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Alexandra K. Davies
Alexandra K. Davies
Lecturer in Cell Biology, University of Manchester
在 manchester.ac.uk 的电子邮件经过验证 - 首页
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AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A
AK Davies, DN Itzhak, JR Edgar, TL Archuleta, J Hirst, LP Jackson, ...
Nature communications 9 (1), 3958, 2018
1302018
Adaptor protein complexes and disease at a glance
A Sanger, J Hirst, AK Davies, MS Robinson
Journal of Cell Science 132 (20), jcs222992, 2019
1012019
Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking
R Behne, J Teinert, M Wimmer, A D’Amore, AK Davies, JM Scarrott, ...
Human molecular genetics 29 (2), 320-334, 2020
622020
AP-4-associated hereditary spastic paraplegia
D Ebrahimi-Fakhari, R Behne, AK Davies, J Hirst
462018
Molecular basis for the interaction between AP4 β4 and its accessory protein, tepsin
MN Frazier, AK Davies, M Voehler, AK Kendall, GHH Borner, WJ Chazin, ...
Traffic 17 (4), 400-415, 2016
292016
AP-4-mediated axonal transport controls endocannabinoid production in neurons
AK Davies, JE Alecu, M Ziegler, CG Vasilopoulou, F Merciai, H Jumo, ...
Nature Communications 13 (1), 1058, 2022
252022
Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells
P Rodríguez-Silvestre, M Laub, PA Krawczyk, AK Davies, JP Schessner, ...
Science 380 (6651), 1258-1265, 2023
232023
Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development
MS Nahorski, GHH Borner, SS Shaikh, AK Davies, L Al-Gazali, ...
Scientific reports 8 (1), 2340, 2018
182018
High-throughput imaging of ATG9A distribution as a diagnostic functional assay for adaptor protein complex 4-associated hereditary spastic paraplegia
D Ebrahimi-Fakhari, JE Alecu, B Brechmann, M Ziegler, K Eberhardt, ...
Brain communications 3 (4), fcab221, 2021
142021
Deep and fast label-free Dynamic Organellar Mapping
JP Schessner, V Albrecht, AK Davies, P Sinitcyn, GHH Borner
Nature Communications 14 (1), 5252, 2023
82023
AP-4 mediates vesicular transport of the 2-AG endocannabinoid producing enzyme DAGLB
AK Davies, M Ziegler, H Jumo, WA Saber, D Ebrahimi-Fakhari, ...
BiorXiv, 2020.10. 25.353995, 2020
32020
The role of the AP-1 adaptor complex in outgoing and incoming membrane traffic
MS Robinson, R Antrobus, A Sanger, AK Davies, DC Gershlick
The Journal of cell biology 223 (7), 2024
22024
High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia
A Saffari, B Brechmann, C Böger, WA Saber, H Jumo, D Whye, D Wood, ...
Nature Communications 15 (1), 584, 2024
22024
From the Cover: Does the Assessment of Nondisjunction Provide a More Sensitive Assay for the Detection of Aneugens?
JM Elloway, AK Davies, JE Hayes, AT Doherty
Toxicological Sciences 157 (1), 20-29, 2017
22017
High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia
A Saffari, B Brechmann, C Boeger, WA Saber, D Whye, D Wood, ...
12023
AP-4-mediated axonal transport controls endocannabinoid production in neurons-Image analysis pipelines
AK Davies, JE Alecu, M Ziegler, CG Vasilopoulou, F Merciai, H Jumo, ...
Zenodo, 2021
12021
AP-4 vesicles unmasked by organellar proteomics to reveal their cargo and machinery
AK Davies, DN Itzhak, JR Edgar, TL Archuleta, J Hirst, LP Jackson, ...
bioRxiv, 235226, 2017
12017
An investigation into non-disjunction with aneugenic chemicals
AK Davies, AT Doherty, A Wilson, MR O'Donovan
Mutagenesis 27 (6), 804-804, 2012
12012
Data independent acquisition enables deep and fast label-free dynamic organellar mapping
JP Schessner, V Albrecht, AK Davies, P Sinitcyn, GHH Borner
bioRxiv, 2021.11. 09.467934, 2021
2021
High-Throughput Imaging of ATG9A Distribution as a Diagnostic Functional Assay for Adaptor Protein Complex 4-Associated Hereditary Spastic Paraplegia
J Alecu, B Brechmann, M Ziegler, K Eberhardt, H Jumo, A D'Amore, ...
ANNALS OF NEUROLOGY 90, S136-S136, 2021
2021
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