Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1405 | 2013 |
Hepatic acute phase proteins–regulation by IL-6-and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling JG Bode, U Albrecht, D Häussinger, PC Heinrich, F Schaper European journal of cell biology 91 (6-7), 496-505, 2012 | 457 | 2012 |
The macrophage response towards LPS and its control through the p38MAPK–STAT3 axis JG Bode, C Ehlting, D Häussinger Cellular signalling 24 (6), 1185-1194, 2012 | 445 | 2012 |
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses C Ehrhardt, T Wolff, S Pleschka, O Planz, W Beermann, JG Bode, ... Journal of virology 81 (7), 3058-3067, 2007 | 426 | 2007 |
IFN‐α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling‐3 JG Bode, S Ludwig, C Ehrhardt, A Erhardt, U Albrecht, F Schaper, ... The FASEB Journal 17 (3), 1-16, 2003 | 416 | 2003 |
Influenza A virus inhibits type I IFN signaling via NF-κB-dependent induction of SOCS-3 expression EK Pauli, M Schmolke, T Wolff, D Viemann, J Roth, JG Bode, S Ludwig PLoS pathogens 4 (11), e1000196, 2008 | 333 | 2008 |
LPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages JG Bode, A Nimmesgern, J Schmitz, F Schaper, M Schmitt, W Frisch, ... FEBS letters 463 (3), 365-370, 1999 | 268 | 1999 |
Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-α involves activation of the MKK6/p38MAPK/MK2 cascade C Ehlting, WS Lai, F Schaper, ED Brenndörfer, RJ Matthes, PC Heinrich, ... The Journal of Immunology 178 (5), 2813-2826, 2007 | 153 | 2007 |
Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages K Haselow, JG Bode, M Wammers, C Ehlting, V Keitel, L Kleinebrecht, ... Journal of leukocyte biology 94 (6), 1253-1264, 2013 | 144 | 2013 |
Expression of the peripheral-type benzodiazepine receptor and apoptosis induction in hepatic stellate cells R Fischer, M Schmitt, JG Bode, D Häussinger Gastroenterology 120 (5), 1212-1226, 2001 | 141 | 2001 |
BMP-9 interferes with liver regeneration and promotes liver fibrosis K Breitkopf-Heinlein, C Meyer, C König, H Gaitantzi, A Addante, ... Gut 66 (5), 939-954, 2017 | 132 | 2017 |
The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription … JG Bode, P Gatsios, S Ludwig, UR Rapp, D Häussinger, PC Heinrich, ... Journal of Biological Chemistry 274 (42), 30222-30227, 1999 | 120 | 1999 |
Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation S Radtke, S Wüller, X Yang, BE Lippok, B Mütze, C Mais, HSV de Leur, ... Journal of cell science 123 (6), 947-959, 2010 | 119 | 2010 |
Infusion of CD133+ bone marrow–derived stem cells after selective portal vein embolization enhances functional hepatic reserves after extended right hepatectomy: a … JS am Esch, M Schmelzle, G Fürst, SC Robson, A Krieg, C Duhme, ... Annals of surgery 255 (1), 79-85, 2012 | 114 | 2012 |
The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130 L Terstegen, P Gatsios, JG Bode, F Schaper, PC Heinrich, L Graeve Journal of Biological Chemistry 275 (25), 18810-18817, 2000 | 100 | 2000 |
The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcription JG Bode, S Ludwig, CAC Freitas, F Schaper, M Ruhl, S Melmed, ... Walter de Gruyter 382 (10), 1447-1453, 2001 | 97 | 2001 |
Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor–induced signal transduction by cleavage of the T‐cell protein tyrosine phosphatase ED Brenndörfer, J Karthe, L Frelin, P Cebula, A Erhardt, ... Hepatology 49 (6), 1810-1820, 2009 | 95 | 2009 |
Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase N Qvartskhava, PA Lang, B Görg, VI Pozdeev, MP Ortiz, KS Lang, ... Proceedings of the National Academy of Sciences 112 (17), 5521-5526, 2015 | 94 | 2015 |
The inhibitory effect of IL-1β on IL-6-induced α2-macroglobulin expression is due to activation of NF-κB JG Bode, R Fischer, D Häussinger, L Graeve, PC Heinrich, F Schaper The Journal of Immunology 167 (3), 1469-1481, 2001 | 94 | 2001 |
Role of TGR5 (GPBAR1) in liver disease V Keitel, D Häussinger Seminars in liver disease 38 (04), 333-339, 2018 | 88 | 2018 |