Cellular senescence in renal ageing and disease I Sturmlechner, M Durik, CJ Sieben, DJ Baker, JM Van Deursen Nature Reviews Nephrology 13 (2), 77-89, 2017 | 300 | 2017 |
Two-step senescence-focused cancer therapies CJ Sieben, I Sturmlechner, B van de Sluis, JM van Deursen Trends in cell biology 28 (9), 723-737, 2018 | 220 | 2018 |
p21 produces a bioactive secretome that places stressed cells under immunosurveillance I Sturmlechner, C Zhang, CC Sine, EJ van Deursen, KB Jeganathan, ... Science 374 (6567), eabb3420, 2021 | 157 | 2021 |
Osteoclasts on bone and dentin in vitro: mechanism of trail formation and comparison of resorption behavior M Rumpler, T Würger, P Roschger, E Zwettler, I Sturmlechner, P Altmann, ... Calcified tissue international 93, 526-539, 2013 | 69 | 2013 |
Anabolic and antiresorptive modulation of bone homeostasis by the epigenetic modulator sulforaphane, a naturally occurring isothiocyanate R Thaler, A Maurizi, P Roschger, I Sturmlechner, F Khani, S Spitzer, ... Journal of Biological Chemistry 291 (13), 6754-6771, 2016 | 66 | 2016 |
Ccne1 overexpression causes chromosome instability in liver cells and liver tumor development in mice K Aziz, JF Limzerwala, I Sturmlechner, E Hurley, C Zhang, KB Jeganathan, ... Gastroenterology 157 (1), 210-226. e12, 2019 | 61 | 2019 |
Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis BG Childs, C Zhang, F Shuja, I Sturmlechner, S Trewartha, RF Velasco, ... Nature aging 1 (8), 698-714, 2021 | 39 | 2021 |
Acute-phase protein serum amyloid A3 is a novel paracrine coupling factor that controls bone homeostasis R Thaler, I Sturmlechner, S Spitzer, SM Riester, M Rumpler, J Zwerina, ... The FASEB Journal 29 (4), 1344, 2015 | 35 | 2015 |
Senescent alveolar macrophages promote early-stage lung tumorigenesis LI Prieto, I Sturmlechner, SI Graves, C Zhang, NP Goplen, SY Eunhee, ... Cancer Cell 41 (7), 1261-1275. e6, 2023 | 33 | 2023 |
Vitamin C epigenetically controls osteogenesis and bone mineralization R Thaler, F Khani, I Sturmlechner, SS Dehghani, JM Denbeigh, X Zhou, ... Nature communications 13 (1), 5883, 2022 | 33 | 2022 |
p21 induces a senescence program and skeletal muscle dysfunction DA Englund, A Jolliffe, Z Aversa, X Zhang, I Sturmlechner, AE Sakamoto, ... Molecular Metabolism 67, 101652, 2023 | 28 | 2023 |
Senescent cells limit p53 activity via multiple mechanisms to remain viable I Sturmlechner, CC Sine, KB Jeganathan, C Zhang, RO Fierro Velasco, ... Nature communications 13 (1), 3722, 2022 | 21 | 2022 |
Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and … C Cherry, JI Andorko, K Krishnan, JC Mejías, HH Nguyen, KB Stivers, ... GeroScience 45 (4), 2559-2587, 2023 | 17 | 2023 |
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome CJ Sieben, KB Jeganathan, GG Nelson, I Sturmlechner, C Zhang, ... The Journal of clinical investigation 130 (1), 171-188, 2020 | 17 | 2020 |
CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging J Jin, Y Mu, H Zhang, I Sturmlechner, C Wang, RR Jadhav, Q Xia, ... Nature aging 3 (5), 600-616, 2023 | 10 | 2023 |
Senescent cells in the development of cardiometabolic disease AC Postmus, I Sturmlechner, JW Jonker, JM Van Deursen, B Van De Sluis, ... Current opinion in lipidology 30 (3), 177-185, 2019 | 10 | 2019 |
T cell fate decisions during memory cell generation with aging I Sturmlechner, A Jain, Y Mu, CM Weyand, JJ Goronzy Seminars in immunology 69, 101800, 2023 | 9 | 2023 |
FoxM1 insufficiency hyperactivates Ect2–RhoA–mDia1 signaling to drive cancer JF Limzerwala, KB Jeganathan, JA Kloeber, BA Davies, C Zhang, ... Nature cancer 1 (10), 1010-1024, 2020 | 9 | 2020 |
Stem-like CD4+ T cells in perivascular tertiary lymphoid structures sustain autoimmune vasculitis Y Sato, A Jain, S Ohtsuki, H Okuyama, I Sturmlechner, Y Takashima, ... Science translational medicine 15 (712), eadh0380, 2023 | 8 | 2023 |
TRIB2 safeguards naive T cell homeostasis during aging W Cao, I Sturmlechner, H Zhang, J Jin, B Hu, RR Jadhav, F Fang, ... Cell reports 42 (3), 2023 | 5 | 2023 |