A perspective on multi-target drug discovery and design for complex diseases RR Ramsay, MR Popovic-Nikolic, K Nikolic, E Uliassi, ML Bolognesi Clinical and translational medicine 7, 1-14, 2018 | 605 | 2018 |
Multitarget compounds bearing tacrine-and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease L Ismaili, B Refouvelet, M Benchekroun, S Brogi, M Brindisi, S Gemma, ... Progress in neurobiology 151, 4-34, 2017 | 185 | 2017 |
Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase … OM Bautista-Aguilera, G Esteban, I Bolea, K Nikolic, D Agbaba, ... European journal of medicinal chemistry 75, 82-95, 2014 | 156 | 2014 |
In silico Methods for Design of Kinase Inhibitors as Anticancer Drugs Z Gagic, D Ruzic, N Djokovic, T Djikic, K Nikolic Frontiers in chemistry 7, 873, 2020 | 92 | 2020 |
One for all? Hitting multiple Alzheimer's disease targets with one drug RE Hughes, K Nikolic, RR Ramsay Frontiers in Neuroscience 10, 177, 2016 | 92 | 2016 |
Drug design for CNS diseases: polypharmacological profiling of compounds using cheminformatic, 3D-QSAR and virtual screening methodologies K Nikolic, L Mavridis, T Djikic, J Vucicevic, D Agbaba, K Yelekci, ... Frontiers in neuroscience 10, 265, 2016 | 83 | 2016 |
Polypharmacology of dopamine receptor ligands S Butini, K Nikolic, S Kassel, H Brückmann, S Filipic, D Agbaba, S Gemma, ... Progress in neurobiology 142, 68-103, 2016 | 77 | 2016 |
Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR … OM Bautista-Aguilera, G Esteban, M Chioua, K Nikolic, D Agbaba, ... Drug Design, Development and Therapy, 1893-1910, 2014 | 77 | 2014 |
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase … OM Bautista-Aguilera, A Samadi, M Chioua, K Nikolic, S Filipic, D Agbaba, ... Journal of medicinal chemistry 57 (24), 10455-10463, 2014 | 71 | 2014 |
Theoretical study of phenolic antioxidants properties in reaction with oxygen-centered radicals KM Nikolic Journal of molecular structure: THEOCHEM 774 (1-3), 95-105, 2006 | 69 | 2006 |
Imidazoline Antihypertensive Drugs: Selective I1‐Imidazoline Receptors Activation K Nikolic, D Agbaba Cardiovascular Therapeutics 30 (4), 209-216, 2012 | 62 | 2012 |
Multiple Targeting Approaches on Histamine H3 Receptor Antagonists MA Khanfar, A Affini, K Lutsenko, K Nikolic, S Butini, H Stark Frontiers in neuroscience 10, 201, 2016 | 53 | 2016 |
Modulating protein–protein interactions with visible‐light‐responsive peptide backbone photoswitches L Albert, A Peñalver, N Djokovic, L Werel, M Hoffarth, D Ruzic, J Xu, ... ChemBioChem 20 (11), 1417-1429, 2019 | 42 | 2019 |
17β-carboxamide steroids–in vitro prediction of human skin permeability and retention using PAMPA technique V Dobričić, B Marković, K Nikolic, V Savić, S Vladimirov, O Čudina European Journal of Pharmaceutical Sciences 52, 95-108, 2014 | 42 | 2014 |
QSAR study of imidazoline antihypertensive drugs K Nikolic, S Filipic, D Agbaba Bioorganic & medicinal chemistry 16 (15), 7134-7140, 2008 | 42 | 2008 |
Prediction of blood–brain barrier permeation of α-adrenergic and imidazoline receptor ligands using PAMPA technique and quantitative-structure permeability relationship analysis J Vucicevic, K Nikolic, V Dobričić, D Agbaba European Journal of Pharmaceutical Sciences 68, 94-105, 2015 | 38 | 2015 |
Procognitive Properties of Drugs with Single and Multitargeting H3 Receptor Antagonist Activities K Nikolic, S Filipic, D Agbaba, H Stark CNS neuroscience & therapeutics 20 (7), 613-623, 2014 | 38 | 2014 |
Partial least square and hierarchical clustering in ADMET modeling: prediction of blood–brain barrier permeation of α-adrenergic and imidazoline receptor ligands K Nikolic, S Filipic, A Smoliński, R Kaliszan, D Agbaba Journal of Pharmacy & Pharmaceutical Sciences 16 (4), 622-647, 2013 | 37 | 2013 |
Phenylpropiophenone derivatives as potential anticancer agents: Synthesis, biological evaluation and quantitative structure–activity relationship study BM Ivković, K Nikolic, BB Ilić, ŽS Žižak, RB Novaković, OA Čudina, ... European Journal of Medicinal Chemistry 63, 239-255, 2013 | 36 | 2013 |
Prediction of hepatic microsomal intrinsic clearance and human clearance values for drugs K Nikolic, D Agababa Journal of Molecular Graphics and Modelling 28 (3), 245-252, 2009 | 36 | 2009 |