Single cell profiling of potentiated phospho-protein networks in cancer cells JM Irish, R Hovland, PO Krutzik, OD Perez, Ø Bruserud, BT Gjertsen, ... Cell 118 (2), 217-228, 2004 | 862 | 2004 |
Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line JS Armstrong, KK Steinauer, B Hornung, JM Irish, P Lecane, GW Birrell, ... Cell Death & Differentiation 9 (3), 252-263, 2002 | 592 | 2002 |
Web‐based analysis and publication of flow cytometry experiments N Kotecha, PO Krutzik, JM Irish Current protocols in cytometry 53 (1), 10.17. 1-10.17. 24, 2010 | 553 | 2010 |
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy DB Johnson, MV Estrada, R Salgado, V Sanchez, DB Doxie, SR Opalenik, ... Nature communications 7 (1), 10582, 2016 | 529 | 2016 |
Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications PO Krutzik, JM Irish, GP Nolan, OD Perez Clinical immunology 110 (3), 206-221, 2004 | 429 | 2004 |
Mapping normal and cancer cell signalling networks: towards single-cell proteomics JM Irish, N Kotecha, GP Nolan Nature Reviews Cancer 6 (2), 146-155, 2006 | 389 | 2006 |
Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation MR Green, S Kihira, CL Liu, RV Nair, R Salari, AJ Gentles, J Irish, H Stehr, ... Proceedings of the National Academy of Sciences 112 (10), E1116-E1125, 2015 | 367 | 2015 |
Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma MR Green, AJ Gentles, RV Nair, JM Irish, S Kihira, CL Liu, I Kela, ... Blood, The Journal of the American Society of Hematology 121 (9), 1604-1611, 2013 | 364 | 2013 |
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma PJ Siska, KE Beckermann, FM Mason, G Andrejeva, AR Greenplate, ... JCI insight 2 (12), 2017 | 306 | 2017 |
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates N Kotecha, NJ Flores, JM Irish, EF Simonds, DS Sakai, S Archambeault, ... Cancer cell 14 (4), 335-343, 2008 | 283 | 2008 |
Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells JM Irish, DK Czerwinski, GP Nolan, R Levy Blood 108 (9), 3135-3142, 2006 | 214 | 2006 |
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression JM Irish, JH Myklebust, AA Alizadeh, R Houot, JP Sharman, ... Proceedings of the National Academy of Sciences 107 (29), 12747-12754, 2010 | 190 | 2010 |
High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells JH Myklebust, JM Irish, J Brody, DK Czerwinski, R Houot, HE Kohrt, ... Blood, The Journal of the American Society of Hematology 121 (8), 1367-1376, 2013 | 187 | 2013 |
Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion R Houot, MJ Goldstein, HE Kohrt, JH Myklebust, AA Alizadeh, JT Lin, ... Blood, The Journal of the American Society of Hematology 114 (16), 3431-3438, 2009 | 165 | 2009 |
Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data KE Diggins, PB Ferrell Jr, JM Irish Methods 82, 55-63, 2015 | 145 | 2015 |
Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry JM Irish, DK Czerwinski, GP Nolan, R Levy The Journal of Immunology 177 (3), 1581-1589, 2006 | 143 | 2006 |
Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment S Kordasti, B Costantini, T Seidl, P Perez Abellan, M Martinez Llordella, ... Blood, The Journal of the American Society of Hematology 128 (9), 1193-1205, 2016 | 139 | 2016 |
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells MEM Van Meter, E Díaz-Flores, JA Archard, E Passegué, JM Irish, ... Blood 109 (9), 3945-3952, 2007 | 136 | 2007 |
Single cell analysis of human tissues and solid tumors with mass cytometry N Leelatian, DB Doxie, AR Greenplate, BC Mobley, JM Lehman, ... Cytometry Part B: Clinical Cytometry 92 (1), 68-78, 2017 | 112 | 2017 |
Characterizing cell subsets using marker enrichment modeling KE Diggins, AR Greenplate, N Leelatian, CE Wogsland, JM Irish Nature methods 14 (3), 275-278, 2017 | 108 | 2017 |