| ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ... Nature neuroscience 22 (2), 167-179, 2019 | 490 | 2019 |
| A defined glycosaminoglycan-binding substratum for human pluripotent stem cells JR Klim, L Li, PJ Wrighton, MS Piekarczyk, LL Kiessling Nature methods 7 (12), 989-994, 2010 | 340 | 2010 |
| Modeling ALS with motor neurons derived from human induced pluripotent stem cells S Sances, LI Bruijn, S Chandran, K Eggan, R Ho, JR Klim, MR Livesey, ... Nature neuroscience 19 (4), 542-553, 2016 | 326 | 2016 |
| Genetic ablation of AXL does not protect human neural progenitor cells and cerebral organoids from Zika virus infection MF Wells, MR Salick, O Wiskow, DJ Ho, KA Worringer, RJ Ihry, ... Cell stem cell 19 (6), 703-708, 2016 | 298 | 2016 |
| How to make spinal motor neurons BN Davis-Dusenbery, LA Williams, JR Klim, K Eggan Development 141 (3), 491-501, 2014 | 181 | 2014 |
| High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells R Derda, S Musah, BP Orner, JR Klim, L Li, LL Kiessling Journal of the American Chemical Society 132 (4), 1289-1295, 2010 | 166 | 2010 |
| Reactive astrocytes promote ALS-like degeneration and intracellular protein aggregation in human motor neurons by disrupting autophagy through TGF-β1 P Tripathi, N Rodriguez-Muela, JR Klim, AS de Boer, S Agrawal, ... Stem cell reports 9 (2), 667-680, 2017 | 153 | 2017 |
| Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein SMK Farhan, DP Howrigan, LE Abbott, JR Klim, SD Topp, AE Byrnes, ... Nature neuroscience 22 (12), 1966-1974, 2019 | 121 | 2019 |
| Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins PJ Wrighton, JR Klim, BA Hernandez, CH Koonce, TJ Kamp, LL Kiessling Proceedings of the National Academy of Sciences 111 (51), 18126-18131, 2014 | 74 | 2014 |
| Spatial control of cell fate using synthetic surfaces to potentiate TGF-β signaling L Li, JR Klim, R Derda, AH Courtney, LL Kiessling Proceedings of the National Academy of Sciences 108 (29), 11745-11750, 2011 | 64 | 2011 |
| Loss of mouse Stmn2 function causes motor neuropathy IG San Juan, LA Nash, KS Smith, MF Leyton-Jaimes, M Qian, JR Klim, ... Neuron 110 (10), 1671-1688. e6, 2022 | 58 | 2022 |
| Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation X Huang, KCD Roet, L Zhang, A Brault, AP Berg, AB Jefferson, ... Cell reports 35 (10), 2021 | 54 | 2021 |
| Connecting TDP-43 pathology with neuropathy JR Klim, G Pintacuda, LA Nash, IG San Juan, K Eggan Trends in neurosciences 44 (6), 424-440, 2021 | 49 | 2021 |
| Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients DA Mordes, M Prudencio, LD Goodman, JR Klim, R Moccia, F Limone, ... Acta neuropathologica communications 6, 1-13, 2018 | 33 | 2018 |
| Antisense oligonucleotide therapies for Amyotrophic Lateral Sclerosis: Existing and emerging targets JR Klim, C Vance, EL Scotter The International Journal of Biochemistry & Cell Biology 110, 149-153, 2019 | 29 | 2019 |
| Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues F Limone, IG San Juan, JM Mitchell, JLM Smith, K Raghunathan, D Meyer, ... Cell reports 42 (1), 2023 | 27 | 2023 |
| Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology M de Majo, M Koontz, E Marsan, N Salinas, A Ramsey, YM Kuo, K Seo, ... Stem cell reports 18 (3), 706-719, 2023 | 23 | 2023 |
| Small-Molecule-Modified Surfaces Engage Cells through the αvβ3 Integrin JR Klim, AJ Fowler, AH Courtney, PJ Wrighton, RTC Sheridan, ML Wong, ... ACS Chemical Biology 7 (3), 518-525, 2012 | 21 | 2012 |
| Pluripotent stem cell strategies for rebuilding the human brain F Limone, JR Klim, DA Mordes Frontiers in Aging Neuroscience 14, 1017299, 2022 | 11 | 2022 |
| Publisher Correction: Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein SMK Farhan, DP Howrigan, LE Abbott, JR Klim, SD Topp, AE Byrnes, ... Nature neuroscience 23 (2), 295-296, 2020 | 5 | 2020 |
