Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies YC Sung, PR Jin, LA Chu, FF Hsu, MR Wang, CC Chang, SJ Chiou, ... Nature nanotechnology 14 (12), 1160-1169, 2019 | 303 | 2019 |
Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer KW Huang, FF Hsu, JT Qiu, GJ Chern, YA Lee, CC Chang, YT Huang, ... Science advances 6 (3), eaax5032, 2020 | 193 | 2020 |
CXCR4-targeted lipid-coated PLGA nanoparticles deliver sorafenib and overcome acquired drug resistance in liver cancer DY Gao, TT Lin, YC Sung, YC Liu, WH Chiang, CC Chang, JY Liu, ... Biomaterials 67, 194-203, 2015 | 131 | 2015 |
Development and characterization of sorafenib-loaded PLGA nanoparticles for the systemic treatment of liver fibrosis TT Lin, DY Gao, YC Liu, YC Sung, D Wan, JY Liu, T Chiang, L Wang, ... Journal of controlled release 221, 62-70, 2016 | 97 | 2016 |
Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development YC Sung, YC Liu, PH Chao, CC Chang, PR Jin, TT Lin, JA Lin, HT Cheng, ... Theranostics 8 (4), 894, 2018 | 85 | 2018 |
Nanoparticle Delivery of MnO2 and Antiangiogenic Therapy to Overcome Hypoxia-Driven Tumor Escape and Suppress Hepatocellular Carcinoma CC Chang, TK Dinh, YA Lee, FN Wang, YC Sung, PL Yu, SC Chiu, ... ACS Applied Materials & Interfaces 12 (40), 44407-44419, 2020 | 83 | 2020 |
Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors Y Chen, YC Liu, YC Sung, RR Ramjiawan, TT Lin, CC Chang, KS Jeng, ... Scientific reports 7 (1), 44123, 2017 | 74 | 2017 |
Galactose derivative-modified nanoparticles for efficient siRNA delivery to hepatocellular carcinoma KW Huang, YT Lai, GJ Chern, SF Huang, CL Tsai, YC Sung, CC Chiang, ... Biomacromolecules 19 (6), 2330-2339, 2018 | 70 | 2018 |
Multiresolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism AYT Wu, YC Sung, YJ Chen, STY Chou, V Guo, JCY Chien, JJS Ko, ... Advanced Science 7 (19), 2001467, 2020 | 60 | 2020 |
A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment JS Song, CC Chang, CH Wu, TK Dinh, JJ Jan, KW Huang, MC Chou, ... Proceedings of the National Academy of Sciences 118 (13), e2015433118, 2021 | 53 | 2021 |
A multifunctional nanocarrier for efficient TRAIL‐based gene therapy against hepatocellular carcinoma with desmoplasia in mice CH Liu, GJ Chern, FF Hsu, KW Huang, YC Sung, HC Huang, JT Qiu, ... Hepatology 67 (3), 899-913, 2018 | 45 | 2018 |
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles SA Dilliard, Y Sun, MO Brown, YC Sung, S Chatterjee, L Farbiak, ... Journal of Controlled Release 361, 361-372, 2023 | 25 | 2023 |
Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours HC Huang, YC Sung, CP Li, D Wan, PH Chao, YT Tseng, BW Liao, ... Gut 71 (9), 1843-1855, 2022 | 22 | 2022 |
Membrane protein modification modulates big and small extracellular vesicle biodistribution and tumorigenic potential in breast cancers in vivo BJA Magoling, AYT Wu, YJ Chen, WWT Wong, STY Chuo, HC Huang, ... Advanced Materials 35 (13), 2208966, 2023 | 19 | 2023 |
Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis HT Cheng, HC Huang, TY Lee, YH Liao, YH Sheng, PR Jin, KW Huang, ... Journal of Controlled Release 346, 169-179, 2022 | 16 | 2022 |
An in vitro fibrotic liver lobule model through sequential cell-seeding of HSCs and HepG2 on 3D-printed poly (glycerol sebacate) acrylate scaffolds SK Hsiao, CW Liang, TL Chang, YC Sung, YT Chen, Y Chen, J Wang Journal of Materials Chemistry B 10 (46), 9590-9598, 2022 | 2 | 2022 |
In vivo editing of lung stem cells for durable gene correction in mice Y Sun, S Chatterjee, X Lian, Z Traylor, SR Sattiraju, Y Xiao, SA Dilliard, ... Science 384 (6701), 1196-1202, 2024 | 1 | 2024 |
Redirected tropisms of extracellular vesicles and exomeres yield distinct biodistribution profiles AYT Wu, YC Sung, STY Chou, V Guo, JCY Chien, JJS Ko, AL Yang, ... bioRxiv, 2020.03. 27.012625, 2020 | 1 | 2020 |
Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells X Lian, S Chatterjee, Y Sun, SA Dilliard, S Moore, Y Xiao, X Bian, ... Nature Nanotechnology, 1-9, 2024 | | 2024 |
Enhancing cancer treatment Via a nanostructured chemoimmunotherapy gel facilitating interleukin-2 delivery and immunogenic cell death induction H Yu Mu, YNN Ta, JRM Tham, FF Hsu, YC Lin, HC Huang, YC Sung, ... Cancer Research 84 (6_Supplement), 5737-5737, 2024 | | 2024 |