Structural disorder of monomeric α-synuclein persists in mammalian cells FX Theillet, A Binolfi, B Bekei, A Martorana, HM Rose, M Stuiver, S Verzini, ... Nature 530 (7588), 45-50, 2016 | 888 | 2016 |
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs) FX Theillet, A Binolfi, T Frembgen-Kesner, K Hingorani, M Sarkar, C Kyne, ... Chemical reviews 114 (13), 6661-6714, 2014 | 479 | 2014 |
Interaction of α-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement A Binolfi, RM Rasia, CW Bertoncini, M Ceolin, M Zweckstetter, ... Journal of the American Chemical Society 128 (30), 9893-9901, 2006 | 427 | 2006 |
Thermodynamics of protein destabilization in live cells J Danielsson, X Mu, L Lang, H Wang, A Binolfi, FX Theillet, B Bekei, ... Proceedings of the National Academy of Sciences 112 (40), 12402-12407, 2015 | 213 | 2015 |
Site-specific interactions of Cu (II) with α and β-synuclein: Bridging the molecular gap between metal binding and aggregation A Binolfi, GR Lamberto, R Duran, L Quintanar, CW Bertoncini, JM Souza, ... Journal of the American Chemical Society 130 (35), 11801-11812, 2008 | 199 | 2008 |
Bacterial in-cell NMR of human α-synuclein: a disordered monomer by nature? A Binolfi, FX Theillet, P Selenko Biochemical Society Transactions 40 (5), 950-954, 2012 | 184 | 2012 |
Bioinorganic chemistry of Parkinson’s disease: structural determinants for the copper-mediated amyloid formation of alpha-synuclein A Binolfi, EE Rodriguez, D Valensin, N D’Amelio, E Ippoliti, G Obal, ... Inorganic chemistry 49 (22), 10668-10679, 2010 | 163 | 2010 |
Structural characterization of the intrinsically unfolded protein β-synuclein, a natural negative regulator of α-synuclein aggregation CW Bertoncini, RM Rasia, GR Lamberto, A Binolfi, M Zweckstetter, ... Journal of molecular biology 372 (3), 708-722, 2007 | 138 | 2007 |
Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease A Binolfi, L Quintanar, CW Bertoncini, C Griesinger, CO Fernández Coordination Chemistry Reviews 256 (19-20), 2188-2201, 2012 | 137 | 2012 |
Structural and mechanistic basis behind the inhibitory interaction of PcTS on α-synuclein amyloid fibril formation GR Lamberto, A Binolfi, ML Orcellet, CW Bertoncini, M Zweckstetter, ... Proceedings of the National Academy of Sciences 106 (50), 21057-21062, 2009 | 125 | 2009 |
Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species F González-Lizárraga, SB Socías, CL Ávila, CM Torres-Bugeau, ... Scientific reports 7 (1), 1-13, 2017 | 120 | 2017 |
Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites A Binolfi, A Limatola, S Verzini, J Kosten, FX Theillet, H May Rose, ... Nature communications 7 (1), 10251, 2016 | 112 | 2016 |
Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts FX Theillet, HM Rose, S Liokatis, A Binolfi, R Thongwichian, M Stuiver, ... Nature protocols 8 (7), 1416-1432, 2013 | 96 | 2013 |
Exploring the structural details of Cu (I) binding to α-synuclein by NMR spectroscopy A Binolfi, AA Valiente-Gabioud, R Duran, M Zweckstetter, C Griesinger, ... Journal of the American Chemical Society 133 (2), 194-196, 2011 | 95 | 2011 |
Site-specific copper-catalyzed oxidation of α-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson’s disease MC Miotto, EE Rodriguez, AA Valiente-Gabioud, V Torres-Monserrat, ... Inorganic chemistry 53 (9), 4350-4358, 2014 | 94 | 2014 |
Oral yeast carriage in HIV‐infected and non‐infected populations in Rosario, Argentina AG Luque, MS Biasoli, ME Tosello, A Binolfi, S Lupo, HM Magaró Mycoses 52 (1), 53-59, 2009 | 80 | 2009 |
Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding MC Miotto, AA Valiente-Gabioud, G Rossetti, M Zweckstetter, P Carloni, ... Journal of the American Chemical Society 137 (20), 6444-6447, 2015 | 79 | 2015 |
Efficient modification of alpha-synuclein serine 129 by protein kinase CK1 requires phosphorylation of tyrosine 125 as a priming event J Kosten, A Binolfi, M Stuiver, S Verzini, FX Theillet, B Bekei, ... ACS chemical neuroscience 5 (12), 1203-1208, 2014 | 73 | 2014 |
Real-time NMR monitoring of biological activities in complex physiological environments MJ Smith, CB Marshall, FX Theillet, A Binolfi, P Selenko, M Ikura Current opinion in structural biology 32, 39-47, 2015 | 72 | 2015 |
Structural basis behind the interaction of Zn2+ with the protein α-synuclein and the Aβ peptide: A comparative analysis AA Valiente-Gabioud, V Torres-Monserrat, L Molina-Rubino, A Binolfi, ... Journal of inorganic biochemistry 117, 334-341, 2012 | 62 | 2012 |