Molecular architecture and assembly of the eukaryotic proteasome RJ Tomko Jr, M Hochstrasser Annual review of biochemistry 82, 415-445, 2013 | 445 | 2013 |
microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells P Wang, F Zou, X Zhang, H Li, A Dulak, RJ Tomko Jr, JS Lazo, Z Wang, ... Cancer research 69 (20), 8157-8165, 2009 | 359 | 2009 |
Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly RJ Tomko, M Funakoshi, K Schneider, J Wang, M Hochstrasser Molecular cell 38 (3), 393-403, 2010 | 192 | 2010 |
Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base M Funakoshi, RJ Tomko, H Kobayashi, M Hochstrasser Cell 137 (5), 887-899, 2009 | 191 | 2009 |
Expanded coverage of the 26S proteasome conformational landscape reveals mechanisms of peptidase gating MR Eisele, RG Reed, T Rudack, A Schweitzer, F Beck, I Nagy, G Pfeifer, ... Cell reports 24 (5), 1301-1315. e5, 2018 | 121 | 2018 |
Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining RJ Tomko, M Hochstrasser Molecular cell 44 (6), 907-917, 2011 | 86 | 2011 |
A single α helix drives extensive remodeling of the proteasome lid and completion of regulatory particle assembly RJ Tomko, DW Taylor, ZA Chen, HW Wang, J Rappsilber, M Hochstrasser Cell 163 (2), 432-444, 2015 | 73 | 2015 |
The intrinsically disordered Sem1 protein functions as a molecular tether during proteasome lid biogenesis RJ Tomko, M Hochstrasser Molecular cell 53 (3), 433-443, 2014 | 72 | 2014 |
Autophagic clearance of proteasomes in yeast requires the conserved sorting nexin Snx4 AA Nemec, LA Howell, AK Peterson, MA Murray, RJ Tomko Journal of Biological Chemistry 292 (52), 21466-21480, 2017 | 71 | 2017 |
Order of the proteasomal ATPases and eukaryotic proteasome assembly RJ Tomko, M Hochstrasser Cell biochemistry and biophysics 60, 13-20, 2011 | 67 | 2011 |
Independent mechanistic inhibition of cdc25 phosphatases by a natural product caulibugulone M Brisson, C Foster, P Wipf, B Joo, RJ Tomko, T Nguyen, JS Lazo Molecular pharmacology 71 (1), 184-192, 2007 | 56 | 2007 |
Airing out an antioxidant role for the tumor suppressor p53 RJ Tomko, P Bansal, JS Lazo Molecular interventions 6 (1), 23, 2006 | 41 | 2006 |
Proteasomes: isolation and activity assays Y Li, RJ Tomko Jr, M Hochstrasser Current protocols in cell biology 67 (1), 3.43. 1-3.43. 20, 2015 | 40 | 2015 |
3′–5′ tRNAHis guanylyltransferase in bacteria IU Heinemann, L Randau, RJ Tomko Jr, D Söll FEBS letters 584 (16), 3567-3572, 2010 | 40 | 2010 |
Wake-sleep cycles are severely disrupted by diseases affecting cytoplasmic homeostasis S Beesley, DW Kim, M D’Alessandro, Y Jin, K Lee, H Joo, Y Young, ... Proceedings of the National Academy of Sciences 117 (45), 28402-28411, 2020 | 33 | 2020 |
Disruptions to the limb muscle core molecular clock coincide with changes in mitochondrial quality control following androgen depletion ML Rossetti, KA Esser, C Lee, RJ Tomko Jr, AM Eroshkin, BS Gordon American Journal of Physiology-Endocrinology and Metabolism 317 (4), E631-E645, 2019 | 33 | 2019 |
The anaphase-promoting complex regulates the degradation of the inner nuclear membrane protein Mps3 BA Koch, H Jin, RJ Tomko Jr, HG Yu Journal of Cell Biology 218 (3), 839-854, 2019 | 28 | 2019 |
A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway B Sá-Moura, M Funakoshi, RJ Tomko, RJ Dohmen, Z Wu, J Peng, ... Journal of Biological Chemistry 288 (47), 33682-33696, 2013 | 28 | 2013 |
Multimodal control of Cdc25A by nitrosative stress RJ Tomko Jr, JS Lazo Cancer research 68 (18), 7457-7465, 2008 | 27 | 2008 |
The Cdc48 complex alleviates the cytotoxicity of misfolded proteins by regulating ubiquitin homeostasis R Higgins, MH Kabbaj, D Sherwin, LA Howell, A Hatcher, RJ Tomko, ... Cell reports 32 (2), 2020 | 24 | 2020 |