CD38-driven mitochondrial trafficking promotes bioenergetic plasticity in multiple myeloma CR Marlein, RE Piddock, JJ Mistry, L Zaitseva, C Hellmich, RH Horton, ... Cancer Research 79 (9), 2285-2297, 2019 | 182 | 2019 |
ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection JJ Mistry, CR Marlein, JA Moore, C Hellmich, EE Wojtowicz, JGW Smith, ... Proceedings of the National Academy of Sciences 116 (49), 24610-24619, 2019 | 102 | 2019 |
Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment AM Abdul-Aziz, Y Sun, C Hellmich, CR Marlein, J Mistry, E Forde, ... Blood, The Journal of the American Society of Hematology 133 (5), 446-456, 2019 | 83 | 2019 |
Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection JJ Mistry, C Hellmich, JA Moore, A Jibril, I Macaulay, M Moreno-Gonzalez, ... Nature Communications 12 (1), 7130, 2021 | 61 | 2021 |
Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis JM SanMiguel, E Eudy, MA Loberg, KA Young, JJ Mistry, KD Mujica, ... Cancer discovery 12 (12), 2763-2773, 2022 | 40 | 2022 |
LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation JA Moore, JJ Mistry, C Hellmich, RH Horton, EE Wojtowicz, A Jibril, ... The Journal of clinical investigation 132 (5), 2022 | 38 | 2022 |
Daratumumab inhibits acute myeloid leukemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells JJ Mistry, JA Moore, P Kumar, CR Marlein, C Hellmich, G Pillinger, A Jibril, ... Haematologica 106 (2), 589, 2021 | 29 | 2021 |
S100P enhances the motility and invasion of human trophoblast cell lines MEA Tabrizi, TL Lancaster, TM Ismail, A Georgiadou, A Ganguly, JJ Mistry, ... Scientific Reports 8 (1), 11488, 2018 | 22 | 2018 |
PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma PR Kumar, M Saad, C Hellmich, JJ Mistry, JA Moore, S Conway, ... British journal of cancer 127 (1), 69-78, 2022 | 16 | 2022 |
Hematopoietic stem cell aging and leukemia transformation PA Colom Díaz, JJ Mistry, JJ Trowbridge Blood 142 (6), 533-542, 2023 | 15 | 2023 |
Cell origin–dependent cooperativity of mutant Dnmt3a and Npm1 in clonal hematopoiesis and myeloid malignancy JM SanMiguel, E Eudy, MA Loberg, LA Miles, T Stearns, JJ Mistry, ... Blood Advances 6 (12), 3666-3677, 2022 | 12 | 2022 |
Daratumumab inhibits AML metabolic capacity and tumor growth through inhibition of CD38 mediated mitochondrial transfer from bone marrow stromal cells to blasts in the leukemic … JJ Mistry, C Hellmich, JA Moore, CR Marlein, G Pillinger, A Collins, ... Blood 134, 1385, 2019 | 10 | 2019 |
Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia JJ Mistry, C Hellmich, A Lambert, JA Moore, A Jibril, A Collins, KM Bowles, ... Biomarker research 9 (1), 35, 2021 | 7 | 2021 |
Plasma cell–derived mtDAMPs activate the macrophage STING pathway, promoting myeloma progression A Jibril, C Hellmich, EE Wojtowicz, K Hampton, R Maynard, R De Silva, ... Blood, The Journal of the American Society of Hematology 141 (25), 3065-3077, 2023 | 5 | 2023 |
p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors C Hellmich, E Wojtowicz, JA Moore, JJ Mistry, A Jibril, BB Johnson, ... Blood Advances 7 (2), 256-268, 2023 | 5 | 2023 |
Performance and health economic evaluation of the Mount Sinai COVID-19 serological assay identifies modification of thresholding as necessary to maximise specificity of the assay SA Rushworth, BB Johnson, K Ashurst, R Davidson, P Paddy, JJ Mistry, ... medRxiv, 2020.06. 11.20128306, 2020 | 5 | 2020 |
HSC-derived fatty acid oxidation in steady-state and stressed hematopoiesis JJ Mistry, K Bowles, SA Rushworth Experimental hematology 117, 1-8, 2023 | 4 | 2023 |
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion EE Wojtowicz, JJ Mistry, V Uzun, C Hellmich, A Scoones, DW Chin, ... Genome Biology 24 (1), 152, 2023 | 2 | 2023 |
Bone Marrow Stromal Cell Senescence Induced By Dnmt3a-Mutant Hematopoietic Stem and Progenitor Cells Accelerates Clonal Hematopoiesis and Progression to Leukemia JJ Mistry, KA Young, JJ Trowbridge Blood 140 (Supplement 1), 1265-1265, 2022 | 2 | 2022 |
Enhanced Free Fatty Acid Uptake Via CD36 Promotes a Metabolic Switch to B-Oxidation within Hematopoietic Stem Cells in Response to Acute Infection JJ Mistry, JA Moore, C Hellmich, A Jibril, I Macauley, M Moreno-Gonzalez, ... Blood 136, 39-40, 2020 | 2 | 2020 |