Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ... Nature genetics 47 (8), 864-871, 2015 | 587 | 2015 |
RAS–MAPK pathway-driven tumor progression is associated with loss of CIC and other genomic aberrations in neuroblastoma TF Eleveld, L Schild, J Koster, DA Zwijnenburg, LK Alles, ME Ebus, ... Cancer research 78 (21), 6297-6307, 2018 | 58 | 2018 |
Engineering large-scale chromosomal deletions by CRISPR-Cas9 TF Eleveld, C Bakali, PP Eijk, P Stathi, LE Vriend, PJ Poddighe, B Ylstra Nucleic acids research 49 (21), 12007-12016, 2021 | 32 | 2021 |
The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors DM Timmerman, TF Eleveld, AJM Gillis, CC Friedrichs, S Hillenius, ... International Journal of Molecular Sciences 22 (21), 11774, 2021 | 23 | 2021 |
Chromosome 3p25. 3 gain is associated with cisplatin resistance and is an independent predictor of poor outcome in male malignant germ cell tumors DM Timmerman, TF Eleveld, S Sriram, LCJ Dorssers, AJM Gillis, ... Journal of Clinical Oncology 40 (26), 3077-3087, 2022 | 18 | 2022 |
Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers NA Schubert, CD Lowery, G Bergthold, J Koster, TF Eleveld, A Rodríguez, ... European Journal of Cancer 130, 168-181, 2020 | 12 | 2020 |
Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma KM Keller, TF Eleveld, L Schild, K van den Handel, M van den Boogaard, ... Frontiers in oncology 12, 929123, 2022 | 8 | 2022 |
Cytogenetic resource enables mechanistic resolution of changing trends in human pluripotent stem cell aberrations linked to feeder-free culture D Stavish, CJ Price, G Gelezauskaite, KA Leonhard, SM Taapken, ... BioRxiv, 2023.09. 21.558777, 2023 | 7 | 2023 |
Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q D Stavish, CJ Price, G Gelezauskaite, H Alsehli, KA Leonhard, ... Stem Cell Reports 19 (8), 1217-1232, 2024 | 3 | 2024 |
MEK inhibition causes BIM stabilization and increased sensitivity to BCL-2 family member inhibitors in RAS-MAPK-mutated neuroblastoma TF Eleveld, L Vernooij, L Schild, B Koopmans, LK Alles, ME Ebus, ... Frontiers in oncology 13, 1130034, 2023 | 3 | 2023 |
MEK inhibition causes Bim stabilization and sensitivity to Bcl2 family member inhibitors in RAS-MAPK mutated neuroblastoma TF Eleveld, L Vernooij, L Schild, B Koopmans, LK Alles, ME Ebus, ... bioRxiv, 2020.02. 12.945089, 2020 | 2 | 2020 |
Recurrence of a mediastinal germ-cell tumor as a somatic-type malignancy: a complex case report CCC Hulsker, MEG Kranendonk, TF Eleveld, AJM Gillis, CP van de Ven, ... International journal of molecular sciences 22 (17), 9310, 2021 | 1 | 2021 |
Abstract A31: Activation of the RAS-MAPK pathway in primary neuroblastoma tumors is associated with poor prognosis TF Eleveld, L Schild, ME Ebus, PG Sluis, EM Westerhout, HN Caron, ... Cancer Research 76 (5_Supplement), A31-A31, 2016 | 1 | 2016 |
Safety Issues Related to Pluripotent Stem Cell-Based Therapies: Tumour Risk S Hillenius, J Montilla-Rojo, TF Eleveld, DCF Salvatori, LHJ Looijenga Pluripotent Stem Cell Therapy for Diabetes, 419-457, 2024 | | 2024 |
Translation research on testicular germ cell tumors TF Eleveld, LHJ Looijenga Tijdschrift voor Urologie 13 (6), 130-135, 2023 | | 2023 |
Engineering large chromosomal deletions by CRISPR-Cas9 TF Eleveld, C Bakali, PP Eijk, P Stathi, PJ Poddighe, B Ylstra bioRxiv, 2020.12. 29.424675, 2020 | | 2020 |
The RAS-MAPK pathway in neuroblastoma TF Eleveld | | 2019 |
Mutations in CIC, DMD and PHOX2B Activate the RAS-MAPK Pathway in Neuroblastoma and Activation of this Pathway Causes Tumor Progression TF Eleveld, L Schild, J Koster, DA Zwijnenburg, L Alles, ME Ebus, ... PEDIATRIC BLOOD & CANCER 64, S6-S6, 2017 | | 2017 |
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations DA Oldridge, TF Eleveld, V Bernard, J Koster, LC Daage, SJ Diskin, ... Cancer Research 75 (15_Supplement), 2980-2980, 2015 | | 2015 |
Abstract B41: Whole genome sequencing identifies tumor evolution events in relapse neuroblastoma TF Eleveld, L Schild, J Koster, D Zwijnenburg, ME Ebus, PS Van, ... Cancer Research 74 (20_Supplement), B41-B41, 2014 | | 2014 |