A DNA damage checkpoint response in telomere-initiated senescence FA Fagagna, PM Reaper, L Clay-Farrace, H Fiegler, P Carr, ... Nature 426 (6963), 194-198, 2003 | 3165 | 2003 |
Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? T von Zglinicki, G Saretzki, W Döcke, C Lotze Experimental cell research 220 (1), 186-193, 1995 | 1103 | 1995 |
Feedback between p21 and reactive oxygen production is necessary for cell senescence JF Passos, G Nelson, C Wang, T Richter, C Simillion, CJ Proctor, S Miwa, ... Molecular systems biology 6 (1), 347, 2010 | 997 | 2010 |
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence JF Passos, G Saretzki, S Ahmed, G Nelson, T Richter, H Peters, I Wappler, ... PLoS biology 5 (5), e110, 2007 | 783 | 2007 |
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 776 | 2014 |
Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 636 | 2016 |
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress S Ahmed, JF Passos, MJ Birket, T Beckmann, S Brings, H Peters, ... Journal of cell science 121 (7), 1046-1053, 2008 | 545 | 2008 |
Preferential accumulation of single-stranded regions in telomeres of human fibroblasts S Petersen, G Saretzki, T von Zglinicki Experimental cell research 239 (1), 152-160, 1998 | 532 | 1998 |
Human cell senescence as a DNA damage response T Von Zglinicki, G Saretzki, J Ladhoff, FA di Fagagna, SP Jackson Mechanisms of ageing and development 126 (1), 111-117, 2005 | 529 | 2005 |
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? JF Passos, G Saretzki, T Von Zglinicki Nucleic acids research 35 (22), 7505-7513, 2007 | 400 | 2007 |
Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? T Von Zglinicki, V Serra, M Lorenz, G Saretzki, R Lenzen-Groβimlighaus, ... Laboratory investigation 80 (11), 1739-1747, 2000 | 378 | 2000 |
Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells L Armstrong, K Tilgner, G Saretzki, SP Atkinson, M Stojkovic, R Moreno, ... Stem cells 28 (4), 661-673, 2010 | 338 | 2010 |
Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells G Saretzki, L Armstrong, A Leake, M Lako, T von Zglinicki Stem cells 22 (6), 962-971, 2004 | 338 | 2004 |
Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening V Serra, T Von Zglinicki, M Lorenz, G Saretzki Journal of Biological Chemistry 278 (9), 6824-6830, 2003 | 335 | 2003 |
Replicative aging, telomeres, and oxidative stress G Saretzki, T Von Zglinicki Annals of the New York Academy of Sciences 959 (1), 24-29, 2002 | 331 | 2002 |
Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells G Saretzki, T Walter, S Atkinson, JF Passos, B Bareth, WN Keith, ... Stem cells 26 (2), 455-464, 2008 | 310 | 2008 |
MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress G Saretzki, MP Murphy, T Von Zglinicki Aging cell 2 (2), 141-143, 2003 | 235 | 2003 |
Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments G Saretzki, N Sitte, U Merkel, RE Wurm, T von Zglinicki Oncogene 18 (37), 5148-5158, 1999 | 234 | 1999 |
SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis AJ Valentijn, K Palial, H Al-Lamee, N Tempest, J Drury, T Von Zglinicki, ... Human reproduction 28 (10), 2695-2708, 2013 | 208 | 2013 |
Accelerated telomere shortening in fibroblasts after extended periods of confluency N Sitte, G Saretzki, T von Zglinicki Free Radical Biology and Medicine 24 (6), 885-893, 1998 | 207 | 1998 |