Intrinsic antibiotic resistance: mechanisms, origins, challenges and solutions G Cox, GD Wright International Journal of Medical Microbiology 303 (6-7), 287-292, 2013 | 870 | 2013 |
A common platform for antibiotic dereplication and adjuvant discovery G Cox, A Sieron, AM King, G De Pascale, AC Pawlowski, K Koteva, ... Cell chemical biology 24 (1), 98-109, 2017 | 133 | 2017 |
Plazomicin retains antibiotic activity against most aminoglycoside modifying enzymes G Cox, L Ejim, PJ Stogios, K Koteva, E Bordeleau, E Evdokimova, ... ACS infectious diseases 4 (6), 980-987, 2018 | 125 | 2018 |
The evolutionary conservation of Escherichia coli drug efflux pumps supports physiological functions T Teelucksingh, LK Thompson, G Cox Journal of bacteriology 202 (22), 10.1128/jb. 00367-20, 2020 | 67 | 2020 |
Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT (2 ″)-Ia G Cox, PJ Stogios, A Savchenko, GD Wright MBio 6 (1), 10.1128/mbio. 02180-14, 2015 | 63 | 2015 |
An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria G Cox, K Koteva, GD Wright Journal of Antimicrobial Chemotherapy 69 (7), 1844-1855, 2014 | 58 | 2014 |
Rox, a rifamycin resistance Enzyme with an unprecedented mechanism of action K Koteva, G Cox, JK Kelso, MD Surette, HL Zubyk, L Ejim, P Stogios, ... Cell chemical biology 25 (4), 403-412. e5, 2018 | 54 | 2018 |
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid G Cox, GS Thompson, HT Jenkins, F Peske, A Savelsbergh, MV Rodnina, ... Proceedings of the National Academy of Sciences 109 (6), 2102-2107, 2012 | 53 | 2012 |
Inhibition of the ANT (2 ″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones DR Hirsch, G Cox, MP D’Erasmo, T Shakya, C Meck, N Mohd, GD Wright, ... Bioorganic & medicinal chemistry letters 24 (21), 4943-4947, 2014 | 52 | 2014 |
Rifampin phosphotransferase is an unusual antibiotic resistance kinase PJ Stogios, G Cox, P Spanogiannopoulos, MC Pillon, N Waglechner, ... Nature communications 7, 11343, 2016 | 49 | 2016 |
Bacterial Anti-adhesives: Inhibition of Staphylococcus aureus Nasal Colonization AC Leonard, LE Petrie, G Cox ACS Infectious Diseases 5 (10), 1668-1681, 2019 | 29 | 2019 |
“tet(U)” Is Not a Tetracycline Resistance Determinant JA Caryl, G Cox, S Trimble, AJ O'Neill Antimicrobial agents and chemotherapy 56 (6), 3378-3379, 2012 | 23 | 2012 |
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis PJ Stogios, G Cox, HL Zubyk, E Evdokimova, Z Wawrzak, GD Wright, ... ACS chemical biology 13 (5), 1322-1332, 2018 | 19 | 2018 |
A genetic platform to investigate the functions of bacterial drug efflux pumps T Teelucksingh, LK Thompson, S Zhu, NM Kuehfuss, JA Goetz, SE Gilbert, ... Nature Chemical Biology 18 (12), 1399-1409, 2022 | 17 | 2022 |
Staphylococcus aureus adhesion to the host KA Berry, MTA Verhoef, AC Leonard, G Cox Annals of the New York Academy of Sciences 1515 (1), 75-96, 2022 | 17 | 2022 |
Old problems and new solutions: antibiotic alternatives in food animal production C Stoica, G Cox Canadian journal of microbiology 67 (6), 427-444, 2021 | 17 | 2021 |
Resistance-guided discovery of elfamycin antibiotic producers with antigonococcal activity V Yarlagadda, R Medina, TA Johnson, KP Koteva, G Cox, MN Thaker, ... ACS Infectious Diseases 6 (12), 3163-3173, 2020 | 16 | 2020 |
Development and validation of a high-throughput whole cell assay to investigate Staphylococcus aureus adhesion to host ligands LE Petrie, AC Leonard, J Murphy, G Cox Journal of Biological Chemistry 295 (49), 16700-16712, 2020 | 12 | 2020 |
Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins AC Leonard, MI Goncheva, SE Gilbert, H Shareefdeen, LE Petrie, ... Proceedings of the National Academy of Sciences 120 (12), e2301414120, 2023 | 9 | 2023 |
Mutagenesis mapping of the protein-protein interaction underlying FusB-type fusidic acid resistance G Cox, TA Edwards, AJ O'Neill Antimicrobial agents and chemotherapy 57 (10), 4640-4644, 2013 | 7 | 2013 |