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Souvik Sinha
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HKT1; 5 transporter gene expression and association of amino acid substitutions with salt tolerance across rice genotypes
MUS Shohan, S Sinha, FH Nabila, SG Dastidar, ZI Seraj
Frontiers in plant science 10, 1420, 2019
442019
Cholesterol modulates membrane properties and the interaction of gp41 fusion peptide to promote membrane fusion
G Meher, S Sinha, GP Pattnaik, S Ghosh Dastidar, H Chakraborty
The Journal of Physical Chemistry B 123 (33), 7113-7122, 2019
252019
BIM binding remotely regulates BAX activation: insights from the free energy landscapes
S Sinha, A Maity, S Ghosh Dastidar
Journal of Chemical Information and Modeling 58 (2), 370-382, 2018
62018
C-terminal tail insertion of Bcl-x L in membrane occurs via partial unfolding and refolding cycle associating microsolvation
A Maity, S Sinha, D Ganguly, SG Dastidar
Physical Chemistry Chemical Physics 18 (34), 24095-24105, 2016
42016
Machines on genes through the computational microscope
S Sinha, C Pindi, M Ahsan, PR Arantes, G Palermo
Journal of chemical theory and computation 19 (7), 1945-1964, 2023
32023
Twisting and swiveling domain motions in Cas9 to recognize target DNA duplexes, make double-strand breaks, and release cleaved duplexes
J Wang, PR Arantes, M Ahsan, S Sinha, GW Kyro, F Maschietto, B Allen, ...
Frontiers in Molecular Biosciences 9, 1072733, 2023
32023
Dissecting the thermodynamic contributions of the charged residues in the membrane anchoring of Bcl-xl C-terminal domain
A Maity, S Sinha, SG Dastidar
Chemistry and physics of lipids 218, 112-124, 2019
22019
New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity
AM Molina Vargas, S Sinha, R Osborn, PR Arantes, A Patel, S Dewhurst, ...
Nucleic Acids Research, gkad1132, 2023
12023
Unveiling the RNA-mediated allosteric activation discloses functional hotspots in CRISPR-Cas13a
S Sinha, AM Molina Vargas, PR Arantes, A Patel, MR O’Connell, ...
Nucleic Acids Research, gkad1127, 2023
12023
New design strategies for ultra-specific CRISPR-Cas13a-based RNA-diagnostic tools with single-nucleotide mismatch sensitivity
AM Molina Vargas, RM Osborn, S Sinha, PR Arantes, A Patel, S Dewhurst, ...
bioRxiv, 2023.07. 26.550755, 2023
12023
Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage
HB Belato, C Norbrun, J Luo, C Pindi, S Sinha, AM D’Ordine, G Jogl, ...
The Journal of Chemical Physics 157 (22), 2022
12022
Establishing the fundamental rules for genetic code expansion
S Sinha, M Ahsan, G Palermo
Nature chemistry 15 (7), 892-893, 2023
2023
Defining the allosteric role of RNA in the CRISPR-associated Cas13a protein activation
S Sinha, AMM Vergas, PR Arantes, AC Patel, M O’Connell, G Palermo
Biophysical Journal 122 (3), 48a, 2023
2023
Dynamics and thermostability of HNH nuclease in divergent Cas9 species
C Pindi, S Sinha, H Belato, C Norbrun, J Luo, MD Alexandra, G Jogl, ...
Biophysical Journal 122 (3), 138a, 2023
2023
Unveiling Cas8 dynamics and regulation of a transposon-encoded cascade-TniQ complex
AC Patel, S Sinha, PR Arantes, G Palermo
Biophysical Journal 122 (3), 216a, 2023
2023
High-Fidelity, Hyper-Accurate, and Evolved Mutants Rewire Atomic Level Communication in CRISPR-Cas9
E Skeens, S Sinha, M Ahsan, AM D'Ordine, G Jogl, G Palermo, GP Lisi
bioRxiv, 2023.08. 25.554853, 2023
2023
RNA-mediated Allosteric Activation in CRISPR-Cas13a
S Sinha, AM Molina Vargas, PR Arantes, AC Patel, MR O'Connell, ...
bioRxiv, 2023.07. 27.550797, 2023
2023
Atomistic understanding of the RNA-mediated allosteric crosstalk in Cas13a
S Sinha, PR Arantes, A Saha, G Palermo
Biophysical Journal 121 (3), 286a, 2022
2022
N-terminal helices and A domain of archaeal FtsY facilitate SRP54 binding and the association with cell membrane
S Gupta, S Sinha, K Bhakta, A Bhowmick, A Ghosh
bioRxiv, 2022.04. 13.488184, 2022
2022
Shifting Polar Residues Across Primary Sequence Frames of Transmembrane Domains Calibrates Membrane Permeation Thermodynamics
S Sinha, S Ghosh Dastidar
Biochemistry 59 (45), 4353-4366, 2020
2020
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