Schrock, J Allen, E Sanford, K Gowen, A Kulkarni, ...
The oncologist 21 (6), 762-770, 2016
1432016
Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma
C Ang, SJ Klempner, SM Ali, R Madison, JS Ross, EA Severson, ...
Oncotarget 10 (40), 4018, 2019
1322019
Receptor tyrosine kinase fusions and BRAF kinase fusions are rare but actionable resistance mechanisms to EGFR tyrosine kinase inhibitors
AB Schrock, VW Zhu, WS Hsieh, R Madison, B Creelan, J Silberberg, ...
Journal of Thoracic Oncology 13 (9), 1312-1323, 2018
1312018
Emergence of preexisting MET Y1230C mutation as a resistance mechanism to crizotinib in NSCLC with MET exon 14 skipping
SHI Ou, L Young, AB Schrock, A Johnson, SJ Klempner, VW Zhu, ...
Journal of Thoracic Oncology 12 (1), 137-140, 2017
1282017
Esophageal and esophagogastric junction cancers, version 2.2023, NCCN clinical practice guidelines in oncology
JA Ajani, TA D’Amico, DJ Bentrem, D Cooke, C Corvera, P Das, ...
Journal of the National Comprehensive Cancer Network 21 (4), 393-422, 2023
1242023
Identification and characterization of RET fusions in advanced colorectal cancer
AF Le Rolle, SJ Klempner, CR Garrett, T Seery, EM Sanford, ...
Oncotarget 6 (30), 28929, 2015
1222015
Neoadjuvant chemotherapy improves survival in patients with clinical T4b colon cancer
A Dehal, AN Graff-Baker, B Vuong, T Fischer, SJ Klempner, SC Chang, ...
Journal of Gastrointestinal Surgery 22 (2), 242-249, 2018
1142018
Comprehensive genomic profiling of advanced esophageal squamous cell carcinomas and esophageal adenocarcinomas reveals similarities and differences
K Wang, A Johnson, SM Ali, SJ Klempner, T Bekaii-Saab, JL Vacirca, ...
The oncologist 20 (10), 1132-1139, 2015
1022015
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