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Yale S. Michaels
Yale S. Michaels
Scientist, Assistant Prof, CancerCare Manitoba Research Institute, University of Manitoba
在 umanitoba.ca 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Emerging approaches for regulation and control of CAR T cells: a mini review
LJB Brandt, MB Barnkob, YS Michaels, J Heiselberg, T Barington
Frontiers in Immunology 11, 326, 2020
952020
Precise tuning of gene expression levels in mammalian cells
YS Michaels, MB Barnkob, H Barbosa, TA Baeumler, MK Thompson, ...
Nature communications 10 (1), 818, 2019
692019
Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression
DJHF Knapp, YS Michaels, M Jamilly, QRV Ferry, H Barbosa, TA Milne, ...
Nature communications 10 (1), 1490, 2019
462019
DLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells
YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, ...
Science Advances 8 (34), eabn5522, 2022
312022
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency
IA Rota, AE Handel, S Maio, F Klein, F Dhalla, ME Deadman, S Cheuk, ...
Science Advances 7 (49), eabj9247, 2021
192021
Multi-objective optimization reveals time-and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development
JM Edgar, YS Michaels, PW Zandstra
NPJ Regenerative Medicine 7 (1), 11, 2022
162022
In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering
Q Wu, QRV Ferry, TA Baeumler, YS Michaels, DM Vitsios, O Habib, ...
Nature Communications 8 (1), 2109, 2017
142017
Interrogation of functional miRNA–target interactions by CRISPR/Cas9 genome engineering
YS Michaels, Q Wu, TA Fulga
MicroRNA Detection and Target Identification: Methods and Protocols, 79-97, 2017
102017
Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells
L Prochazka, YS Michaels, C Lau, RD Jones, M Siu, T Yin, D Wu, E Jang, ...
Molecular Systems Biology 18 (11), e10886, 2022
82022
Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying
N Prywes, YS Michaels, A Pal, SS Oh, JW Szostak
Chemical Communications 52 (39), 6529-6532, 2016
72016
Bioengineering translational models of lymphoid tissues
YS Michaels, CF Buchanan, N Gjorevski, A Moisan
Nature Reviews Bioengineering 1 (10), 731-748, 2023
62023
Engineering T cell development for the next generation of stem cell-derived immunotherapies
YS Michaels, LJ Durland, PW Zandstra
GEN biotechnology 2 (2), 106-119, 2023
62023
Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells
MB Barnkob, YS Michaels, V André, PS Macklin, U Gileadi, S Valvo, ...
BioRxiv, 849083, 2019
22019
Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells
MB Barnkob, YS Michaels, V André, PS Macklin, U Gileadi, S Valvo, ...
nature communications 15 (1), 3173, 2024
12024
Time-and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification
YS Michaels, MC Major, B Bonham-Carter, J Zhang, T Heydari, JM Edgar, ...
bioRxiv, 2023.10. 06.561277, 2023
12023
Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering
Q Wu, YS Michaels, TA Fulga
MicroRNA Detection and Target Identification: Methods and Protocols, 243-264, 2023
12023
Discrete-to-analog signal conversion in human pluripotent stem cells
L Prochazka, YS Michaels, C Lau, M Siu, T Yin, D Wu, E Jang, RD Jones, ...
bioRxiv, 2021.11. 05.467377, 2021
12021
Precise tuning of gene expression output levels in mammalian cells
YS Michaels, MB Barnkob, H Barbosa, TA Baeumler, MK Thompson, ...
bioRxiv, 352377, 2018
12018
3164–IDENTIFICATION OF GENE REGULATORY NETWORKS ESSENTIAL FOR HEMATOPOIETIC PROGENITOR CELL AND T CELL EMERGENCE FROM HUMAN PLURIPOTENT STEM CELL VIA CRISPR SCREENS
M Siu, E Flaschner, Y Michaels, P Zandstra
Experimental Hematology 137, 104484, 2024
2024
A method for producing blood progenitor and progenitor t cells, resulting cells and methods and uses thereof
PW Zandstra, YS Michaels
US Patent App. 18/561,873, 2024
2024
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