PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery M Ogris, S Brunner, S Schüller, R Kircheis, E Wagner Gene therapy 6 (4), 595-605, 1999 | 1535 | 1999 |
Transferrin-polycation conjugates as carriers for DNA uptake into cells. E Wagner, M Zenke, M Cotten, H Beug, ML Birnstiel Proceedings of the National Academy of Sciences 87 (9), 3410-3414, 1990 | 1040 | 1990 |
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. C Plank, B Oberhauser, K Mechtler, C Koch, E Wagner Journal of Biological Chemistry 269 (17), 12918-12924, 1994 | 984 | 1994 |
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. E Wagner, C Plank, K Zatloukal, M Cotten, ML Birnstiel Proceedings of the National Academy of Sciences 89 (17), 7934-7938, 1992 | 972 | 1992 |
Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. DT Curiel, S Agarwal, E Wagner, M Cotten Proceedings of the National Academy of Sciences 88 (19), 8850-8854, 1991 | 937 | 1991 |
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo L Wightman, R Kircheis, V Rössler, S Carotta, R Ruzicka, M Kursa, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2001 | 905 | 2001 |
Design and gene delivery activity of modified polyethylenimines R Kircheis, L Wightman, E Wagner Advanced drug delivery reviews 53 (3), 341-358, 2001 | 878 | 2001 |
Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery C Plank, K Mechtler, FC Szoka Jr, E Wagner Human gene therapy 7 (12), 1437-1446, 1996 | 785 | 1996 |
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells M Ogris, P Steinlein, M Kursa, K Mechtler, R Kircheis, E Wagner Gene therapy 5 (10), 1425-1433, 1998 | 771 | 1998 |
Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells. E Wagner, M Cotten, R Foisner, ML Birnstiel Proceedings of the National Academy of Sciences 88 (10), 4255-4259, 1991 | 761 | 1991 |
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. E Wagner, K Zatloukal, M Cotten, H Kirlappos, K Mechtler, DT Curiel, ... Proceedings of the national academy of sciences 89 (13), 6099-6103, 1992 | 755 | 1992 |
Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus S Brunner, T Sauer, S Carotta, M Cotten, M Saltik, E Wagner Gene therapy 7 (5), 401-407, 2000 | 700 | 2000 |
Polylysine-based transfection systems utilizing receptor-mediated delivery W Zauner, M Ogris, E Wagner Advanced drug delivery reviews 30 (1-3), 97-113, 1998 | 696 | 1998 |
Nomenclature for synthetic gene delivery systems PL Felgner, Y Barenholz, JP Behr, SH Cheng, P Cullis, L Huang, ... Human gene therapy 8 (5), 511-512, 1997 | 637 | 1997 |
Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity A Zintchenko, A Philipp, A Dehshahri, E Wagner Bioconjugate chemistry 19 (7), 1448-1455, 2008 | 577 | 2008 |
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer S Boeckle, K von Gersdorff, S van der Piepen, C Culmsee, E Wagner, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 546 | 2004 |
Nucleic acid therapeutics using polyplexes: a journey of 50 years (and beyond) U Lächelt, E Wagner Chemical reviews 115 (19), 11043-11078, 2015 | 542 | 2015 |
Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin … M Cotten, F Längle-Rouault, H Kirlappos, E Wagner, K Mechtler, M Zenke, ... Proceedings of the National Academy of Sciences 87 (11), 4033-4037, 1990 | 539 | 1990 |
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery R Kircheis, A Kichler, G Wallner, M Kursa, M Ogris, T Felzmann, ... Gene therapy 4 (5), 409-418, 1997 | 524 | 1997 |
High-efficiency gene transfer mediated by adenovirus coupled to DNA–polylysine complexes DT Curiel, E Wagner, M Cotten, ML Birnstiel, S Agarwal, CM Li, S Loechel, ... Human gene therapy 3 (2), 147-154, 1992 | 518 | 1992 |