Reduced sensory synaptic excitation impairs motor neuron function via Kv2. 1 in spinal muscular atrophy EV Fletcher, CM Simon, JG Pagiazitis, JI Chalif, A Vukojicic, E Drobac, ... Nature neuroscience 20 (7), 905-916, 2017 | 119 | 2017 |
The classical complement pathway mediates microglia-dependent remodeling of spinal motor circuits during development and in SMA A Vukojicic, N Delestrée, EV Fletcher, JG Pagiazitis, S Sankaranarayanan, ... Cell reports 29 (10), 3087-3100. e7, 2019 | 105 | 2019 |
Converging mechanisms of p53 activation drive motor neuron degeneration in spinal muscular atrophy CM Simon, Y Dai, M Van Alstyne, C Koutsioumpa, JG Pagiazitis, JI Chalif, ... Cell reports 21 (13), 3767-3780, 2017 | 96 | 2017 |
Sensory-derived glutamate regulates presynaptic inhibitory terminals in mouse spinal cord M Mende, EV Fletcher, JL Belluardo, JP Pierce, PK Bommareddy, ... Neuron 90 (6), 1189-1202, 2016 | 46 | 2016 |
Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents A Roux, L Muller, SN Jackson, K Baldwin, V Womack, JG Pagiazitis, ... ACS chemical neuroscience 6 (2), 247-259, 2015 | 37 | 2015 |
Control of mammalian locomotion by ventral spinocerebellar tract neurons JI Chalif, M de Lourdes Martínez-Silva, JG Pagiazitis, AJ Murray, ... Cell 185 (2), 328-344. e26, 2022 | 34 | 2022 |
Chronic pharmacological increase of neuronal activity improves sensory-motor dysfunction in spinal muscular atrophy mice CM Simon, B Blanco-Redondo, JM Buettner, JG Pagiazitis, EV Fletcher, ... Journal of Neuroscience 41 (2), 376-389, 2021 | 19 | 2021 |
Converging mechanisms of p53 activation drive motor neuron degeneration in spinal muscular atrophy. Cell Rep 21: 3767–3780 CM Simon, Y Dai, M Van Alstyne, C Koutsioumpa, JG Pagiazitis, JI Chalif, ... | 7 | 2017 |
Dysfunction of proprioceptive sensory synapses is a pathogenic event and therapeutic target in mice and humans with spinal muscular atrophy CM Simon, N Delestree, J Montes, F Gerstner, E Carranza, L Sowoidnich, ... medRxiv, 2024.06. 03.24308132, 2024 | | 2024 |
Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy N Delestrée, E Semizoglou, JG Pagiazitis, A Vukojicic, E Drobac, ... Brain 146 (11), 4574-4593, 2023 | | 2023 |
Increase of neuronal activity by 4-Aminopyridine improves sensory-motor dysfunction in a mouse model of SMA JK Longang, J Pagiazitis, E Fletcher, BB Redondo, J Buettner, G Mentis, ... ACTA PHYSIOLOGICA 227, 2019 | | 2019 |