Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer AJ Wilson, DS Byun, N Popova, LB Murray, K L'Italien, Y Sowa, D Arango, ... Journal of Biological Chemistry 281 (19), 13548-13558, 2006 | 741 | 2006 |
PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab M Jhawer, S Goel, AJ Wilson, C Montagna, YH Ling, DS Byun, S Nasser, ... Cancer research 68 (6), 1953-1961, 2008 | 584 | 2008 |
Metastasis-associated gene expression changes predict poor outcomes in patients with Dukes stage B and C colorectal cancer RN Jorissen, P Gibbs, M Christie, S Prakash, L Lipton, J Desai, D Kerr, ... Clinical Cancer Research 15 (24), 7642-7651, 2009 | 477 | 2009 |
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer D Mouradov, C Sloggett, RN Jorissen, CG Love, S Li, AW Burgess, ... Cancer research 74 (12), 3238-3247, 2014 | 444 | 2014 |
A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition S Ropero, MF Fraga, E Ballestar, R Hamelin, H Yamamoto, ... Nature genetics 38 (5), 566-569, 2006 | 348 | 2006 |
Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells D Arango, AJ Wilson, Q Shi, GA Corner, MJ Aranes, C Nicholas, M Lesser, ... British journal of cancer 91 (11), 1931-1946, 2004 | 327 | 2004 |
Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin JM Mariadason, D Arango, Q Shi, AJ Wilson, GA Corner, C Nicholas, ... Cancer research 63 (24), 8791-8812, 2003 | 261 | 2003 |
HDAC4 promotes growth of colon cancer cells via repression of p21 AJ Wilson, DS Byun, S Nasser, LB Murray, K Ayyanar, D Arango, ... Molecular biology of the cell 19 (10), 4062-4075, 2008 | 252 | 2008 |
SMAD4 as a prognostic marker in colorectal cancer H Alazzouzi, P Alhopuro, R Salovaara, H Sammalkorpi, H Järvinen, ... Clinical Cancer Research 11 (7), 2606-2611, 2005 | 247 | 2005 |
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status C Oliveira, JL Westra, D Arango, M Ollikainen, E Domingo, A Ferreira, ... Human molecular genetics 13 (19), 2303-2311, 2004 | 238 | 2004 |
Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis JM Mariadason, C Nicholas, EL Kaitlin, M Zhuang, HJM Smartt, ... Gastroenterology 128 (4), 1081-1088, 2005 | 225 | 2005 |
Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis P Laiho, A Kokko, S Vanharanta, R Salovaara, H Sammalkorpi, ... Oncogene 26 (2), 312-320, 2007 | 189 | 2007 |
Gene-expression profiling predicts recurrence in Dukes’ C colorectal cancer D Arango, P Laiho, A Kokko, P Alhopuro, H Sammalkorpi, R Salovaara, ... Gastroenterology 129 (3), 874-884, 2005 | 157 | 2005 |
TR3/Nur77 in colon cancer cell apoptosis AJ Wilson, D Arango, JM Mariadason, BG Heerdt, LH Augenlicht Cancer research 63 (17), 5401-5407, 2003 | 157 | 2003 |
Candidate driver genes in microsatellite‐unstable colorectal cancer P Alhopuro, H Sammalkorpi, I Niittymäki, M Biström, A Raitila, J Saharinen, ... International journal of cancer 130 (7), 1558-1566, 2012 | 149 | 2012 |
c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo D Arango, GA Corner, S Wadler, PJ Catalano, LH Augenlicht Cancer research 61 (12), 4910-4915, 2001 | 149 | 2001 |
A Gene Expression Profile That Defines Colon Cell Maturation in Vitro JM Mariadason, D Arango, GA Corner, MJ Arañes, KA Hotchkiss, W Yang, ... Cancer research 62 (16), 4791-4804, 2002 | 148 | 2002 |
Na+/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: Molecular characterization of SMCT V Paroder, SR Spencer, M Paroder, D Arango, S Schwartz Jr, ... Proceedings of the National Academy of Sciences 103 (19), 7270-7275, 2006 | 134 | 2006 |
SMAD4 levels and response to 5-fluorouracil in colorectal cancer P Alhopuro, H Alazzouzi, H Sammalkorpi, V Dávalos, R Salovaara, ... Clinical cancer research 11 (17), 6311-6316, 2005 | 132 | 2005 |
Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors H Alazzouzi, V Davalos, A Kokko, E Domingo, SM Woerner, AJ Wilson, ... Cancer research 65 (22), 10170-10173, 2005 | 125 | 2005 |