The mutagenesis protein UmuC is a DNA polymerase activated by UmuD′, RecA, and SSB and is specialized for translesion replication NB Reuven, G Arad, A Maor-Shoshani, Z Livneh Journal of Biological Chemistry 274 (45), 31763-31766, 1999 | 437 | 1999 |
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage D Levy, Y Adamovich, N Reuven, Y Shaul Molecular cell 29 (3), 350-361, 2008 | 386 | 2008 |
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. N Bacher, Y Zisman, E Berent, E Livneh Mol Cell Biol 11 (1), 126-33, 1991 | 301 | 1991 |
20S proteasomes and protein degradation “by default” G Asher, N Reuven, Y Shaul Bioessays 28 (8), 844-849, 2006 | 254 | 2006 |
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73 D Levy, Y Adamovich, N Reuven, Y Shaul Cell Death & Differentiation 14 (4), 743-751, 2007 | 249 | 2007 |
Enzymatic basis for hydrolytic versus phosphorolytic mRNA degradation in Escherichia coli and Bacillus subtilis. MP Deutscher, NB Reuven Proceedings of the National Academy of Sciences 88 (8), 3277-3280, 1991 | 208 | 1991 |
Ubiquitin-independent p53 proteasomal degradation P Tsvetkov, N Reuven, Y Shaul Cell Death & Differentiation 17 (1), 103-108, 2010 | 165 | 2010 |
The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitro NB Reuven, AE Staire, RS Myers, SK Weller Journal of virology 77 (13), 7425-7433, 2003 | 164 | 2003 |
The mutagenesis proteins UmuD′ and UmuC prevent lethal frameshifts while increasing base substitution mutations NB Reuven, G Tomer, Z Livneh Molecular cell 2 (2), 191-199, 1998 | 153 | 1998 |
Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis A Maor-Shoshani, NB Reuven, G Tomer, Z Livneh Proceedings of the National Academy of Sciences 97 (2), 565-570, 2000 | 138 | 2000 |
Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome P Tsvetkov, G Asher, A Paz, N Reuven, JL Sussman, I Silman, Y Shaul Proteins: Structure, Function, and Bioinformatics 70 (4), 1357-1366, 2008 | 135 | 2008 |
The nanny model for IDPs P Tsvetkov, N Reuven, Y Shaul Nature chemical biology 5 (11), 778-781, 2009 | 133 | 2009 |
The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1 Y Adamovich, A Shlomai, P Tsvetkov, KB Umansky, N Reuven, JL Estall, ... Molecular and cellular biology 33 (13), 2603-2613, 2013 | 116 | 2013 |
Multiple exoribonucleases are required for the 3′ processing of Escherichia coli tRNA precursors in vivo NB Reuven, MP Deutscher The FASEB journal 7 (1), 143-148, 1993 | 83 | 1993 |
Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease NB Reuven, S Willcox, JD Griffith, SK Weller Journal of molecular biology 342 (1), 57-71, 2004 | 82 | 2004 |
Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response S Smith, N Reuven, KN Mohni, AJ Schumacher, SK Weller Journal of virology 88 (17), 10146-10156, 2014 | 80 | 2014 |
The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl N Reuven, J Adler, V Meltser, Y Shaul Cell Death & Differentiation 20 (10), 1330-1340, 2013 | 75 | 2013 |
Oncogenic addiction to high 26S proteasome level P Tsvetkov, J Adler, N Myers, A Biran, N Reuven, Y Shaul Cell death & disease 9 (7), 773, 2018 | 70 | 2018 |
Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response*♦ P Tsvetkov, N Reuven, C Prives, Y Shaul Journal of biological chemistry 284 (39), 26234-26242, 2009 | 68 | 2009 |
The UL12. 5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus NB Reuven, S Antoku, SK Weller Journal of virology 78 (9), 4599-4608, 2004 | 68 | 2004 |